Reactome | UniProt:Q99983 OMD

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UniProt:Q99983 OMD Show undefined attributes

chain	signal peptide:1-20 chain:21-421
checksum	CED47B2BC33BB872
comment	FUNCTION May be implicated in biomineralization processes. Has a function in binding of osteoblasts via the alpha(V)beta(3)-integrin.SUBUNIT Binds the alpha(V)beta(3)-integrin.SUBCELLULAR LOCATION Bone specific.PTM Glycosylated; contains keratan sulfate.SIMILARITY Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
crossReference	[DatabaseIdentifier:12304493] RefSeq:NP_005005.1 [DatabaseIdentifier:12279476] Pharos - Targets:Q99983 [DatabaseIdentifier:12235972] PRO:Q99983 [DatabaseIdentifier:12140049] PDB:5YQ5 [DatabaseIdentifier:12119136] OpenTargets:ENSG00000127083 [DatabaseIdentifier:11834689] HPA:ENSG00000127083-OMD [DatabaseIdentifier:11829016] HMDB Protein:HMDBP10801 [DatabaseIdentifier:11781561] GeneCards:OMD [DatabaseIdentifier:11650415] ENSEMBL:ENST00000707247 [DatabaseIdentifier:11650414] ENSEMBL:ENST00000375550 [DatabaseIdentifier:11527715] ENSEMBL:ENSP00000364700 [DatabaseIdentifier:11527716] ENSEMBL:ENSP00000516806 [DatabaseIdentifier:11442368] ENSEMBL:ENSG00000291355 [DatabaseIdentifier:11442367] ENSEMBL:ENSG00000127083
databaseName	UniProt
dbId	60920
description	recommendedName: Osteomodulin alternativeName: Keratan sulfate proteoglycan osteomodulin shortName: KSPG osteomodulin alternativeName: Osteoadherin shortName: OSAD
displayName	UniProt:Q99983 OMD
geneName	OMD SLRR2C UNQ190/PRO216
identifier	Q99983
isSequenceChanged	false
keyword	3D-structure Cell adhesion Disulfide bond Extracellular matrix Glycoprotein Leucine-rich repeat Proteoglycan Proteomics identification Reference proteome Repeat Secreted Signal Sulfation
modified	[InstanceEdit:9926675] Weiser, Joel, 2024-11-03
moleculeType	Protein
name	OMD
otherIdentifier	11728327_at 11728328_at 17095882 205907_PM_s_at 205907_s_at 205908_PM_s_at 205908_s_at 3214820 3214821 3214823 3214824 3214826 3214827 3214828 3214829 3214830 3214831 3214834 41031_at 4958 8162388 AB000114_at A_23_P94397 GE53008 GO:0005515 GO:0005576 GO:0005615 GO:0005796 GO:0007155 GO:0030312 GO:0031012 GO:0043202 GO:0070062 HMNXSV003044661 Hs.94070.0.S1_3p_a_at ILMN_1749846 PH_hs_0005164 TC09001335.hg g4826875_3p_a_at
physicalEntity	[EntityWithAccessionedSequence:R-HSA-2105004] OMD [lysosomal lumen] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-2046273] N-glycan OMD [Golgi lumen] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-2046255] Gal-glycan OMD [Golgi lumen] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-2046186] Keratan(1)-OMD [Golgi lumen] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-2046196] Keratan(2)-OMD [Golgi lumen] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-2046231] Keratan(3)-OMD [Golgi lumen] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-2046147] Keratan(4)-OMD [Golgi lumen] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-2046264] KS(1)-OMD [Golgi lumen] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-2046188] KS(2)-OMD [Golgi lumen] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-2046240] KS(2)-OMD [lysosomal lumen] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-2046148] KS(2)-OMD [extracellular region] - Homo sapiens
referenceDatabase	[ReferenceDatabase:2] UniProt
referenceGene	[ReferenceDNASequence:12720353] UCSC:Q99983 OMD [ReferenceDNASequence:12105064] OMIM:618926 OMD [ReferenceDNASequence:12021780] NCBI Gene:4958 OMD [ReferenceDNASequence:11937687] Monarch:4958 OMD [ReferenceDNASequence:11851726] KEGG:hsa:4958 OMD [ReferenceDNASequence:11813161] HGNC:8134 OMD [ReferenceDNASequence:11433734] dbSNP Gene:4958 OMD [ReferenceDNASequence:11404672] CTD Gene:4958 OMD [ReferenceDNASequence:11397104] COSMIC - genes:OMD OMD [ReferenceDNASequence:11307898] BioGPS Gene:4958 OMD [ReferenceDNASequence:ensembl:ENSG00000127083] ENSEMBL:ENSG00000127083 OMD
schemaClass	ReferenceGeneProduct
secondaryIdentifier	OMD_HUMAN Q5TBF4
sequenceLength	421
species	[Species:48887] Homo sapiens
stId	uniprot:Q99983
url	http://purl.uniprot.org/uniprot/Q99983

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