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GlcA-β1,3-GlcNAc [lysosomal lumen]
Stable Identifier
R-ALL-2162224
Type
Chemical Compound [SimpleEntity]
Compartment
lysosomal lumen
Synonyms
beta-D-GlcpA-(1->3)-D-GlcpNAc
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Metabolism of carbohydrates and carbohydrate derivatives (Bos taurus)
Glycosaminoglycan metabolism (Bos taurus)
Hyaluronan metabolism (Bos taurus)
Hyaluronan degradation (Bos taurus)
GUSB tetramer hydrolyses (HA)2 (Bos taurus)
(HA)2 [lysosomal lumen]
GlcA-β1,3-GlcNAc [lysosomal lumen]
GUSB tetramer hydrolyzes GlcA-β1,3-GlcNAc (Bos taurus)
GlcA-β1,3-GlcNAc [lysosomal lumen]
HEXA cleaves the terminal GlcNAc from small HA fragments (Bos taurus)
GlcA-β1,3-GlcNAc [lysosomal lumen]
HEXB cleaves the terminal GlcNAc from small HA fragments (Bos taurus)
GlcA-β1,3-GlcNAc [lysosomal lumen]
HYAL1 hydrolyses (HA)50 (Bos taurus)
(HA)2 [lysosomal lumen]
GlcA-β1,3-GlcNAc [lysosomal lumen]
(HA)50 [lysosomal lumen]
GlcA-β1,3-GlcNAc [lysosomal lumen]
Metabolism (Caenorhabditis elegans)
Metabolism of carbohydrates and carbohydrate derivatives (Caenorhabditis elegans)
Glycosaminoglycan metabolism (Caenorhabditis elegans)
Hyaluronan metabolism (Caenorhabditis elegans)
Hyaluronan degradation (Caenorhabditis elegans)
GUSB tetramer hydrolyses (HA)2 (Caenorhabditis elegans)
(HA)2 [lysosomal lumen]
GlcA-β1,3-GlcNAc [lysosomal lumen]
GUSB tetramer hydrolyzes GlcA-β1,3-GlcNAc (Caenorhabditis elegans)
GlcA-β1,3-GlcNAc [lysosomal lumen]
HEXA cleaves the terminal GlcNAc from small HA fragments (Caenorhabditis elegans)
GlcA-β1,3-GlcNAc [lysosomal lumen]
HEXB cleaves the terminal GlcNAc from small HA fragments (Caenorhabditis elegans)
GlcA-β1,3-GlcNAc [lysosomal lumen]
HYAL1 hydrolyses (HA)50 (Caenorhabditis elegans)
(HA)2 [lysosomal lumen]
GlcA-β1,3-GlcNAc [lysosomal lumen]
(HA)50 [lysosomal lumen]
GlcA-β1,3-GlcNAc [lysosomal lumen]
Metabolism (Canis familiaris)
Metabolism of carbohydrates and carbohydrate derivatives (Canis familiaris)
Glycosaminoglycan metabolism (Canis familiaris)
Hyaluronan metabolism (Canis familiaris)
Hyaluronan degradation (Canis familiaris)
GUSB tetramer hydrolyses (HA)2 (Canis familiaris)
(HA)2 [lysosomal lumen]
GlcA-β1,3-GlcNAc [lysosomal lumen]
GUSB tetramer hydrolyzes GlcA-β1,3-GlcNAc (Canis familiaris)
GlcA-β1,3-GlcNAc [lysosomal lumen]
HEXA cleaves the terminal GlcNAc from small HA fragments (Canis familiaris)
GlcA-β1,3-GlcNAc [lysosomal lumen]
HEXB cleaves the terminal GlcNAc from small HA fragments (Canis familiaris)
GlcA-β1,3-GlcNAc [lysosomal lumen]
HYAL1 hydrolyses (HA)50 (Canis familiaris)
(HA)2 [lysosomal lumen]
GlcA-β1,3-GlcNAc [lysosomal lumen]
(HA)50 [lysosomal lumen]
GlcA-β1,3-GlcNAc [lysosomal lumen]
Metabolism (Danio rerio)
Metabolism of carbohydrates and carbohydrate derivatives (Danio rerio)
Glycosaminoglycan metabolism (Danio rerio)
Hyaluronan metabolism (Danio rerio)
Hyaluronan degradation (Danio rerio)
GUSB tetramer hydrolyses (HA)2 (Danio rerio)
(HA)2 [lysosomal lumen]
GlcA-β1,3-GlcNAc [lysosomal lumen]
GUSB tetramer hydrolyzes GlcA-β1,3-GlcNAc (Danio rerio)
GlcA-β1,3-GlcNAc [lysosomal lumen]
HYAL1 hydrolyses (HA)50 (Danio rerio)
(HA)2 [lysosomal lumen]
GlcA-β1,3-GlcNAc [lysosomal lumen]
(HA)50 [lysosomal lumen]
GlcA-β1,3-GlcNAc [lysosomal lumen]
Metabolism (Dictyostelium discoideum)
Metabolism of carbohydrates and carbohydrate derivatives (Dictyostelium discoideum)
Glycosaminoglycan metabolism (Dictyostelium discoideum)
Hyaluronan metabolism (Dictyostelium discoideum)
Hyaluronan degradation (Dictyostelium discoideum)
HEXA cleaves the terminal GlcNAc from small HA fragments (Dictyostelium discoideum)
GlcA-β1,3-GlcNAc [lysosomal lumen]
HEXB cleaves the terminal GlcNAc from small HA fragments (Dictyostelium discoideum)
GlcA-β1,3-GlcNAc [lysosomal lumen]
Metabolism (Drosophila melanogaster)
Metabolism of carbohydrates and carbohydrate derivatives (Drosophila melanogaster)
Glycosaminoglycan metabolism (Drosophila melanogaster)
Hyaluronan metabolism (Drosophila melanogaster)
Hyaluronan degradation (Drosophila melanogaster)
GUSB tetramer hydrolyses (HA)2 (Drosophila melanogaster)
(HA)2 [lysosomal lumen]
GlcA-β1,3-GlcNAc [lysosomal lumen]
GUSB tetramer hydrolyzes GlcA-β1,3-GlcNAc (Drosophila melanogaster)
GlcA-β1,3-GlcNAc [lysosomal lumen]
Metabolism (Gallus gallus)
Metabolism of carbohydrates and carbohydrate derivatives (Gallus gallus)
Glycosaminoglycan metabolism (Gallus gallus)
Hyaluronan metabolism (Gallus gallus)
Hyaluronan degradation (Gallus gallus)
GUSB tetramer hydrolyses (HA)2 (Gallus gallus)
(HA)2 [lysosomal lumen]
GlcA-β1,3-GlcNAc [lysosomal lumen]
GUSB tetramer hydrolyzes GlcA-β1,3-GlcNAc (Gallus gallus)
GlcA-β1,3-GlcNAc [lysosomal lumen]
HEXA cleaves the terminal GlcNAc from small HA fragments (Gallus gallus)
GlcA-β1,3-GlcNAc [lysosomal lumen]
HEXB cleaves the terminal GlcNAc from small HA fragments (Gallus gallus)
GlcA-β1,3-GlcNAc [lysosomal lumen]
HYAL1 hydrolyses (HA)50 (Gallus gallus)
(HA)2 [lysosomal lumen]
GlcA-β1,3-GlcNAc [lysosomal lumen]
(HA)50 [lysosomal lumen]
GlcA-β1,3-GlcNAc [lysosomal lumen]
Disease (Homo sapiens)
Diseases of metabolism (Homo sapiens)
Diseases of carbohydrate metabolism (Homo sapiens)
Mucopolysaccharidoses (Homo sapiens)
MPS IX - Natowicz syndrome (Hyaluronan metabolism) (Homo sapiens)
Defective HYAL1 does not hydrolyse (HA)50 (Homo sapiens)
(HA)50 [lysosomal lumen]
GlcA-β1,3-GlcNAc [lysosomal lumen]
MPS VII - Sly syndrome (Hyaluronan metabolism) (Homo sapiens)
Defective GUSB does not hydrolyse (HA)2 (Homo sapiens)
(HA)2 [lysosomal lumen]
GlcA-β1,3-GlcNAc [lysosomal lumen]
Defective GUSB does not hydrolyse GlcA-β1,3-GlcNAc (Homo sapiens)
GlcA-β1,3-GlcNAc [lysosomal lumen]
Metabolism (Homo sapiens)
Metabolism of carbohydrates and carbohydrate derivatives (Homo sapiens)
Glycosaminoglycan metabolism (Homo sapiens)
Hyaluronan metabolism (Homo sapiens)
Hyaluronan degradation (Homo sapiens)
20kDa HA fragments are translocated to lysosomes (Homo sapiens)
(HA)50 [lysosomal lumen]
GlcA-β1,3-GlcNAc [lysosomal lumen]
GUSB tetramer hydrolyses (HA)2 (Homo sapiens)
(HA)2 [lysosomal lumen]
GlcA-β1,3-GlcNAc [lysosomal lumen]
GUSB tetramer hydrolyzes GlcA-β1,3-GlcNAc (Homo sapiens)
GlcA-β1,3-GlcNAc [lysosomal lumen]
HEXA cleaves the terminal GlcNAc from small HA fragments (Homo sapiens)
GlcA-β1,3-GlcNAc [lysosomal lumen]
HEXB cleaves the terminal GlcNAc from small HA fragments (Homo sapiens)
GlcA-β1,3-GlcNAc [lysosomal lumen]
HYAL1 hydrolyses (HA)50 (Homo sapiens)
(HA)2 [lysosomal lumen]
GlcA-β1,3-GlcNAc [lysosomal lumen]
(HA)50 [lysosomal lumen]
GlcA-β1,3-GlcNAc [lysosomal lumen]
Metabolism (Mus musculus)
Metabolism of carbohydrates and carbohydrate derivatives (Mus musculus)
Glycosaminoglycan metabolism (Mus musculus)
Hyaluronan metabolism (Mus musculus)
Hyaluronan degradation (Mus musculus)
GUSB tetramer hydrolyses (HA)2 (Mus musculus)
(HA)2 [lysosomal lumen]
GlcA-β1,3-GlcNAc [lysosomal lumen]
GUSB tetramer hydrolyzes GlcA-β1,3-GlcNAc (Mus musculus)
GlcA-β1,3-GlcNAc [lysosomal lumen]
HEXA cleaves the terminal GlcNAc from small HA fragments (Mus musculus)
GlcA-β1,3-GlcNAc [lysosomal lumen]
HEXB cleaves the terminal GlcNAc from small HA fragments (Mus musculus)
GlcA-β1,3-GlcNAc [lysosomal lumen]
HYAL1 hydrolyses (HA)50 (Mus musculus)
(HA)2 [lysosomal lumen]
GlcA-β1,3-GlcNAc [lysosomal lumen]
(HA)50 [lysosomal lumen]
GlcA-β1,3-GlcNAc [lysosomal lumen]
Metabolism (Rattus norvegicus)
Metabolism of carbohydrates and carbohydrate derivatives (Rattus norvegicus)
Glycosaminoglycan metabolism (Rattus norvegicus)
Hyaluronan metabolism (Rattus norvegicus)
Hyaluronan degradation (Rattus norvegicus)
GUSB tetramer hydrolyses (HA)2 (Rattus norvegicus)
(HA)2 [lysosomal lumen]
GlcA-β1,3-GlcNAc [lysosomal lumen]
GUSB tetramer hydrolyzes GlcA-β1,3-GlcNAc (Rattus norvegicus)
GlcA-β1,3-GlcNAc [lysosomal lumen]
HEXA cleaves the terminal GlcNAc from small HA fragments (Rattus norvegicus)
GlcA-β1,3-GlcNAc [lysosomal lumen]
HEXB cleaves the terminal GlcNAc from small HA fragments (Rattus norvegicus)
GlcA-β1,3-GlcNAc [lysosomal lumen]
HYAL1 hydrolyses (HA)50 (Rattus norvegicus)
(HA)2 [lysosomal lumen]
GlcA-β1,3-GlcNAc [lysosomal lumen]
(HA)50 [lysosomal lumen]
GlcA-β1,3-GlcNAc [lysosomal lumen]
Metabolism (Sus scrofa)
Metabolism of carbohydrates and carbohydrate derivatives (Sus scrofa)
Glycosaminoglycan metabolism (Sus scrofa)
Hyaluronan metabolism (Sus scrofa)
Hyaluronan degradation (Sus scrofa)
GUSB tetramer hydrolyses (HA)2 (Sus scrofa)
(HA)2 [lysosomal lumen]
GlcA-β1,3-GlcNAc [lysosomal lumen]
GUSB tetramer hydrolyzes GlcA-β1,3-GlcNAc (Sus scrofa)
GlcA-β1,3-GlcNAc [lysosomal lumen]
HEXA cleaves the terminal GlcNAc from small HA fragments (Sus scrofa)
GlcA-β1,3-GlcNAc [lysosomal lumen]
HEXB cleaves the terminal GlcNAc from small HA fragments (Sus scrofa)
GlcA-β1,3-GlcNAc [lysosomal lumen]
HYAL1 hydrolyses (HA)50 (Sus scrofa)
(HA)2 [lysosomal lumen]
GlcA-β1,3-GlcNAc [lysosomal lumen]
(HA)50 [lysosomal lumen]
GlcA-β1,3-GlcNAc [lysosomal lumen]
Metabolism (Xenopus tropicalis)
Metabolism of carbohydrates and carbohydrate derivatives (Xenopus tropicalis)
Glycosaminoglycan metabolism (Xenopus tropicalis)
Hyaluronan metabolism (Xenopus tropicalis)
Hyaluronan degradation (Xenopus tropicalis)
GUSB tetramer hydrolyses (HA)2 (Xenopus tropicalis)
(HA)2 [lysosomal lumen]
GlcA-β1,3-GlcNAc [lysosomal lumen]
GUSB tetramer hydrolyzes GlcA-β1,3-GlcNAc (Xenopus tropicalis)
GlcA-β1,3-GlcNAc [lysosomal lumen]
HEXB cleaves the terminal GlcNAc from small HA fragments (Xenopus tropicalis)
GlcA-β1,3-GlcNAc [lysosomal lumen]
HYAL1 hydrolyses (HA)50 (Xenopus tropicalis)
(HA)2 [lysosomal lumen]
GlcA-β1,3-GlcNAc [lysosomal lumen]
(HA)50 [lysosomal lumen]
GlcA-β1,3-GlcNAc [lysosomal lumen]
External Reference Information
External Reference
beta-D-GlcpA-(1->3)-D-GlcpNAc [ChEBI:64024]
Participates
as an input of
Defective GUSB does not hydrolyse GlcA-β1,3-GlcNAc (Homo sapiens)
GUSB tetramer hydrolyzes GlcA-β1,3-GlcNAc (Caenorhabditis elegans)
GUSB tetramer hydrolyzes GlcA-β1,3-GlcNAc (Drosophila melanogaster)
GUSB tetramer hydrolyzes GlcA-β1,3-GlcNAc (Gallus gallus)
GUSB tetramer hydrolyzes GlcA-β1,3-GlcNAc (Xenopus tropicalis)
GUSB tetramer hydrolyzes GlcA-β1,3-GlcNAc (Danio rerio)
GUSB tetramer hydrolyzes GlcA-β1,3-GlcNAc (Sus scrofa)
GUSB tetramer hydrolyzes GlcA-β1,3-GlcNAc (Canis familiaris)
GUSB tetramer hydrolyzes GlcA-β1,3-GlcNAc (Rattus norvegicus)
GUSB tetramer hydrolyzes GlcA-β1,3-GlcNAc (Mus musculus)
GUSB tetramer hydrolyzes GlcA-β1,3-GlcNAc (Homo sapiens)
GUSB tetramer hydrolyzes GlcA-β1,3-GlcNAc (Bos taurus)
as an output of
HEXA cleaves the terminal GlcNAc from small HA fragments (Dictyostelium discoideum)
HEXA cleaves the terminal GlcNAc from small HA fragments (Caenorhabditis elegans)
HEXA cleaves the terminal GlcNAc from small HA fragments (Gallus gallus)
HEXA cleaves the terminal GlcNAc from small HA fragments (Sus scrofa)
HEXA cleaves the terminal GlcNAc from small HA fragments (Canis familiaris)
HEXA cleaves the terminal GlcNAc from small HA fragments (Rattus norvegicus)
HEXA cleaves the terminal GlcNAc from small HA fragments (Mus musculus)
HEXA cleaves the terminal GlcNAc from small HA fragments (Homo sapiens)
HEXA cleaves the terminal GlcNAc from small HA fragments (Bos taurus)
HEXB cleaves the terminal GlcNAc from small HA fragments (Dictyostelium discoideum)
HEXB cleaves the terminal GlcNAc from small HA fragments (Caenorhabditis elegans)
HEXB cleaves the terminal GlcNAc from small HA fragments (Gallus gallus)
HEXB cleaves the terminal GlcNAc from small HA fragments (Xenopus tropicalis)
HEXB cleaves the terminal GlcNAc from small HA fragments (Sus scrofa)
HEXB cleaves the terminal GlcNAc from small HA fragments (Canis familiaris)
HEXB cleaves the terminal GlcNAc from small HA fragments (Rattus norvegicus)
HEXB cleaves the terminal GlcNAc from small HA fragments (Mus musculus)
HEXB cleaves the terminal GlcNAc from small HA fragments (Homo sapiens)
HEXB cleaves the terminal GlcNAc from small HA fragments (Bos taurus)
as a repeated unit of
(HA)50 [lysosomal lumen]
(HA)2 [lysosomal lumen]
Other forms of this molecule
GlcA-b1,3-GlcNAc [plasma membrane]
GlcA-b1,3-GlcNAc [cytosol]
GlcA-b1,3-GlcNAc [extracellular region]
Cross References
ZINC
ZINC000031371287
,
ZINC000031371284
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