mRNA Transcript Targeted by AUF1(hnRNP D0) [cytosol]

Stable Identifier
R-ALL-450444
Type
OtherEntity
Compartment
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General

AUF1 (hnRNP D0) binds AU-rich elements in mRNAs encoding Interleukin-1 beta (IL1B), Tumor Necrosis Factor alpha (TNFA), Cyclin-dependent kinase inhibitor 1 (CDNK1A, p21), Cyclin-D1 (CCND1), Granulocyte-macrophage colony stimulating factor (GM-CSF, CSF2), inducible Nitric oxide synthase (iNOS, NOS2), Proto-oncogene cFos (FOS), Myc proto-oncogene (MYC), Apoptosis regulator Bcl-2 (BCL2).

Literature References
PubMed ID Title Journal Year
9346902 Structural determinants in AUF1 required for high affinity binding to A + U-rich elements

DeMaria, CT, Sun, Y, Long, L, Wagner, BJ, Brewer, G

J Biol Chem 1997
19074427 Similar regulation of human inducible nitric-oxide synthase expression by different isoforms of the RNA-binding protein AUF1

Pautz, A, Linker, K, Altenhöfer, S, Heil, S, Schmidt, N, Art, J, Knauer, S, Stauber, R, Sadri, N, Pont, A, Schneider, RJ, Kleinert, H

J Biol Chem 2009
17486099 Competitive binding of AUF1 and TIAR to MYC mRNA controls its translation

Liao, B, Hu, Y, Brewer, G

Nat Struct Mol Biol 2007
11856759 AUF1 Is a bcl-2 A + U-rich element-binding protein involved in bcl-2 mRNA destabilization during apoptosis

Lapucci, A, Donnini, M, Papucci, L, Witort, E, Tempestini, A, Bevilacqua, A, Nicolin, A, Brewer, G, Schiavone, N, Capaccioli, S

J Biol Chem 2002
8246982 Purification, characterization, and cDNA cloning of an AU-rich element RNA-binding protein, AUF1

Zhang, W, Wagner, BJ, Ehrenman, K, Schaefer, AW, DeMaria, CT, Crater, D, DeHaven, K, Long, L, Brewer, G

Mol Cell Biol 1993
15257295 Concurrent versus individual binding of HuR and AUF1 to common labile target mRNAs

Lal, A, Mazan-Mamczarz, K, Kawai, T, Yang, X, Martindale, JL, Gorospe, M

EMBO J 2004
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Cross References
ChEBI