UniProt:Q8TC07 TBC1D15

chain
  • initiator methionine:1
  • chain:2-691
checksum D880DBE4D5758EC7
comment
  • FUNCTION Acts as a GTPase activating protein for RAB7A. Does not act on RAB4, RAB5 or RAB6 (By similarity).SUBUNIT Interacts with non-phosphorylated form of RAB8A; phosphorylation of RAB8A at 'Thr-72' disrupts this interaction (PubMed:26824392). Interacts with ARMC12 (PubMed:33536340).INTERACTION Ubiquitous.
created [InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53
crossReference
databaseName UniProt
dbId 250629
description
  • recommendedName: TBC1 domain family member 15 alternativeName: GTPase-activating protein RAB7 shortName: GAP for RAB7 shortName: Rab7-GAP
displayName UniProt:Q8TC07 TBC1D15
geneName
  • TBC1D15
identifier Q8TC07
isSequenceChanged false
keyword
  • Acetylation
  • Alternative splicing
  • Cytoplasm
  • GTPase activation
  • Phosphoprotein
  • Proteomics identification
  • Reference proteome
modified [InstanceEdit:9963647] Weiser, Joel, 2025-08-15
moleculeType Protein
name
  • TBC1D15
otherIdentifier
  • 11727377_a_at
  • 11727378_at
  • 11757471_s_at
  • 16754208
  • 218268_PM_at
  • 218268_at
  • 230072_PM_at
  • 230072_at
  • 3422327
  • 3422328
  • 3422330
  • 3422333
  • 3422334
  • 3422336
  • 3422338
  • 3422339
  • 3422340
  • 3422341
  • 3422344
  • 3422345
  • 3422346
  • 3422347
  • 3422348
  • 3422349
  • 3422350
  • 3422351
  • 3422354
  • 3422355
  • 3422356
  • 3422357
  • 3422359
  • 3422360
  • 3422361
  • 3422363
  • 3422364
  • 3422367
  • 3422368
  • 3422370
  • 3422371
  • 3422373
  • 3422374
  • 3422375
  • 3422383
  • 3422384
  • 3422385
  • 46955_at
  • 64420_at
  • 64786
  • 70482_at
  • 76716_at
  • 7957186
  • 82931_at
  • A_14_P137092
  • A_23_P139558
  • GE56826
  • GO:0005096
  • GO:0005515
  • GO:0005576
  • GO:0005737
  • GO:0043087
  • GO:0098772
  • HMNXSV003022168
  • Hs.146220.0.A1_3p_at
  • ILMN_1803941
  • PH_hs_0039971
  • TC12000628.hg
  • TC12002446.hg
  • g12232450_3p_at
physicalEntity
referenceDatabase [ReferenceDatabase:2] UniProt
referenceGene
referenceTranscript
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • TBC15_HUMAN
  • B4DMT9
  • B9A6L6
  • J3KNI9
  • Q9HA83
sequenceLength 691
species [Species:48887] Homo sapiens
stId uniprot:Q8TC07
url http://purl.uniprot.org/uniprot/Q8TC07

Referrals

(referenceEntity)
(interactor)
Cite Us!