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lestaurtinib [cytosol]
Stable Identifier
R-ALL-9695703
Type
ChemicalDrug
Compartment
cytosol
Synonyms
CEP-701, KT-5555, SP924
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Canis familiaris
Mus musculus
Sus scrofa
Expand all
Immune System (Bos taurus)
Cytokine Signaling in Immune system (Bos taurus)
FLT3 Signaling (Bos taurus)
FLT3LG dimer:FLT3 dimer autophosphorylates (Bos taurus)
FLT3LG dimer:FLT3:FLT3-binding type I TKIs [plasma membrane] (Bos taurus)
type I FLT3-binding TKIs [cytosol]
lestaurtinib [cytosol]
Immune System (Canis familiaris)
Cytokine Signaling in Immune system (Canis familiaris)
FLT3 Signaling (Canis familiaris)
FLT3LG dimer:FLT3 dimer autophosphorylates (Canis familiaris)
FLT3LG dimer:FLT3:FLT3-binding type I TKIs [plasma membrane] (Canis familiaris)
type I FLT3-binding TKIs [cytosol]
lestaurtinib [cytosol]
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
FLT3 signaling in disease (Homo sapiens)
Drug resistance of FLT3 mutants (Homo sapiens)
lestaurtinib-resistant FLT3 mutants (Homo sapiens)
lestaurtinib-resistant FLT3 mutants don't bind lestaurtinib (Homo sapiens)
lestaurtinib [cytosol]
FLT3 mutants bind TKIs (Homo sapiens)
FLT mutants bind type I TKIs (Homo sapiens)
type I FLT3-binding TKIs [cytosol]
lestaurtinib [cytosol]
type I TKI-sensitive FLT3 mutants:type I TKIs [plasma membrane] (Homo sapiens)
type I FLT3-binding TKIs [cytosol]
lestaurtinib [cytosol]
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
FLT3 Signaling (Homo sapiens)
FLT3 binds type I TKI (Homo sapiens)
type I FLT3-binding TKIs [cytosol]
lestaurtinib [cytosol]
FLT3LG dimer:FLT3:FLT3-binding type I TKIs [plasma membrane] (Homo sapiens)
type I FLT3-binding TKIs [cytosol]
lestaurtinib [cytosol]
FLT3LG dimer:FLT3 dimer autophosphorylates (Homo sapiens)
type I FLT3-binding TKIs [cytosol]
lestaurtinib [cytosol]
FLT3LG dimer:FLT3:FLT3-binding type I TKIs [plasma membrane] (Homo sapiens)
type I FLT3-binding TKIs [cytosol]
lestaurtinib [cytosol]
Immune System (Mus musculus)
Cytokine Signaling in Immune system (Mus musculus)
FLT3 Signaling (Mus musculus)
FLT3LG dimer:FLT3 dimer autophosphorylates (Mus musculus)
FLT3LG dimer:FLT3:FLT3-binding type I TKIs [plasma membrane] (Mus musculus)
type I FLT3-binding TKIs [cytosol]
lestaurtinib [cytosol]
Immune System (Sus scrofa)
Cytokine Signaling in Immune system (Sus scrofa)
FLT3 Signaling (Sus scrofa)
FLT3LG dimer:FLT3 dimer autophosphorylates (Sus scrofa)
FLT3LG dimer:FLT3:FLT3-binding type I TKIs [plasma membrane] (Sus scrofa)
type I FLT3-binding TKIs [cytosol]
lestaurtinib [cytosol]
External Reference Information
External Reference
lestaurtinib [Guide to Pharmacology:5672]
Participates
as an input of
lestaurtinib-resistant FLT3 mutants don't bind lestaurtinib (Homo sapiens)
as a member of
type I FLT3-binding TKIs [cytosol]
Disease
Name
Identifier
Synonyms
cancer
DOID:162
malignant tumor, malignant neoplasm, primary cancer
Cross References
PharmacoDB
PDBC00024
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![lestaurtinib [cytosol] icon](/icon/R-ICO-014440.svg){kind=icon}
