UniProt:Q8TAG9 EXOC6

chain
  • chain:1-804
checksum 413251A5BA6543C4
comment
  • FUNCTION Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Together with RAB11A, RAB3IP, RAB8A, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis (By similarity).SUBUNIT The exocyst complex is composed of EXOC1, EXOC2, EXOC3, EXOC4, EXOC5, EXOC6, EXOC7 and EXOC8 (By similarity). Interacts with CNTRL. Interacts with RAB11A in a GTP-dependent manner (By similarity).INTERACTION Perinuclear in undifferentiated cells. Redistributes to growing neurites and growth cones during neuronal differentiation. Colocalizes with CNTRL/centriolin at the midbody ring (PubMed:16213214).ALTERNATIVE PRODUCTS Belongs to the SEC15 family.SEQUENCE CAUTION Extended N-terminus.
crossReference
databaseName UniProt
dbId 63974
description
  • recommendedName: Exocyst complex component 6 alternativeName: Exocyst complex component Sec15A alternativeName: SEC15-like protein 1
displayName UniProt:Q8TAG9 EXOC6
geneName
  • EXOC6
  • SEC15A
  • SEC15L
  • SEC15L1
identifier Q8TAG9
isSequenceChanged false
keyword
  • Alternative splicing
  • Cell projection
  • Cytoplasm
  • Exocytosis
  • Protein transport
  • Proteomics identification
  • Reference proteome
  • Transport
modified [InstanceEdit:9926675] Weiser, Joel, 2024-11-03
moleculeType Protein
name
  • EXOC6
otherIdentifier
  • 11723221_a_at
  • 11755493_a_at
  • 16707503
  • 226259_PM_at
  • 226259_at
  • 232599_PM_at
  • 232599_at
  • 233924_PM_s_at
  • 233924_s_at
  • 3258257
  • 3258261
  • 3258262
  • 3258270
  • 3258271
  • 3258283
  • 3258284
  • 3258285
  • 3258286
  • 3258288
  • 3258289
  • 3258290
  • 3258292
  • 3258293
  • 3258295
  • 3258298
  • 3258301
  • 3258302
  • 3258303
  • 3258304
  • 3258306
  • 3258307
  • 3258308
  • 3258309
  • 3258311
  • 3258317
  • 3258318
  • 3258319
  • 3258320
  • 3258323
  • 3258328
  • 3258329
  • 3258338
  • 3258341
  • 3258342
  • 3258355
  • 3258356
  • 49287_at
  • 54536
  • 59310_at
  • 7929288
  • A_14_P139287
  • A_23_P169576
  • A_32_P58280
  • GE56714
  • GE650089
  • GO:0000145
  • GO:0000281
  • GO:0000910
  • GO:0005515
  • GO:0005737
  • GO:0005829
  • GO:0005886
  • GO:0006886
  • GO:0006887
  • GO:0006893
  • GO:0006904
  • GO:0015031
  • GO:0016192
  • GO:0030426
  • GO:0042995
  • GO:0048471
  • GO:0061024
  • GO:0090148
  • GO:0090522
  • GO:0090543
  • HMNXSV003000060
  • HMNXSV003056933
  • Hs.110454.0.S1_3p_at
  • Hs.110454.1.S1_3p_a_at
  • Hs.272374.0.S1_3p_at
  • ILMN_1651628
  • ILMN_1667686
  • ILMN_1679687
  • PH_hs_0023364
  • TC10000661.hg
physicalEntity
referenceDatabase [ReferenceDatabase:2] UniProt
referenceGene
referenceTranscript
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • EXOC6_HUMAN
  • E9PHI3
  • Q5VXH8
  • Q9NZ24
sequenceLength 804
species [Species:48887] Homo sapiens
stId uniprot:Q8TAG9
url http://purl.uniprot.org/uniprot/Q8TAG9

Referrals

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