UniProt:Q9UI09 NDUFA12

chain
  • chain:1-145
checksum C76C7F2F5974AFF9
comment
  • FUNCTION Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.SUBUNIT Complex I is composed of 45 different subunits.INTERACTION The disease is caused by variants affecting the gene represented in this entry.MISCELLANEOUS In NDUFA12-knockout cells, complex I assembly is not affected, probably due to substitution by the NDUFAF2 paralog.SIMILARITY Belongs to the complex I NDUFA12 subunit family.
crossReference
databaseName UniProt
dbId 59865
description
  • recommendedName: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 alternativeName: 13 kDa differentiation-associated protein alternativeName: Complex I-B17.2 shortName: CI-B17.2 shortName: CIB17.2 alternativeName: NADH-ubiquinone oxidoreductase subunit B17.2
displayName UniProt:Q9UI09 NDUFA12
geneName
  • NDUFA12
  • DAP13
identifier Q9UI09
isSequenceChanged false
keyword
  • 3D-structure
  • Acetylation
  • Alternative splicing
  • Disease variant
  • Electron transport
  • Membrane
  • Mitochondrion
  • Mitochondrion inner membrane
  • Primary mitochondrial disease
  • Proteomics identification
  • Reference proteome
  • Respiratory chain
  • Transport
modified [InstanceEdit:9926675] Weiser, Joel, 2024-11-03
moleculeType Protein
name
  • NDUFA12
otherIdentifier
  • 11757589_a_at
  • 16768628
  • 223244_PM_s_at
  • 223244_s_at
  • 3466285
  • 3466290
  • 3466296
  • 3466297
  • 3466302
  • 3466303
  • 3466304
  • 3466305
  • 3466306
  • 3466308
  • 3466309
  • 3466310
  • 3466311
  • 3466312
  • 3466313
  • 3466314
  • 52104_at
  • 55967
  • 7965515
  • A_23_P76557
  • A_33_P3241753
  • GE79864
  • GO:0005515
  • GO:0005739
  • GO:0005743
  • GO:0006091
  • GO:0008137
  • GO:0009060
  • GO:0016020
  • GO:0016491
  • GO:0042775
  • GO:0042776
  • GO:0045271
  • GO:0055085
  • GO:0055086
  • GO:1901135
  • GO:1902600
  • HMNXSV003006229
  • ILMN_1737738
  • PH_hs_0028878
  • TC12001827.hg
  • TC12003014.hg
  • U34343_at
  • g9651636_3p_s_at
physicalEntity
referenceDatabase [ReferenceDatabase:2] UniProt
referenceGene
referenceTranscript
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • NDUAC_HUMAN
  • F8VQS7
  • Q53XX0
  • Q9BRV6
sequenceLength 145
species [Species:48887] Homo sapiens
stId uniprot:Q9UI09
url http://purl.uniprot.org/uniprot/Q9UI09

Referrals

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