Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
7 alpha-hydroxycholesterol [endoplasmic reticulum membrane]
Stable Identifier
R-ALL-192114
Type
Chemical Compound [SimpleEntity]
Compartment
endoplasmic reticulum membrane
Synonyms
7alpha-hydroxycholesterol
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Canis familiaris
Danio rerio
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Biological oxidations (Bos taurus)
Phase I - Functionalization of compounds (Bos taurus)
Cytochrome P450 - arranged by substrate type (Bos taurus)
Endogenous sterols (Bos taurus)
CYP7A1 7-hydroxylates CHOL (Bos taurus)
7 alpha-hydroxycholesterol [endoplasmic reticulum membrane]
Metabolism of lipids (Bos taurus)
Metabolism of steroids (Bos taurus)
Bile acid and bile salt metabolism (Bos taurus)
Synthesis of bile acids and bile salts (Bos taurus)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Bos taurus)
7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one (Bos taurus)
7 alpha-hydroxycholesterol [endoplasmic reticulum membrane]
CYP7A1 7-hydroxylates CHOL (Bos taurus)
7 alpha-hydroxycholesterol [endoplasmic reticulum membrane]
Metabolism (Canis familiaris)
Biological oxidations (Canis familiaris)
Phase I - Functionalization of compounds (Canis familiaris)
Cytochrome P450 - arranged by substrate type (Canis familiaris)
Endogenous sterols (Canis familiaris)
CYP7A1 7-hydroxylates CHOL (Canis familiaris)
7 alpha-hydroxycholesterol [endoplasmic reticulum membrane]
Metabolism of lipids (Canis familiaris)
Metabolism of steroids (Canis familiaris)
Bile acid and bile salt metabolism (Canis familiaris)
Synthesis of bile acids and bile salts (Canis familiaris)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Canis familiaris)
7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one (Canis familiaris)
7 alpha-hydroxycholesterol [endoplasmic reticulum membrane]
CYP7A1 7-hydroxylates CHOL (Canis familiaris)
7 alpha-hydroxycholesterol [endoplasmic reticulum membrane]
Metabolism (Danio rerio)
Biological oxidations (Danio rerio)
Phase I - Functionalization of compounds (Danio rerio)
Cytochrome P450 - arranged by substrate type (Danio rerio)
Endogenous sterols (Danio rerio)
CYP7A1 7-hydroxylates CHOL (Danio rerio)
7 alpha-hydroxycholesterol [endoplasmic reticulum membrane]
Metabolism of lipids (Danio rerio)
Metabolism of steroids (Danio rerio)
Bile acid and bile salt metabolism (Danio rerio)
Synthesis of bile acids and bile salts (Danio rerio)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Danio rerio)
7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one (Danio rerio)
7 alpha-hydroxycholesterol [endoplasmic reticulum membrane]
CYP7A1 7-hydroxylates CHOL (Danio rerio)
7 alpha-hydroxycholesterol [endoplasmic reticulum membrane]
Metabolism (Drosophila melanogaster)
Metabolism of lipids (Drosophila melanogaster)
Metabolism of steroids (Drosophila melanogaster)
Bile acid and bile salt metabolism (Drosophila melanogaster)
Synthesis of bile acids and bile salts (Drosophila melanogaster)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Drosophila melanogaster)
7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one (Drosophila melanogaster)
7 alpha-hydroxycholesterol [endoplasmic reticulum membrane]
Metabolism (Gallus gallus)
Biological oxidations (Gallus gallus)
Phase I - Functionalization of compounds (Gallus gallus)
Cytochrome P450 - arranged by substrate type (Gallus gallus)
Endogenous sterols (Gallus gallus)
CYP7A1 7-hydroxylates CHOL (Gallus gallus)
7 alpha-hydroxycholesterol [endoplasmic reticulum membrane]
Metabolism of lipids (Gallus gallus)
Metabolism of steroids (Gallus gallus)
Bile acid and bile salt metabolism (Gallus gallus)
Synthesis of bile acids and bile salts (Gallus gallus)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Gallus gallus)
CYP7A1 7-hydroxylates CHOL (Gallus gallus)
7 alpha-hydroxycholesterol [endoplasmic reticulum membrane]
Metabolism (Homo sapiens)
Biological oxidations (Homo sapiens)
Phase I - Functionalization of compounds (Homo sapiens)
Cytochrome P450 - arranged by substrate type (Homo sapiens)
Endogenous sterols (Homo sapiens)
CYP7A1 7-hydroxylates CHOL (Homo sapiens)
7 alpha-hydroxycholesterol [endoplasmic reticulum membrane]
Metabolism of lipids (Homo sapiens)
Metabolism of steroids (Homo sapiens)
Bile acid and bile salt metabolism (Homo sapiens)
Synthesis of bile acids and bile salts (Homo sapiens)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Homo sapiens)
7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one (Homo sapiens)
7 alpha-hydroxycholesterol [endoplasmic reticulum membrane]
CYP7A1 7-hydroxylates CHOL (Homo sapiens)
7 alpha-hydroxycholesterol [endoplasmic reticulum membrane]
Metabolism (Mus musculus)
Biological oxidations (Mus musculus)
Phase I - Functionalization of compounds (Mus musculus)
Cytochrome P450 - arranged by substrate type (Mus musculus)
Endogenous sterols (Mus musculus)
CYP7A1 7-hydroxylates CHOL (Mus musculus)
7 alpha-hydroxycholesterol [endoplasmic reticulum membrane]
Metabolism of lipids (Mus musculus)
Metabolism of steroids (Mus musculus)
Bile acid and bile salt metabolism (Mus musculus)
Synthesis of bile acids and bile salts (Mus musculus)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Mus musculus)
7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one (Mus musculus)
7 alpha-hydroxycholesterol [endoplasmic reticulum membrane]
CYP7A1 7-hydroxylates CHOL (Mus musculus)
7 alpha-hydroxycholesterol [endoplasmic reticulum membrane]
Metabolism (Rattus norvegicus)
Biological oxidations (Rattus norvegicus)
Phase I - Functionalization of compounds (Rattus norvegicus)
Cytochrome P450 - arranged by substrate type (Rattus norvegicus)
Endogenous sterols (Rattus norvegicus)
CYP7A1 7-hydroxylates CHOL (Rattus norvegicus)
7 alpha-hydroxycholesterol [endoplasmic reticulum membrane]
Metabolism of lipids (Rattus norvegicus)
Metabolism of steroids (Rattus norvegicus)
Bile acid and bile salt metabolism (Rattus norvegicus)
Synthesis of bile acids and bile salts (Rattus norvegicus)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Rattus norvegicus)
7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one (Rattus norvegicus)
7 alpha-hydroxycholesterol [endoplasmic reticulum membrane]
CYP7A1 7-hydroxylates CHOL (Rattus norvegicus)
7 alpha-hydroxycholesterol [endoplasmic reticulum membrane]
Metabolism (Sus scrofa)
Biological oxidations (Sus scrofa)
Phase I - Functionalization of compounds (Sus scrofa)
Cytochrome P450 - arranged by substrate type (Sus scrofa)
Endogenous sterols (Sus scrofa)
CYP7A1 7-hydroxylates CHOL (Sus scrofa)
7 alpha-hydroxycholesterol [endoplasmic reticulum membrane]
Metabolism of lipids (Sus scrofa)
Metabolism of steroids (Sus scrofa)
Bile acid and bile salt metabolism (Sus scrofa)
Synthesis of bile acids and bile salts (Sus scrofa)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Sus scrofa)
7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one (Sus scrofa)
7 alpha-hydroxycholesterol [endoplasmic reticulum membrane]
CYP7A1 7-hydroxylates CHOL (Sus scrofa)
7 alpha-hydroxycholesterol [endoplasmic reticulum membrane]
Metabolism (Xenopus tropicalis)
Biological oxidations (Xenopus tropicalis)
Phase I - Functionalization of compounds (Xenopus tropicalis)
Cytochrome P450 - arranged by substrate type (Xenopus tropicalis)
Endogenous sterols (Xenopus tropicalis)
CYP7A1 7-hydroxylates CHOL (Xenopus tropicalis)
7 alpha-hydroxycholesterol [endoplasmic reticulum membrane]
Metabolism of lipids (Xenopus tropicalis)
Metabolism of steroids (Xenopus tropicalis)
Bile acid and bile salt metabolism (Xenopus tropicalis)
Synthesis of bile acids and bile salts (Xenopus tropicalis)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Xenopus tropicalis)
7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one (Xenopus tropicalis)
7 alpha-hydroxycholesterol [endoplasmic reticulum membrane]
CYP7A1 7-hydroxylates CHOL (Xenopus tropicalis)
7 alpha-hydroxycholesterol [endoplasmic reticulum membrane]
External Reference Information
External Reference
7alpha-hydroxycholesterol [ChEBI:17500]
Participates
as an input of
7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one (Drosophila melanogaster)
7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one (Xenopus tropicalis)
7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one (Danio rerio)
7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one (Sus scrofa)
7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one (Bos taurus)
7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one (Canis familiaris)
7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one (Rattus norvegicus)
7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one (Mus musculus)
7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one (Homo sapiens)
as an output of
CYP7A1 7-hydroxylates CHOL (Gallus gallus)
CYP7A1 7-hydroxylates CHOL (Xenopus tropicalis)
CYP7A1 7-hydroxylates CHOL (Danio rerio)
CYP7A1 7-hydroxylates CHOL (Sus scrofa)
CYP7A1 7-hydroxylates CHOL (Bos taurus)
CYP7A1 7-hydroxylates CHOL (Canis familiaris)
CYP7A1 7-hydroxylates CHOL (Rattus norvegicus)
CYP7A1 7-hydroxylates CHOL (Mus musculus)
CYP7A1 7-hydroxylates CHOL (Homo sapiens)
Cross References
Guide to Pharmacology - Ligands
4351
COMPOUND
C03594
HMDB Metabolite
HMDB0001496
ZINC
ZINC000004096158
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text