Reactome | UniProt:Q92966 SNAPC3

chain	chain:1-411
checksum	920584BE4CFA366A
comment	FUNCTION Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.SUBUNIT Part of the SNAPc complex composed of 5 subunits: SNAPC1, SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC3 interacts with SNAPC1.INTERACTION Belongs to the SNAPC3/SRD2 family.
crossReference	[DatabaseIdentifier:12467382] RefSeq:NP_001034786.1 [DatabaseIdentifier:11519329] ENSEMBL:ENSG00000164975 [DatabaseIdentifier:11637572] ENSEMBL:ENSP00000483273 [DatabaseIdentifier:11637573] ENSEMBL:ENSP00000370200 [DatabaseIdentifier:11637570] ENSEMBL:ENSP00000436699 [DatabaseIdentifier:11637571] ENSEMBL:ENSP00000432393 [DatabaseIdentifier:11760269] ENSEMBL:ENST00000490969 [DatabaseIdentifier:11760271] ENSEMBL:ENST00000380821 [DatabaseIdentifier:11760272] ENSEMBL:ENST00000610884 [DatabaseIdentifier:11760270] ENSEMBL:ENST00000467062 [DatabaseIdentifier:11790588] GeneCards:SNAPC3 [DatabaseIdentifier:11843592] HPA:ENSG00000164975-SNAPC3 [DatabaseIdentifier:12128206] OpenTargets:ENSG00000164975 [DatabaseIdentifier:12142162] PDB:8ITY [DatabaseIdentifier:12142170] PDB:9FSS [DatabaseIdentifier:12142180] PDB:9K3U [DatabaseIdentifier:12142168] PDB:9FSO [DatabaseIdentifier:12142169] PDB:9FSR [DatabaseIdentifier:12203894] PDB:7XUR [DatabaseIdentifier:12142165] PDB:9FSP [DatabaseIdentifier:12140143] PDB:7ZWD [DatabaseIdentifier:12140150] PDB:7ZWC [DatabaseIdentifier:12140159] PDB:7ZXE [DatabaseIdentifier:12142178] PDB:9K3V [DatabaseIdentifier:12142166] PDB:9FSQ [DatabaseIdentifier:12142183] PDB:9LXN [DatabaseIdentifier:12142186] PDB:9K3B [DatabaseIdentifier:12142188] PDB:8IUH [DatabaseIdentifier:12140161] PDB:7ZX7 [DatabaseIdentifier:12140163] PDB:7ZX8 [DatabaseIdentifier:12142187] PDB:8IUE [DatabaseIdentifier:12269916] PRO:Q92966 [DatabaseIdentifier:12288430] Pharos - Targets:Q92966 [DatabaseIdentifier:12467380] RefSeq:XP_016870545.1 [DatabaseIdentifier:12467381] RefSeq:XP_054219597.1
databaseName	UniProt
dbId	64730
description	recommendedName: snRNA-activating protein complex subunit 3 shortName: SNAPc subunit 3 alternativeName: Proximal sequence element-binding transcription factor subunit beta shortName: PSE-binding factor subunit beta shortName: PTF subunit beta alternativeName: Small nuclear RNA-activating complex polypeptide 3 alternativeName: snRNA-activating protein complex 50 kDa subunit shortName: SNAPc 50 kDa subunit
displayName	UniProt:Q92966 SNAPC3
geneName	SNAPC3 SNAP50
identifier	Q92966
isSequenceChanged	false
keyword	3D-structure DNA-binding Nucleus Proteomics identification Reference proteome Transcription Transcription regulation
modified	[InstanceEdit:9926675] Weiser, Joel, 2024-11-03
moleculeType	Protein
name	SNAPC3
otherIdentifier	11739238_at 11739239_a_at 11739240_x_at 11753481_a_at 11763189_at 17083647 204001_PM_at 204001_at 210465_3p_s_at 210465_PM_s_at 210465_s_at 222286_PM_at 222286_at 229712_PM_at 229712_at 3163137 3163138 3163139 3163140 3163141 3163144 3163145 3163146 3163147 3163148 3163150 3163151 3163153 3163155 3163156 3163157 3163158 3163159 3163160 3163161 3163162 3163163 3163168 3163169 3163170 3163171 38224_at 43446_at 44248_at 64182_at 6619 8154394 90650_at A_14_P202180 A_33_P3389478 GE59334 GE84685 GE85118 GO:0000978 GO:0000995 GO:0001006 GO:0001046 GO:0003677 GO:0003681 GO:0005515 GO:0005634 GO:0005654 GO:0005730 GO:0006351 GO:0006366 GO:0006383 GO:0009301 GO:0016073 GO:0016604 GO:0019185 GO:0042795 GO:0042796 GO:0140223 HMNXSV003030192 HMNXSV003050458 HMNXSV003057337 Hs.22574.0.A1_3p_at Hs.22574.0.A1_3p_x_at Hs.82110.2.A1_3p_at ILMN_1803611 ILMN_2224300 PH_hs_0024310 TC09000075.hg U71300_at g1619945_3p_a_at g1619945_3p_s_at g1619945_3p_x_at g4507104_3p_at
physicalEntity	[EntityWithAccessionedSequence:R-HSA-83727] SNAPC3 [nucleoplasm] - Homo sapiens
referenceDatabase	[ReferenceDatabase:2] UniProt
referenceGene	[ReferenceDNASequence:ensembl:ENSG00000164975] ENSEMBL:ENSG00000164975 SNAPC3 [ReferenceDNASequence:12767180] UCSC:Q92966 SNAPC3 [ReferenceDNASequence:11383281] BioGPS Gene:6619 SNAPC3 [ReferenceDNASequence:11403656] COSMIC - genes:SNAPC3 SNAPC3 [ReferenceDNASequence:11418048] CTD Gene:6619 SNAPC3 [ReferenceDNASequence:11441282] dbSNP Gene:6619 SNAPC3 [ReferenceDNASequence:11822249] HGNC:11136 SNAPC3 [ReferenceDNASequence:11919991] KEGG:hsa:6619 SNAPC3 [ReferenceDNASequence:12013070] Monarch:6619 SNAPC3 [ReferenceDNASequence:12097163] NCBI Gene:6619 SNAPC3 [ReferenceDNASequence:12112996] OMIM:602348 SNAPC3
referenceTranscript	[ReferenceRNASequence:12648854] RefSeq:XM_017015056.3 SNAPC3 [ReferenceRNASequence:12648855] RefSeq:NM_001039697.2 SNAPC3 [ReferenceRNASequence:12648856] RefSeq:XM_054363622.1 SNAPC3
schemaClass	ReferenceGeneProduct
secondaryIdentifier	SNPC3_HUMAN D3DRI8 Q2VPI6 Q5T285
sequenceLength	411
species	[Species:48887] Homo sapiens
stId	uniprot:Q92966
url	http://purl.uniprot.org/uniprot/Q92966

(referenceEntity)	[EntityWithAccessionedSequence:R-HSA-83727] SNAPC3 [nucleoplasm]
(interactor)	[UndirectedInteraction:11182739] UniProt:P04792 <-> UniProt:Q92966 (IntAct) [UndirectedInteraction:11239023] UniProt:O76024 <-> UniProt:Q92966 (IntAct)

UniProt:Q92966 SNAPC3 Show undefined attributes

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