Reactome | TrXA3 [cytosol]

TrXA3 [cytosol]

Stable Identifier

R-ALL-2142713

Type

Chemical Compound [SimpleEntity]

Compartment

cytosol

Synonyms

(5Z,9E,12S,14Z)-8,11,12-trihydroxyicosa-5,9,14-trienoate, Trioxilin A3, (5Z,9E,12S,14Z)-8,11,12-trihydroxyicosa-5,9,14-trienoic acid

Locations in the PathwayBrowser

for Species:

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Metabolism (Bos taurus)

- Biological oxidations (Bos taurus)
  - Phase I - Functionalization of compounds (Bos taurus)
    - Cytochrome P450 - arranged by substrate type (Bos taurus)
      - Eicosanoids (Bos taurus)
        
        CYP4F22 20-hydroxylates TrXA3 (Bos taurus)
        
        TrXA3 [cytosol]

Metabolism (Canis familiaris)

- Biological oxidations (Canis familiaris)
  - Phase I - Functionalization of compounds (Canis familiaris)
    - Cytochrome P450 - arranged by substrate type (Canis familiaris)
      - Eicosanoids (Canis familiaris)
        
        CYP4F22 20-hydroxylates TrXA3 (Canis familiaris)
        
        TrXA3 [cytosol]

Metabolism (Danio rerio)

- Biological oxidations (Danio rerio)
  - Phase I - Functionalization of compounds (Danio rerio)
    - Cytochrome P450 - arranged by substrate type (Danio rerio)
      - Eicosanoids (Danio rerio)
        
        CYP4F22 20-hydroxylates TrXA3 (Danio rerio)
        
        TrXA3 [cytosol]

Metabolism (Homo sapiens)

- Biological oxidations (Homo sapiens)
  - Phase I - Functionalization of compounds (Homo sapiens)
    - Cytochrome P450 - arranged by substrate type (Homo sapiens)
      - Eicosanoids (Homo sapiens)
        
        CYP4F22 20-hydroxylates TrXA3 (Homo sapiens)
        
        TrXA3 [cytosol]
- Metabolism of lipids (Homo sapiens)
  - Fatty acid metabolism (Homo sapiens)
    - Arachidonate metabolism (Homo sapiens)
      - Synthesis of Hepoxilins (HX) and Trioxilins (TrX) (Homo sapiens)
        
        HXA3/B3 is hydrolysed to TrXA3/B3 by HXEH (Homo sapiens)
        
        TrXA3/B3 [cytosol]
        
        TrXA3 [cytosol]

Metabolism (Mus musculus)

- Biological oxidations (Mus musculus)
  - Phase I - Functionalization of compounds (Mus musculus)
    - Cytochrome P450 - arranged by substrate type (Mus musculus)
      - Eicosanoids (Mus musculus)
        
        CYP4F22 20-hydroxylates TrXA3 (Mus musculus)
        
        TrXA3 [cytosol]

Metabolism (Sus scrofa)

- Biological oxidations (Sus scrofa)
  - Phase I - Functionalization of compounds (Sus scrofa)
    - Cytochrome P450 - arranged by substrate type (Sus scrofa)
      - Eicosanoids (Sus scrofa)
        
        CYP4F22 20-hydroxylates TrXA3 (Sus scrofa)
        
        TrXA3 [cytosol]

Metabolism (Xenopus tropicalis)

- Biological oxidations (Xenopus tropicalis)
  - Phase I - Functionalization of compounds (Xenopus tropicalis)
    - Cytochrome P450 - arranged by substrate type (Xenopus tropicalis)
      - Eicosanoids (Xenopus tropicalis)
        
        CYP4F22 20-hydroxylates TrXA3 (Xenopus tropicalis)
        
        TrXA3 [cytosol]

External Reference Information

External Reference

(5Z,9E,12S,14Z)-8,11,12-trihydroxyicosa-5,9,14-trienoate [ChEBI:57448]

Participates

as an input of

as a member of

TrXA3/B3 [cytosol]

Cross References

ZINC

ZINC000013523776, ZINC000014781468, ZINC000038792092, ZINC000038792091

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