Reactome | UniProt:Q8TDB8 SLC2A14

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UniProt:Q8TDB8 SLC2A14 Show undefined attributes

chain	chain:1-520
checksum	EA304A5189087690
comment	FUNCTION Hexose transporter that can mediate the transport of glucose and dehydroascorbate across the cell membrane.CATALYTIC ACTIVITY D-glucose(out) = D-glucose(in)CATALYTIC ACTIVITY L-dehydroascorbate(out) = L-dehydroascorbate(in)SUBCELLULAR LOCATION Mainly expressed in testis (PubMed:12504846, PubMed:27460888). Also expressed in small intestine, liver and kidney (PubMed:27460888).MISCELLANEOUS GLUT14 is a recent (less than 5 M year old) duplication of GLUT3.SIMILARITY Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
created	[InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53
crossReference	[DatabaseIdentifier:11459904] ENSEMBL:ENSG00000173262 [DatabaseIdentifier:11552503] ENSEMBL:ENSP00000482927 [DatabaseIdentifier:11552500] ENSEMBL:ENSP00000445929 [DatabaseIdentifier:11552498] ENSEMBL:ENSP00000379834 [DatabaseIdentifier:11552505] ENSEMBL:ENSP00000407287 [DatabaseIdentifier:11552504] ENSEMBL:ENSP00000438484 [DatabaseIdentifier:11552502] ENSEMBL:ENSP00000443903 [DatabaseIdentifier:11552501] ENSEMBL:ENSP00000340450 [DatabaseIdentifier:11552497] ENSEMBL:ENSP00000440480 [DatabaseIdentifier:11552499] ENSEMBL:ENSP00000440492 [DatabaseIdentifier:11675200] ENSEMBL:ENST00000543909 [DatabaseIdentifier:11675197] ENSEMBL:ENST00000396589 [DatabaseIdentifier:11675202] ENSEMBL:ENST00000542505 [DatabaseIdentifier:11675196] ENSEMBL:ENST00000616981 [DatabaseIdentifier:11675204] ENSEMBL:ENST00000431042 [DatabaseIdentifier:11675198] ENSEMBL:ENST00000539924 [DatabaseIdentifier:11675203] ENSEMBL:ENST00000535295 [DatabaseIdentifier:11675199] ENSEMBL:ENST00000340749 [DatabaseIdentifier:11675201] ENSEMBL:ENST00000542546 [DatabaseIdentifier:11779919] Guide to Pharmacology - Targets:879 [DatabaseIdentifier:11793574] GeneCards:SLC2A14 [DatabaseIdentifier:11809528] GlyGen:Q8TDB8 [DatabaseIdentifier:11830339] HMDB Protein:HMDBP11763 [DatabaseIdentifier:11846563] HPA:ENSG00000173262-SLC2A14 [DatabaseIdentifier:12131223] OpenTargets:ENSG00000173262 [DatabaseIdentifier:12253395] PRO:Q8TDB8 [DatabaseIdentifier:12291417] Pharos - Targets:Q8TDB8 [DatabaseIdentifier:12340017] RefSeq:NP_001273166.1 [DatabaseIdentifier:12340015] RefSeq:NP_001273163.1 [DatabaseIdentifier:12340016] RefSeq:NP_703150.1 [DatabaseIdentifier:12340018] RefSeq:NP_001273164.1 [DatabaseIdentifier:12340019] RefSeq:NP_001273165.1 [DatabaseIdentifier:12340014] RefSeq:NP_001273162.1
databaseName	UniProt
dbId	231363
description	recommendedName: fullName evidence="13"Solute carrier family 2, facilitated glucose transporter member 14 alternativeName: fullName evidence="7"Glucose transporter type 14 shortName evidence="7"GLUT-14
displayName	UniProt:Q8TDB8 SLC2A14
geneName	SLC2A14 GLUT14
identifier	Q8TDB8
isSequenceChanged	false
keyword	Alternative splicing Cell membrane Developmental protein Differentiation Glycoprotein Membrane Proteomics identification Reference proteome Spermatogenesis Sugar transport Transmembrane Transmembrane helix Transport
modified	[InstanceEdit:9963647] Weiser, Joel, 2025-08-15
moleculeType	Protein
name	SLC2A14
otherIdentifier	11734657_s_at 11736555_s_at 11736556_s_at 11747751_s_at 11752739_s_at 11759204_a_at 144195 16760842 216236_PM_s_at 216236_s_at 222088_PM_s_at 222088_s_at 2416636 3105895 3442813 3442814 3442815 3442816 3442817 3442818 3442819 3442820 3442821 3442822 3442823 3442824 3442825 3442826 3442827 3442828 3442830 3442831 3442832 3442833 3442834 3442835 3442836 3442837 3442838 3442855 3442869 3442870 3442872 3442877 3442880 3442882 3442883 3442884 3442922 52658_at 56198_at 7960850 A_32_P47754 GE57861 GO:0005536 GO:0005634 GO:0005886 GO:0007283 GO:0015149 GO:0016020 GO:0016235 GO:0022414 GO:0022857 GO:0030154 GO:0033300 GO:0042995 GO:0043204 GO:0046323 GO:0055056 GO:0055085 GO:0070837 GO:1904659 HMNXSV003010684 Hs.7594.1.A1_3p_a_at Hs.7594.2.A1_3p_a_at ILMN_1668865 PH_hs_0041114 TC12001168.hg TC12002734.hg
physicalEntity	[EntityWithAccessionedSequence:R-HSA-5216128] SLC2A14 [plasma membrane] - Homo sapiens
referenceDatabase	[ReferenceDatabase:2] UniProt
referenceGene	[ReferenceDNASequence:ensembl:ENSG00000173262] ENSEMBL:ENSG00000173262 SLC2A14 [ReferenceDNASequence:12678203] UCSC:Q8TDB8 SLC2A14 [ReferenceDNASequence:11324591] BioGPS Gene:144195 SLC2A14 [ReferenceDNASequence:11391837] COSMIC - genes:SLC2A14 SLC2A14 [ReferenceDNASequence:11422072] CTD Gene:144195 SLC2A14 [ReferenceDNASequence:11427543] dbSNP Gene:144195 SLC2A14 [ReferenceDNASequence:11825267] HGNC:18301 SLC2A14 [ReferenceDNASequence:11867073] KEGG:hsa:144195 SLC2A14 [ReferenceDNASequence:11954380] Monarch:144195 SLC2A14 [ReferenceDNASequence:12038473] NCBI Gene:144195 SLC2A14 [ReferenceDNASequence:12115702] OMIM:611039 SLC2A14
referenceTranscript	[ReferenceRNASequence:12521914] RefSeq:NM_001286237.2 SLC2A14 [ReferenceRNASequence:12521913] RefSeq:NM_001286236.2 SLC2A14 [ReferenceRNASequence:12521917] RefSeq:NM_001286233.2 SLC2A14 [ReferenceRNASequence:12521918] RefSeq:NM_153449.4 SLC2A14 [ReferenceRNASequence:12521916] RefSeq:NM_001286235.2 SLC2A14 [ReferenceRNASequence:12521915] RefSeq:NM_001286234.2 SLC2A14
schemaClass	ReferenceGeneProduct
secondaryIdentifier	GTR14_HUMAN B3KVB5 B3KWW7 B7Z844 B7ZAC3 Q6UY84 Q8TDB9
sequenceLength	520
species	[Species:48887] Homo sapiens
stId	uniprot:Q8TDB8
url	http://purl.uniprot.org/uniprot/Q8TDB8

Referrals

(referenceEntity)	[EntityWithAccessionedSequence:R-HSA-5216128] SLC2A14 [plasma membrane]
(interactor)	[UndirectedInteraction:11173365] UniProt:P11169 <-> UniProt:Q8TDB8 (IntAct)

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