Reactome | UniProt:Q96PE2 ARHGEF17

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UniProt:Q96PE2 ARHGEF17 Show undefined attributes

chain	chain:1-2063
checksum	76A53FF6CBF5F5C0
comment	FUNCTION Acts as a guanine nucleotide exchange factor (GEF) for RhoA GTPases.INTERACTION Highly expressed in the heart.ONLINE INFORMATION ARHGEF17
created	[InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53
crossReference	[DatabaseIdentifier:12400655] RefSeq:NP_055601.2 [DatabaseIdentifier:12281348] Pharos - Targets:Q96PE2 [DatabaseIdentifier:12238780] PRO:Q96PE2 [DatabaseIdentifier:12121014] OpenTargets:ENSG00000110237 [DatabaseIdentifier:11836539] HPA:ENSG00000110237-ARHGEF17 [DatabaseIdentifier:11830924] HMDB Protein:HMDBP11505 [DatabaseIdentifier:11783429] GeneCards:ARHGEF17 [DatabaseIdentifier:11713643] ENSEMBL:ENST00000263674 [DatabaseIdentifier:11590944] ENSEMBL:ENSP00000263674 [DatabaseIdentifier:11486718] ENSEMBL:ENSG00000110237
databaseName	UniProt
dbId	219046
description	recommendedName: Rho guanine nucleotide exchange factor 17 alternativeName: 164 kDa Rho-specific guanine-nucleotide exchange factor shortName: p164-RhoGEF shortName: p164RhoGEF alternativeName: Tumor endothelial marker 4
displayName	UniProt:Q96PE2 ARHGEF17
geneName	ARHGEF17 KIAA0337 TEM4
identifier	Q96PE2
isSequenceChanged	false
keyword	Guanine-nucleotide releasing factor Phosphoprotein Proteomics identification Reference proteome
modified	[InstanceEdit:9926675] Weiser, Joel, 2024-11-03
moleculeType	Protein
name	ARHGEF17
otherIdentifier	11720521_at 16728802 203756_PM_at 203756_at 3339813 3339814 3339815 3339816 3339817 3339818 3339819 3339832 3339833 3339834 3339835 3339837 3339841 3339842 3339843 3339844 3339845 3339846 3339847 3339848 3339849 3339850 3339851 3339852 3339854 3339855 3339856 3339857 3339858 3339859 3339860 3339861 3339862 3339863 3339864 3339865 3339866 3339867 3339868 3339869 3339870 3339871 3339872 3339873 3339874 3339879 36025_at 7942417 9828 A_14_P124952 A_23_P76015 A_24_P196413 GE53064 GO:0005085 GO:0005515 GO:0005737 GO:0005829 GO:0030036 GO:0051056 HMNXSV003005506 ILMN_1754562 PH_hs_0003269 TC11000774.hg TC11002781.hg g7662063_3p_at
physicalEntity	[EntityWithAccessionedSequence:R-HSA-194925] ARHGEF17 [cytosol] - Homo sapiens
referenceDatabase	[ReferenceDatabase:2] UniProt
referenceGene	[ReferenceDNASequence:12696477] UCSC:Q96PE2 ARHGEF17 [ReferenceDNASequence:12065868] NCBI Gene:9828 ARHGEF17 [ReferenceDNASequence:11981775] Monarch:9828 ARHGEF17 [ReferenceDNASequence:11891723] KEGG:hsa:9828 ARHGEF17 [ReferenceDNASequence:11815046] HGNC:21726 ARHGEF17 [ReferenceDNASequence:11429844] dbSNP Gene:9828 ARHGEF17 [ReferenceDNASequence:11407085] CTD Gene:9828 ARHGEF17 [ReferenceDNASequence:11393837] COSMIC - genes:ARHGEF17 ARHGEF17 [ReferenceDNASequence:11351986] BioGPS Gene:9828 ARHGEF17 [ReferenceDNASequence:ensembl:ENSG00000110237] ENSEMBL:ENSG00000110237 ARHGEF17
referenceTranscript	[ReferenceRNASequence:12582387] RefSeq:NM_014786.3 ARHGEF17
schemaClass	ReferenceGeneProduct
secondaryIdentifier	ARHGH_HUMAN B2RP20 Q86XU2 Q8N2S0 Q9Y4G3
sequenceLength	2063
species	[Species:48887] Homo sapiens
stId	uniprot:Q96PE2
url	http://purl.uniprot.org/uniprot/Q96PE2

Referrals

(interactor)	[UndirectedInteraction:11243767] UniProt:P61981 <-> UniProt:Q96PE2 (IntAct) [UndirectedInteraction:11139373] UniProt:P31946 <-> UniProt:Q96PE2 (IntAct)
(referenceEntity)	[EntityWithAccessionedSequence:R-HSA-194925] ARHGEF17 [cytosol]