UniProt:Q9HBX9 RXFP1

chain
  • chain:1-757
checksum B32DD71B1A5D5864
comment
  • FUNCTION Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP.SUBUNIT Interacts with C1QTNF8.INTERACTION Expressed in the brain, kidney, testis, placenta, uterus, ovary, adrenal, prostate, skin and heart. Not detected in spleen.SIMILARITY Belongs to the G-protein coupled receptor 1 family.
crossReference
databaseName UniProt
dbId 58539
description
  • recommendedName: Relaxin receptor 1 alternativeName: Leucine-rich repeat-containing G-protein coupled receptor 7 alternativeName: Relaxin family peptide receptor 1
displayName UniProt:Q9HBX9 RXFP1
geneName
  • RXFP1
  • LGR7
identifier Q9HBX9
isSequenceChanged false
keyword
  • 3D-structure
  • Alternative splicing
  • Calcium
  • Cell membrane
  • Disulfide bond
  • G-protein coupled receptor
  • Glycoprotein
  • Leucine-rich repeat
  • Membrane
  • Metal-binding
  • Proteomics identification
  • Receptor
  • Reference proteome
  • Repeat
  • Transducer
  • Transmembrane
  • Transmembrane helix
modified [InstanceEdit:9926675] Weiser, Joel, 2024-11-03
moleculeType Protein
name
  • RXFP1
otherIdentifier
  • 11748207_a_at
  • 11750399_a_at
  • 11750990_a_at
  • 11761923_a_at
  • 1552715_PM_a_at
  • 1552715_a_at
  • 16971910
  • 231804_PM_at
  • 231804_at
  • 238206_PM_at
  • 238206_at
  • 2749485
  • 2749494
  • 2749505
  • 2749507
  • 2749508
  • 2749520
  • 2749523
  • 2749524
  • 2749525
  • 2749526
  • 2749528
  • 2749529
  • 2749530
  • 2749531
  • 2749532
  • 2749533
  • 2749534
  • 2749535
  • 2749536
  • 2749537
  • 2749540
  • 2749541
  • 2749542
  • 2749543
  • 2749544
  • 2749545
  • 2749546
  • 2749547
  • 2749548
  • 2749549
  • 2749550
  • 59350
  • 59756_at
  • 79637_at
  • 8098060
  • 89447_at
  • A_14_P122746
  • A_23_P124534
  • A_23_P433050
  • GE61468
  • GE717026
  • GE80549
  • GO:0004930
  • GO:0005515
  • GO:0005886
  • GO:0007165
  • GO:0007186
  • GO:0007188
  • GO:0007189
  • GO:0007567
  • GO:0008528
  • GO:0009755
  • GO:0016020
  • GO:0022414
  • GO:0030198
  • GO:0036446
  • GO:0042562
  • GO:0046872
  • GO:0048856
  • GO:0060427
  • GO:0060658
  • HMNXSV003010120
  • HMNXSV003017032
  • HMNXSV003021334
  • Hs.179243.0.A1_3p_at
  • Hs.209446.0.S2_3p_at
  • Hs2.209446.1.S1_3p_s_at
  • ILMN_1749150
  • PH_hs_0022861
  • TC04000804.hg
physicalEntity
referenceDatabase [ReferenceDatabase:2] UniProt
referenceGene
referenceTranscript
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • RXFP1_HUMAN
  • B4DHD1
  • B4DTV2
  • Q2M215
  • Q3KU24
  • Q3KU25
  • Q3KU26
sequenceLength 757
species [Species:48887] Homo sapiens
stId uniprot:Q9HBX9
url http://purl.uniprot.org/uniprot/Q9HBX9
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