mRNA Transcript Targeted by AUF1(hnRNP D0) [cytosol]

Stable Identifier
R-ALL-450444
Type
OtherEntity
Compartment
cytosol
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General
AUF1 (hnRNP D0) binds AU-rich elements in mRNAs encoding Interleukin-1 beta (IL1B), Tumor Necrosis Factor alpha (TNFA), Cyclin-dependent kinase inhibitor 1 (CDNK1A, p21), Cyclin-D1 (CCND1), Granulocyte-macrophage colony stimulating factor (GM-CSF, CSF2), inducible Nitric oxide synthase (iNOS, NOS2), Proto-oncogene cFos (FOS), Myc proto-oncogene (MYC), Apoptosis regulator Bcl-2 (BCL2).
Literature References
PubMed ID Title Journal Year
19074427 Similar regulation of human inducible nitric-oxide synthase expression by different isoforms of the RNA-binding protein AUF1

Kleinert, H, Schneider, RJ, Art, J, Knauer, S, Pont, A, Stauber, R, Pautz, A, Sadri, N, Heil, S, Altenhöfer, S, Linker, K, Schmidt, N

J Biol Chem 2009
9346902 Structural determinants in AUF1 required for high affinity binding to A + U-rich elements

Brewer, G, Sun, Y, DeMaria, CT, Wagner, BJ, Long, L

J Biol Chem 1997
17486099 Competitive binding of AUF1 and TIAR to MYC mRNA controls its translation

Brewer, G, Hu, Y, Liao, B

Nat Struct Mol Biol 2007
11856759 AUF1 Is a bcl-2 A + U-rich element-binding protein involved in bcl-2 mRNA destabilization during apoptosis

Lapucci, A, Brewer, G, Bevilacqua, A, Witort, E, Capaccioli, S, Papucci, L, Tempestini, A, Nicolin, A, Schiavone, N, Donnini, M

J Biol Chem 2002
8246982 Purification, characterization, and cDNA cloning of an AU-rich element RNA-binding protein, AUF1

Crater, D, Brewer, G, DeHaven, K, Zhang, W, Schaefer, AW, DeMaria, CT, Long, L, Ehrenman, K, Wagner, BJ

Mol Cell Biol 1993
15257295 Concurrent versus individual binding of HuR and AUF1 to common labile target mRNAs

Gorospe, M, Yang, X, Mazan-Mamczarz, K, Lal, A, Kawai, T, Martindale, JL

EMBO J 2004
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