Reactome | ezetimibe [extracellular region]

Stable Identifier

R-ALL-265479

Type

ChemicalDrug

Compartment

extracellular region

Synonyms

EZE

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Literature References

PubMed ID	Title	Journal	Year
15928087	The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1) Lisnock, J, Garcia-Calvo, M, Shevell, DE, Iyer, SP, Chapman, KT, Smith, MM, Altmann, SW, Detmers, PA, Ogawa, A, Thornberry, NA, Dean, DC, Bull, HG, Crona, JH, Davis HR, Jr, O'Neill, KA, Graziano, MP, Makarewicz, AM, Braun, MP, Hughes, M, Tang, YS, Hawes, BE, Ujjainwalla, F, Macintyre, DE, Burnett, DA	Proc Natl Acad Sci U S A	2005

External Reference Information

External Reference

ezetimibe [Guide to Pharmacology:6816]

Participates

as an input of

as a component of

Disease

Name	Identifier	Synonyms
familial hypercholesterolemia	DOID:13810	Fredrickson type IIa hyperlipoproteinemia, type II hyperlipidemia, hyperbetalipoproteinemia, familial hypercholesteremia, familial hyperbetalipoproteinaemia, Fredrickson type IIa lipidaemia