UniProt:Q8IYJ3 SYTL1

chain
  • chain:1-562
checksum 056BE1F16723EE19
comment
  • FUNCTION May play a role in vesicle trafficking (By similarity). Binds phosphatidylinositol 3,4,5-trisphosphate. Acts as a RAB27A effector protein and may play a role in cytotoxic granule exocytosis in lymphocytes (By similarity).SUBUNIT Monomer. Binds NRXN1. Binds RAB27A that has been activated by GTP-binding via its N-terminus (By similarity). Binds NCF2.INTERACTION Peripheral membrane protein tightly bound to the cytoplasmic side of cellular membranes.ALTERNATIVE PRODUCTS Highly expressed in bone marrow and lymphoid tissues. Detected at lower levels in cerebellum, occipital lobe, prostate, stomach, kidney, appendix, lung and trachea. Expressed in cytotoxic T-lymphocytes (CTL).
crossReference
databaseName UniProt
dbId 102451
description
  • recommendedName: Synaptotagmin-like protein 1 alternativeName: Exophilin-7 alternativeName: Protein JFC1
displayName UniProt:Q8IYJ3 SYTL1
geneName
  • SYTL1
  • SLP1
  • SB146
identifier Q8IYJ3
isSequenceChanged false
keyword
  • Alternative splicing
  • Cell membrane
  • Exocytosis
  • Membrane
  • Phosphoprotein
  • Proteomics identification
  • Reference proteome
  • Repeat
modified [InstanceEdit:9926675] Weiser, Joel, 2024-11-03
moleculeType Protein
name
  • SYTL1
otherIdentifier
  • 11754370_x_at
  • 11754637_a_at
  • 16661398
  • 227134_PM_at
  • 227134_at
  • 2326994
  • 2326995
  • 2326996
  • 2326997
  • 2326998
  • 2326999
  • 2327000
  • 2327001
  • 2327002
  • 2327003
  • 2327004
  • 2327005
  • 2327006
  • 2327007
  • 2327008
  • 2327010
  • 2327011
  • 2327012
  • 2327013
  • 2327014
  • 2327015
  • 2327016
  • 2327017
  • 2327018
  • 2327019
  • 2327020
  • 2327021
  • 2327022
  • 2327023
  • 2327024
  • 2327025
  • 2327026
  • 2327027
  • 2327028
  • 2327029
  • 2327030
  • 2327031
  • 2327033
  • 2327034
  • 44820_f_at
  • 7899323
  • 84958
  • 91211_at
  • A_23_P46390
  • A_32_P217773
  • A_33_P3235321
  • A_33_P3235322
  • A_33_P3266744
  • GE83565
  • GO:0005515
  • GO:0005886
  • GO:0006886
  • GO:0006887
  • GO:0012505
  • GO:0016020
  • GO:0016192
  • GO:0031267
  • GO:0031410
  • GO:0031528
  • GO:0042043
  • GO:0042470
  • GO:0070062
  • GO:0070382
  • HMNXSV003003801
  • HMNXSV003007833
  • Hs.25895.0.A1_3p_at
  • ILMN_1750785
  • PH_hs_0002278
  • TC01000361.hg
physicalEntity
referenceDatabase [ReferenceDatabase:2] UniProt
referenceGene
referenceTranscript
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • SYTL1_HUMAN
  • Q5SSC9
  • Q96BB6
  • Q96GU6
  • Q96S89
  • Q96SI0
sequenceLength 562
species [Species:48887] Homo sapiens
stId uniprot:Q8IYJ3
url http://purl.uniprot.org/uniprot/Q8IYJ3
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