Reactome | aliskiren [extracellular region]

aliskiren [extracellular region]

Stable Identifier

R-ALL-2022362

Type

ChemicalDrug

Compartment

extracellular region

Locations in the PathwayBrowser

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External Reference Information

External Reference

aliskiren [Guide to Pharmacology:4812]

This entity regulates

Negatively

Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Gallus gallus)
Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Xenopus tropicalis)
Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Homo sapiens)
Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Gallus gallus)
Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Xenopus tropicalis)
Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Gallus gallus)
Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Xenopus tropicalis)
Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Caenorhabditis elegans)
Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Sus scrofa)
Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Rattus norvegicus)
Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Mus musculus)
Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Caenorhabditis elegans)
Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Sus scrofa)
Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Rattus norvegicus)
Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Mus musculus)
Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Homo sapiens)
Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Caenorhabditis elegans)
Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Sus scrofa)
Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Rattus norvegicus)
Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Mus musculus)
Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Drosophila melanogaster)
Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Bos taurus)
Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Canis familiaris)
Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Drosophila melanogaster)
Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Bos taurus)
Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Canis familiaris)
Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Drosophila melanogaster)
Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Danio rerio)
Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Bos taurus)
Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Canis familiaris)
Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Homo sapiens)

Disease

Name	Identifier	Synonyms
hypertension	DOID:10763	High blood pressure (& [essential hypertension]), HTN, hypertensive disease, hyperpiesia, vascular hypertensive disorder

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