UniProt:Q9HBI1 PARVB

chain
  • chain:1-364
checksum 4BA4B50C83083DC7
comment
  • FUNCTION Adapter protein that plays a role in integrin signaling via ILK and in activation of the GTPases CDC42 and RAC1 by guanine exchange factors, such as ARHGEF6. Is involved in the reorganization of the actin cytoskeleton and formation of lamellipodia. Plays a role in cell adhesion, cell spreading, establishment or maintenance of cell polarity, and cell migration.SUBUNIT Interacts with DYSF. Interacts with ILK, ARHGEF6, PXN (via LD motifs), ACTN2 and actin.INTERACTION Constituent of focal adhesions. Detected at the tips of the leading edge of cells. Colocalizes with F-actin at the tips of lamellipodia.ALTERNATIVE PRODUCTS Expressed predominantly in heart and skeletal muscle.SIMILARITY Belongs to the parvin family.
crossReference
databaseName UniProt
dbId 61320
description
  • recommendedName: Beta-parvin alternativeName: Affixin
displayName UniProt:Q9HBI1 PARVB
geneName
  • PARVB
  • CGI-56
identifier Q9HBI1
isSequenceChanged false
keyword
  • 3D-structure
  • Actin-binding
  • Alternative splicing
  • Cell adhesion
  • Cell junction
  • Cell membrane
  • Cell projection
  • Cytoplasm
  • Cytoskeleton
  • Membrane
  • Phosphoprotein
  • Proteomics identification
  • Reference proteome
  • Repeat
modified [InstanceEdit:9926675] Weiser, Joel, 2024-11-03
moleculeType Protein
name
  • PARVB
otherIdentifier
  • 11726654_a_at
  • 16931040
  • 204629_PM_at
  • 204629_at
  • 216253_PM_s_at
  • 216253_s_at
  • 229822_PM_at
  • 229822_at
  • 29780
  • 37965_PM_at
  • 37965_at
  • 37966_3p_at
  • 37966_PM_at
  • 37966_at
  • 3947873
  • 3947874
  • 3947875
  • 3947877
  • 3947878
  • 3947887
  • 3947888
  • 3947889
  • 3947892
  • 3947901
  • 3947903
  • 3947904
  • 3947906
  • 3947907
  • 3947913
  • 3947914
  • 3947915
  • 3947919
  • 3947924
  • 3947926
  • 3947927
  • 3947928
  • 3947929
  • 3947932
  • 3947935
  • 3947937
  • 3947938
  • 3947942
  • 3947945
  • 3947946
  • 3947947
  • 3948046
  • 3948048
  • 3948049
  • 3948050
  • 3948051
  • 3948052
  • 4876811C_3p_x_at
  • 4876812C_3p_at
  • 4876812C_3p_x_at
  • 63011_at
  • 8073662
  • A_14_P139219
  • A_23_P40718
  • A_24_P918762
  • A_33_P3413404
  • GE508893
  • GE52968
  • GO:0003779
  • GO:0005515
  • GO:0005737
  • GO:0005829
  • GO:0005856
  • GO:0005886
  • GO:0005925
  • GO:0007155
  • GO:0007163
  • GO:0008092
  • GO:0015629
  • GO:0016020
  • GO:0030017
  • GO:0030018
  • GO:0030027
  • GO:0030031
  • GO:0030032
  • GO:0030036
  • GO:0034446
  • GO:0042995
  • GO:0070161
  • GO:0071963
  • GO:0120031
  • HMNXSV003028809
  • HMNXSV003035460
  • Hs.9344.0.S1_3p_at
  • ILMN_1667592
  • ILMN_1676173
  • ILMN_1787919
  • PH_hs_0000932
  • PH_hs_0030971
  • TC22000370.hg
  • g7019346_3p_at
  • g7019346_3p_x_at
physicalEntity
referenceDatabase [ReferenceDatabase:2] UniProt
referenceGene
referenceTranscript
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • PARVB_HUMAN
  • B0QYM8
  • B0QYN1
  • B2R9X6
  • Q5TGJ5
  • Q86X93
  • Q96PN1
  • Q9NSP7
  • Q9UGT3
  • Q9Y368
  • Q9Y3L6
  • Q9Y3L7
sequenceLength 364
species [Species:48887] Homo sapiens
stId uniprot:Q9HBI1
url http://purl.uniprot.org/uniprot/Q9HBI1
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