UniProt:Q8TAT2 FGFBP3

chain
  • signal peptide:1-26
  • chain:27-258
checksum C6290744F0AB9DEF
comment
  • FUNCTION Heparin-binding protein which binds to FGF2, prevents binding of FGF2 to heparin and probably inhibits immobilization of FGF2 on extracellular matrix glycosaminoglycans, allowing its release and subsequent activation of FGFR signaling which leads to increased vascular permeability.SUBUNIT Interacts with FGF2.SUBCELLULAR LOCATION Belongs to the fibroblast growth factor-binding protein family.
created [InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53
crossReference
databaseName UniProt
dbId 229571
description
  • recommendedName: Fibroblast growth factor-binding protein 3 shortName: FGF-BP3 shortName: FGF-binding protein 3 shortName: FGFBP-3
displayName UniProt:Q8TAT2 FGFBP3
geneName
  • FGFBP3
  • C10orf13
  • PSEC0101
identifier Q8TAT2
isSequenceChanged false
keyword
  • Disulfide bond
  • Growth factor binding
  • Heparin-binding
  • Proteomics identification
  • Reference proteome
  • Secreted
  • Signal
modified [InstanceEdit:9926675] Weiser, Joel, 2024-11-03
moleculeType Protein
name
  • FGFBP3
otherIdentifier
  • 11736294_at
  • 11736295_at
  • 143282
  • 16716520
  • 238453_PM_at
  • 238453_at
  • 3300212
  • 3300213
  • 3300214
  • 3300215
  • 3300216
  • 3300217
  • 3300218
  • 3300219
  • 7935006
  • 81750_at
  • A_23_P417994
  • A_24_P201381
  • GE548566
  • GO:0003013
  • GO:0005576
  • GO:0007267
  • GO:0008201
  • GO:0017134
  • GO:0019838
  • GO:0030312
  • GO:0031012
  • GO:0043117
  • GO:0045743
  • HMNXSV003023493
  • Hs.159450.0.A1_3p_at
  • ILMN_1686961
  • PH_hs_0002960
  • TC10001525.hg
physicalEntity
referenceDatabase [ReferenceDatabase:2] UniProt
referenceGene
referenceTranscript
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • FGFP3_HUMAN
  • B2RD68
  • Q8NBN0
sequenceLength 258
species [Species:48887] Homo sapiens
stId uniprot:Q8TAT2
url http://purl.uniprot.org/uniprot/Q8TAT2
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