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(GlcNAc)2 (Man)5 (PP-Dol)1 [integral component of cytoplasmic side of endoplasmic reticulum membrane]
Stable Identifier
R-ALL-449332
Type
Chemical Compound [SimpleEntity]
Compartment
integral component of cytoplasmic side of endoplasmic reticulum membrane
Synonyms
glycan G00006, (alpha-D-mannosyl)4-beta-D-mannosyldiacetylchitobiosyldiphosphodolichol
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of metabolism (Homo sapiens)
Diseases of glycosylation (Homo sapiens)
Diseases associated with N-glycosylation of proteins (Homo sapiens)
Defective RFT1 causes CDG-1n (Homo sapiens)
Defective RFT1 does not flip the N-glycan precursor (Homo sapiens)
(GlcNAc)2 (Man)5 (PP-Dol)1 [integral component of cytoplasmic side of endoplasmic reticulum membrane]
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Asparagine N-linked glycosylation (Homo sapiens)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Homo sapiens)
ALG11 transfers the fourth and fifth Man to the N-glycan precursor (Homo sapiens)
(GlcNAc)2 (Man)5 (PP-Dol)1 [integral component of cytoplasmic side of endoplasmic reticulum membrane]
Flipping of the N-glycan precursor to inside the ER (Homo sapiens)
(GlcNAc)2 (Man)5 (PP-Dol)1 [integral component of cytoplasmic side of endoplasmic reticulum membrane]
External Reference Information
External Reference
(alpha-D-mannosyl)4-beta-D-mannosyldiacetylchitobiosyldiphosphodolichol [ChEBI:37633]
Participates
as an input of
Defective RFT1 does not flip the N-glycan precursor (Homo sapiens)
Flipping of the N-glycan precursor into the ER lumen (Saccharomyces cerevisiae)
Flipping of the N-glycan precursor to inside the ER (Homo sapiens)
as an output of
Addition of the fourth and fifth mannose to the N-glycan precursor skeleton by Alg11 (Saccharomyces cerevisiae)
ALG11 transfers the fourth and fifth Man to the N-glycan precursor (Homo sapiens)
Other forms of this molecule
(GlcNAc)2 (Man)5 (PP-Dol)1 [integral component of lumenal side of endoplasmic reticulum membrane]
Cross References
COMPOUND
C05864
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