UniProt:Q9BUD6 SPON2

chain
  • signal peptide:1-26
  • chain:27-331
checksum 3ABB49FEC45579EC
comment
  • FUNCTION Cell adhesion protein that promotes adhesion and outgrowth of hippocampal embryonic neurons. Binds directly to bacteria and their components and functions as an opsonin for macrophage phagocytosis of bacteria. Essential in the initiation of the innate immune response and represents a unique pattern-recognition molecule in the ECM for microbial pathogens (By similarity). Binds bacterial lipopolysaccharide (LPS).SUBUNIT Monomer. Interacts with integrin.INTERACTION Expressed in normal lung tissue but not in lung carcinoma cell lines.
created [InstanceEdit:143527] Schmidt, EE, 2004-11-12 07:45:10
crossReference
databaseName UniProt
dbId 154300
description
  • recommendedName: Spondin-2 alternativeName: Differentially expressed in cancerous and non-cancerous lung cells 1 shortName: DIL-1 alternativeName: Mindin
displayName UniProt:Q9BUD6 SPON2
geneName
  • SPON2
  • DIL1
  • UNQ435/PRO866
identifier Q9BUD6
isSequenceChanged false
keyword
  • 3D-structure
  • Calcium
  • Cell adhesion
  • Direct protein sequencing
  • Disulfide bond
  • Extracellular matrix
  • Glycoprotein
  • Immunity
  • Innate immunity
  • Metal-binding
  • Proteomics identification
  • Reference proteome
  • Secreted
  • Signal
modified [InstanceEdit:9926675] Weiser, Joel, 2024-11-03
moleculeType Protein
name
  • SPON2
otherIdentifier
  • 10417
  • 11716525_a_at
  • 11716526_x_at
  • 11754601_s_at
  • 11755685_s_at
  • 1569496_PM_s_at
  • 1569496_s_at
  • 218638_PM_s_at
  • 218638_s_at
  • 2756967
  • 2756968
  • 2756969
  • 2756970
  • 2756976
  • 2756977
  • 2756978
  • 2756979
  • 2756980
  • 2756981
  • 2756982
  • 2756983
  • 2756984
  • 2756985
  • 2756986
  • 2756987
  • 2756988
  • 2756989
  • 2757001
  • 2757002
  • 2757004
  • 2757005
  • 2757006
  • 2757007
  • 2757014
  • 2757015
  • 2757017
  • 2757018
  • 2757019
  • 2757020
  • 2757022
  • 2757030
  • 2757032
  • 2757033
  • 52576_s_at
  • 63361_at
  • 8098870
  • A_23_P121533
  • A_33_P3416124
  • GE510351
  • GE58498
  • GO:0001530
  • GO:0002376
  • GO:0002448
  • GO:0003823
  • GO:0005515
  • GO:0005576
  • GO:0005615
  • GO:0007155
  • GO:0008228
  • GO:0008289
  • GO:0030312
  • GO:0031012
  • GO:0032496
  • GO:0032755
  • GO:0032760
  • GO:0042742
  • GO:0043152
  • GO:0045087
  • GO:0046872
  • GO:0050832
  • GO:0051607
  • GO:0060907
  • GO:0070062
  • GO:0071222
  • GO:0098542
  • HMNXSV003034003
  • HMNXSV003048251
  • Hs2.382136.1.S1_3p_s_at
  • ILMN_1676099
  • PH_hs_0033049
  • TC04002414.hg
  • g6912681_3p_s_at
  • p25296
  • p26247
physicalEntity
referenceDatabase [ReferenceDatabase:2] UniProt
referenceGene
referenceTranscript
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • SPON2_HUMAN
  • D3DVN9
  • Q4W5N4
  • Q9ULW1
sequenceLength 331
species [Species:48887] Homo sapiens
stId uniprot:Q9BUD6
url http://purl.uniprot.org/uniprot/Q9BUD6
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