Reactome | UniProt:Q9Y421 FAM32A

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UniProt:Q9Y421 FAM32A Show undefined attributes

chain	chain:1-112
checksum	7FAF15315E9D580C
comment	FUNCTION Isoform 1, but not isoform 2 or isoform 3, may induce G2 arrest and apoptosis. May also increase cell sensitivity to apoptotic stimuli.SUBCELLULAR LOCATION Expressed in ovary, with isoform 1 being predominant.INDUCTION By etoposide, puromycin or carboplatin.SIMILARITY Belongs to the FAM32 family.
created	[InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53
crossReference	[DatabaseIdentifier:12441684] RefSeq:NP_054796.1 [DatabaseIdentifier:12280860] Pharos - Targets:Q9Y421 [DatabaseIdentifier:12259021] PRO:Q9Y421 [DatabaseIdentifier:12140525] PDB:7W5A [DatabaseIdentifier:12140516] PDB:8C6J [DatabaseIdentifier:12140526] PDB:7W5B [DatabaseIdentifier:12140524] PDB:6QDV [DatabaseIdentifier:12140529] PDB:9FMD [DatabaseIdentifier:12120523] OpenTargets:ENSG00000105058 [DatabaseIdentifier:11836057] HPA:ENSG00000105058-FAM32A [DatabaseIdentifier:11782944] GeneCards:FAM32A [DatabaseIdentifier:11741856] ENSEMBL:ENST00000589852 [DatabaseIdentifier:11741855] ENSEMBL:ENST00000263384 [DatabaseIdentifier:11619156] ENSEMBL:ENSP00000465969 [DatabaseIdentifier:11619157] ENSEMBL:ENSP00000263384 [DatabaseIdentifier:11506163] ENSEMBL:ENSG00000105058
databaseName	UniProt
dbId	229000
description	recommendedName: Protein FAM32A alternativeName: Ovarian tumor-associated gene 12 shortName: OTAG-12
displayName	UniProt:Q9Y421 FAM32A
geneName	FAM32A OTAG12 CGI-144
identifier	Q9Y421
isSequenceChanged	false
keyword	3D-structure Alternative splicing Apoptosis Cell cycle Nucleus Proteomics identification Reference proteome
modified	[InstanceEdit:9983091] Weiser, Joel, 2026-02-20
moleculeType	Protein
name	FAM32A
otherIdentifier	11733033_a_at 16859294 201863_PM_at 201863_at 26017 34833_at 3823614 3823615 3823616 3823617 3823618 3823619 3823620 3823621 3823622 3823623 3823624 8026541 A_23_P50331 GE56262 GO:0003723 GO:0005515 GO:0005634 GO:0005654 GO:0005730 GO:0006915 HMNXSV003005006 HMNXSV003039434 PH_hs_0000483 PH_hs_0030908 TC19000319.hg g7661695_3p_at
physicalEntity	[EntityWithAccessionedSequence:R-HSA-9769598] FAM32A [nucleoplasm] - Homo sapiens
referenceDatabase	[ReferenceDatabase:2] UniProt
referenceGene	[ReferenceDNASequence:12706409] UCSC:Q9Y421 FAM32A [ReferenceDNASequence:12106323] OMIM:614554 FAM32A [ReferenceDNASequence:12085386] NCBI Gene:26017 FAM32A [ReferenceDNASequence:12001293] Monarch:26017 FAM32A [ReferenceDNASequence:11909539] KEGG:hsa:26017 FAM32A [ReferenceDNASequence:11814555] HGNC:24563 FAM32A [ReferenceDNASequence:11431411] dbSNP Gene:26017 FAM32A [ReferenceDNASequence:11406484] CTD Gene:26017 FAM32A [ReferenceDNASequence:11395220] COSMIC - genes:FAM32A FAM32A [ReferenceDNASequence:11371504] BioGPS Gene:26017 FAM32A [ReferenceDNASequence:ensembl:ENSG00000105058] ENSEMBL:ENSG00000105058 FAM32A
referenceTranscript	[ReferenceRNASequence:12623185] RefSeq:NM_014077.4 FAM32A
schemaClass	ReferenceGeneProduct
secondaryIdentifier	FA32A_HUMAN Q9BT02
sequenceLength	112
species	[Species:48887] Homo sapiens
stId	uniprot:Q9Y421
url	http://purl.uniprot.org/uniprot/Q9Y421

Referrals

(interactor)	[UndirectedInteraction:11255257] UniProt:Q9Y421 <-> UniProt:Q8IWA6 (IntAct) [UndirectedInteraction:11147159] UniProt:Q9HCG8 <-> UniProt:Q9Y421 (IntAct)
(referenceEntity)	[EntityWithAccessionedSequence:R-HSA-9769598] FAM32A [nucleoplasm]

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