Reactome | UniProt:Q92733 PRCC

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UniProt:Q92733 PRCC Show undefined attributes

chain	chain:1-491
checksum	F99CFD9D42725D57
comment	FUNCTION May regulate cell cycle progression through interaction with MAD2L2.SUBUNIT Interacts with MAD2L2; the interaction is direct.INTERACTION Ubiquitous in fetal and adult tissues.DISEASE A chromosomal aberration involving PRCC is found in patients with papillary renal cell carcinoma. Translocation t(X;1)(p11.2;q21.2) with TFE3.
crossReference	[DatabaseIdentifier:12470197] RefSeq:NP_005964.3 [DatabaseIdentifier:12289364] Pharos - Targets:Q92733 [DatabaseIdentifier:12271262] PRO:Q92733 [DatabaseIdentifier:12137335] Orphanet:PRCC [DatabaseIdentifier:12129151] OpenTargets:ENSG00000143294 [DatabaseIdentifier:11844523] HPA:ENSG00000143294-PRCC [DatabaseIdentifier:11807540] GlyGen:Q92733 [DatabaseIdentifier:11791522] GeneCards:PRCC [DatabaseIdentifier:11762082] ENSEMBL:ENST00000271526 [DatabaseIdentifier:11639383] ENSEMBL:ENSP00000271526 [DatabaseIdentifier:11520477] ENSEMBL:ENSG00000143294
databaseName	UniProt
dbId	62106
description	recommendedName: Proline-rich protein PRCC alternativeName: Papillary renal cell carcinoma translocation-associated gene protein
displayName	UniProt:Q92733 PRCC
geneName	PRCC TPRC
identifier	Q92733
isSequenceChanged	false
keyword	Cell cycle Chromosomal rearrangement Nucleus Phosphoprotein Proteomics identification Proto-oncogene Reference proteome
modified	[InstanceEdit:9926675] Weiser, Joel, 2024-11-03
moleculeType	Protein
name	PRCC
otherIdentifier	11716336_a_at 16672170 208938_PM_at 208938_at 2361732 2361735 2361736 2361737 2361738 2361739 2361740 2361741 2361744 2361745 2361746 2361747 2361748 2361749 2361750 2361751 2361752 2361754 2361755 2361756 2361758 39149_at 5546 7906235 A_14_P134118 A_23_P23411 GE60221 GO:0005515 GO:0005634 GO:0005654 GO:0016607 GO:0051726 HMNXSV003021590 ILMN_1802843 ILMN_1809818 PH_hs_0000993 TC01001327.hg X99720_rna1_at g13436211_3p_x_at
physicalEntity	[EntityWithAccessionedSequence:R-HSA-8867896] PRCC [nucleoplasm] - Homo sapiens
referenceDatabase	[ReferenceDatabase:2] UniProt
referenceGene	[ReferenceDNASequence:12767911] UCSC:Q92733 PRCC [ReferenceDNASequence:12113838] OMIM:179755 PRCC [ReferenceDNASequence:12098276] NCBI Gene:5546 PRCC [ReferenceDNASequence:12014183] Monarch:5546 PRCC [ReferenceDNASequence:11921011] KEGG:hsa:5546 PRCC [ReferenceDNASequence:11823193] HGNC:9343 PRCC [ReferenceDNASequence:11441396] dbSNP Gene:5546 PRCC [ReferenceDNASequence:11419297] CTD Gene:5546 PRCC [ReferenceDNASequence:11403760] COSMIC - genes:PRCC PRCC [ReferenceDNASequence:11384394] BioGPS Gene:5546 PRCC [ReferenceDNASequence:ensembl:ENSG00000143294] ENSEMBL:ENSG00000143294 PRCC
referenceTranscript	[ReferenceRNASequence:12651666] RefSeq:NM_005973.4 PRCC
schemaClass	ReferenceGeneProduct
secondaryIdentifier	PRCC_HUMAN A8K1F7 O00665 O00724 Q5SZ06
sequenceLength	491
species	[Species:48887] Homo sapiens
stId	uniprot:Q92733
url	http://purl.uniprot.org/uniprot/Q92733

Referrals

(interactor)	[UndirectedInteraction:11295723] UniProt:P38646 <-> UniProt:Q92733 (IntAct) [UndirectedInteraction:11234303] UniProt:P00533 <-> UniProt:Q92733 (IntAct)
(referenceEntity)	[EntityWithAccessionedSequence:R-HSA-8867896] PRCC [nucleoplasm]

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