UniProt:Q96A65 EXOC4

chain
  • initiator methionine:1
  • chain:2-974
checksum 122CD929C2635786
comment
  • FUNCTION Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.SUBUNIT The exocyst complex is composed of EXOC1, EXOC2, EXOC3, EXOC4, EXOC5, EXOC6, EXOC7 and EXOC8 (By similarity). Interacts with BIRC6/bruce (PubMed:18329369). Interacts with MYRIP (By similarity). Interacts with SH3BP1; required for the localization of both SH3BP1 and the exocyst to the leading edge of migrating cells (PubMed:21658605). Interacts with SLC6A9 (By similarity).INTERACTION Colocalizes with CNTRL/centriolin at the midbody ring (PubMed:16213214). Localizes at the leading edge of migrating cells (By similarity).ALTERNATIVE PRODUCTS Belongs to the SEC8 family.
crossReference
databaseName UniProt
dbId 64256
description
  • recommendedName: Exocyst complex component 4 alternativeName: Exocyst complex component Sec8
displayName UniProt:Q96A65 EXOC4
geneName
  • EXOC4
  • KIAA1699
  • SEC8
  • SEC8L1
identifier Q96A65
isSequenceChanged false
keyword
  • 3D-structure
  • Acetylation
  • Alternative splicing
  • Cell projection
  • Coiled coil
  • Cytoplasm
  • Cytoskeleton
  • Direct protein sequencing
  • Exocytosis
  • Phosphoprotein
  • Protein transport
  • Proteomics identification
  • Reference proteome
  • Transport
modified [InstanceEdit:9963647] Weiser, Joel, 2025-08-15
moleculeType Protein
name
  • EXOC4
physicalEntity
referenceDatabase [ReferenceDatabase:2] UniProt
referenceGene
referenceTranscript
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • EXOC4_HUMAN
  • E9PED2
  • Q541U8
  • Q9C0G4
  • Q9H9K0
  • Q9P102
sequenceLength 974
species [Species:48887] Homo sapiens
stId uniprot:Q96A65
url http://purl.uniprot.org/uniprot/Q96A65

Referrals

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