mRNA Transcript Targeted by HuR Phosphorylated on Ser158 and Ser318. [nucleoplasm]

Stable Identifier
R-ALL-450605
Type
OtherEntity
Compartment
nucleoplasm
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General

Phosphorylated HuR (phosphoserine158 and phosphoserine318) binds AU-rich elements in the Cyclooxygenase-2 (COX-2, PTGS2) mRNA.

Literature References
PubMed ID Title Journal Year
17392515 Protein kinase C alpha-dependent phosphorylation of the mRNA-stabilizing factor HuR: implications for posttranscriptional regulation of cyclooxygenase-2

Pfeilschifter, J, Müller, R, Doller, A, Huwiler, A, Eberhardt, W, Radeke, HH

Mol Biol Cell 2007
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ChEBI
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