FUNCTION Required for proper chromosome biorientation through the detection or correction of syntelic attachments in mitotic spindles.SUBUNIT Component of the SET1B complex composed of the catalytic subunit SETD1B, WDR5, WDR82, RBBP5, ASH2L/ASH2, CXXC1/CFP1, HCFC1, DPY30 homotrimer and BOD1.INTERACTION Localizes at the centrosomes throughout the cell cycle, only dissociating during cytokinesis. Localizes at the kinetochore from prometaphase until anaphase.ALTERNATIVE PRODUCTS Belongs to the BOD1 family.
recommendedName: Biorientation of chromosomes in cell division protein 1 alternativeName: Biorientation defective protein 1 alternativeName: Protein FAM44B
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice.