UniProt:Q9H9F9 ACTR5

chain
  • chain:1-607
checksum DA3E50AE37BCC363
comment
  • FUNCTION Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. Involved in DNA double-strand break repair and UV-damage excision repair.SUBUNIT Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the helicase ATP-binding and the helicase C-terminal domain of INO80. Interacts with DDB1. Interacts with ACTR8; the interaction is observed in asynchronous (interphase) cells but not in metaphase-arrested cells indicative for a possible dissociation of the INO80 complex in mitotic cells.INTERACTION Predominantly nuclear but undergoes nucleo-cytoplasmic shuttling (PubMed:19014934). Localized to interphase nuclei, but not nucleoli; excluded from chromosomes as mitosis progresses (PubMed:18163988).SIMILARITY Belongs to the actin family. ARP5 subfamily.
created [InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53
crossReference
databaseName UniProt
dbId 219242
description
  • recommendedName: Actin-related protein 5 shortName: hARP5 alternativeName: Sarcoma antigen NY-SAR-16
displayName UniProt:Q9H9F9 ACTR5
geneName
  • ACTR5
  • ARP5
identifier Q9H9F9
isSequenceChanged false
keyword
  • 3D-structure
  • Coiled coil
  • Cytoplasm
  • DNA damage
  • DNA recombination
  • DNA repair
  • Isopeptide bond
  • Nucleus
  • Proteomics identification
  • Reference proteome
  • Transcription
  • Transcription regulation
  • Ubl conjugation
modified [InstanceEdit:9926675] Weiser, Joel, 2024-11-03
moleculeType Protein
name
  • ACTR5
otherIdentifier
  • 11727934_at
  • 16913653
  • 219623_PM_at
  • 219623_at
  • 222147_PM_s_at
  • 222147_s_at
  • 3884802
  • 3884803
  • 3884804
  • 3884805
  • 3884807
  • 3884810
  • 3884811
  • 3884813
  • 3884819
  • 3884820
  • 3884822
  • 3884823
  • 3884824
  • 48398_at
  • 79913
  • 8062545
  • A_14_P129751
  • A_23_P165952
  • GE82964
  • GO:0000723
  • GO:0005515
  • GO:0005634
  • GO:0005654
  • GO:0005737
  • GO:0006259
  • GO:0006275
  • GO:0006281
  • GO:0006282
  • GO:0006302
  • GO:0006310
  • GO:0006325
  • GO:0006338
  • GO:0006355
  • GO:0006974
  • GO:0010604
  • GO:0031011
  • GO:0032200
  • GO:0033044
  • GO:0045739
  • GO:0045893
  • GO:0045935
  • GO:0045995
  • GO:0051052
  • GO:0051726
  • GO:0060382
  • GO:0070914
  • GO:1904507
  • HMNXSV003001475
  • HMNXSV003049771
  • Hs.302092.0.S1_3p_s_at
  • ILMN_1652594
  • PH_hs_0017880
  • TC20000289.hg
  • g13376281_3p_at
physicalEntity
referenceDatabase [ReferenceDatabase:2] UniProt
referenceGene
referenceTranscript
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • ARP5_HUMAN
  • Q86WF7
  • Q8IUY5
  • Q8N724
  • Q9BRN0
  • Q9BVB7
sequenceLength 607
species [Species:48887] Homo sapiens
stId uniprot:Q9H9F9
url http://purl.uniprot.org/uniprot/Q9H9F9
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