Reactome | UniProt:Q96B33 CLDN23

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UniProt:Q96B33 CLDN23 Show undefined attributes

chain	chain:1-292
checksum	D383B139905B8884
comment	FUNCTION Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.INTERACTION Expressed in germinal center B-cells, placenta, stomach as well as in colon tumor.SIMILARITY Belongs to the claudin family.
created	[InstanceEdit:143527] Schmidt, EE, 2004-11-12 07:45:10
crossReference	[DatabaseIdentifier:12472127] RefSeq:NP_919260.2 [DatabaseIdentifier:12289898] Pharos - Targets:Q96B33 [DatabaseIdentifier:12272158] PRO:Q96B33 [DatabaseIdentifier:12129687] OpenTargets:ENSG00000253958 [DatabaseIdentifier:11845047] HPA:ENSG00000253958-CLDN23 [DatabaseIdentifier:11833990] HMDB Protein:HMDBP07606 [DatabaseIdentifier:11792053] GeneCards:CLDN23 [DatabaseIdentifier:11763345] ENSEMBL:ENST00000519106 [DatabaseIdentifier:11763344] ENSEMBL:ENST00000644143 [DatabaseIdentifier:11640645] ENSEMBL:ENSP00000428780 [DatabaseIdentifier:11640646] ENSEMBL:ENSP00000495091 [DatabaseIdentifier:11521270] ENSEMBL:ENSG00000253958 [DatabaseIdentifier:11521271] ENSEMBL:ENSG00000285098
databaseName	UniProt
dbId	145560
description	recommendedName: Claudin-23
displayName	UniProt:Q96B33 CLDN23
geneName	CLDN23
identifier	Q96B33
isSequenceChanged	false
keyword	Cell junction Cell membrane Membrane Proteomics identification Reference proteome Tight junction Transmembrane Transmembrane helix
modified	[InstanceEdit:9926675] Weiser, Joel, 2024-11-03
moleculeType	Protein
name	CLDN23
otherIdentifier	11728603_a_at 137075 17065513 228706_PM_s_at 228706_s_at 228707_PM_at 228707_at 3084969 3084970 3084971 3084972 3084973 3084974 3084975 3084976 71204_at 8144505 ADDON002801.hg A_14_P128652 A_23_P134854 GE79410 GO:0005198 GO:0005515 GO:0005886 GO:0005923 GO:0007155 GO:0016020 GO:0016338 GO:0034330 GO:0042802 GO:0070161 GO:0070830 HMNXSV003055677 Hs.183617.1.A1_3p_at ILMN_1725338 PH_hs_0029367 TC08000059.hg TC08001787.hg
physicalEntity	[EntityWithAccessionedSequence:R-HSA-432979] CLDN23 [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-434614] CLDN23 [cell junction] - Homo sapiens
referenceDatabase	[ReferenceDatabase:2] UniProt
referenceGene	[ReferenceDNASequence:12715821] UCSC:Q96B33 CLDN23 [ReferenceDNASequence:12114313] OMIM:609203 CLDN23 [ReferenceDNASequence:12099039] NCBI Gene:137075 CLDN23 [ReferenceDNASequence:12014946] Monarch:137075 CLDN23 [ReferenceDNASequence:11921727] KEGG:hsa:137075 CLDN23 [ReferenceDNASequence:11823731] HGNC:17591 CLDN23 [ReferenceDNASequence:11432824] dbSNP Gene:137075 CLDN23 [ReferenceDNASequence:11420019] CTD Gene:137075 CLDN23 [ReferenceDNASequence:11396388] COSMIC - genes:CLDN23 CLDN23 [ReferenceDNASequence:11385157] BioGPS Gene:137075 CLDN23 [ReferenceDNASequence:ensembl:ENSG00000253958] ENSEMBL:ENSG00000253958 CLDN23
referenceTranscript	[ReferenceRNASequence:12653601] RefSeq:NM_194284.3 CLDN23
schemaClass	ReferenceGeneProduct
secondaryIdentifier	CLD23_HUMAN Q08AJ3
sequenceLength	292
species	[Species:48887] Homo sapiens
stId	uniprot:Q96B33
url	http://purl.uniprot.org/uniprot/Q96B33

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