Reactome | UniProt:Q86XI2 NCAPG2

Schema > ReferenceGeneProduct > Entries

UniProt:Q86XI2 NCAPG2 Show undefined attributes

chain	chain:1-1143
checksum	7C7B7FA2A7F0683C
comment	FUNCTION Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis.SUBUNIT Component of the condensin-2 complex, which contains the SMC2 and SMC4 heterodimer, and 3 non SMC subunits that probably regulate the complex: NCAPH2, NCAPD3 and NCAPG2.INTERACTION The disease is caused by variants affecting the gene represented in this entry.
created	[InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53
crossReference	[DatabaseIdentifier:12395505] RefSeq:NP_060230.5 [DatabaseIdentifier:12395503] RefSeq:XP_047276495.1 [DatabaseIdentifier:12395501] RefSeq:XP_054214494.1 [DatabaseIdentifier:12395508] RefSeq:NP_001268862.1 [DatabaseIdentifier:12395504] RefSeq:XP_047276494.1 [DatabaseIdentifier:12395500] RefSeq:XP_054214495.1 [DatabaseIdentifier:12395502] RefSeq:XP_054214493.1 [DatabaseIdentifier:12395507] RefSeq:XP_011514659.1 [DatabaseIdentifier:12395506] RefSeq:NP_001268861.1 [DatabaseIdentifier:12279330] Pharos - Targets:Q86XI2 [DatabaseIdentifier:12235765] PRO:Q86XI2 [DatabaseIdentifier:12139194] PDB:9F5W [DatabaseIdentifier:12118986] OpenTargets:ENSG00000146918 [DatabaseIdentifier:11834543] HPA:ENSG00000146918-NCAPG2 [DatabaseIdentifier:11797179] GlyGen:Q86XI2 [DatabaseIdentifier:11781412] GeneCards:NCAPG2 [DatabaseIdentifier:11710398] ENSEMBL:ENST00000409339 [DatabaseIdentifier:11710400] ENSEMBL:ENST00000409423 [DatabaseIdentifier:11710399] ENSEMBL:ENST00000356309 [DatabaseIdentifier:11587700] ENSEMBL:ENSP00000348657 [DatabaseIdentifier:11587699] ENSEMBL:ENSP00000387007 [DatabaseIdentifier:11587701] ENSEMBL:ENSP00000386569 [DatabaseIdentifier:11484862] ENSEMBL:ENSG00000146918
databaseName	UniProt
dbId	224602
description	recommendedName: Condensin-2 complex subunit G2 alternativeName: Chromosome-associated protein G2 shortName: CAP-G2 shortName: hCAP-G2 alternativeName: Leucine zipper protein 5 alternativeName: Non-SMC condensin II complex subunit G2
displayName	UniProt:Q86XI2 NCAPG2
geneName	NCAPG2 LUZP5
identifier	Q86XI2
isSequenceChanged	false
keyword	3D-structure Alternative splicing Cell cycle Cell division Disease variant DNA condensation Mitosis Nucleus Phosphoprotein Proteomics identification Reference proteome
modified	[InstanceEdit:9983091] Weiser, Joel, 2026-02-20
moleculeType	Protein
name	NCAPG2
otherIdentifier	11728071_a_at 11756784_x_at 11760138_at 11761327_a_at 11761328_x_at 17064939 219588_PM_s_at 219588_s_at 3082188 3082189 3082190 3082193 3082194 3082195 3082196 3082197 3082198 3082201 3082202 3082203 3082204 3082205 3082206 3082207 3082208 3082209 3082210 3082212 3082213 3082214 3082215 3082216 3082217 3082218 3082220 3082221 3082222 3082224 3082225 3082226 3082227 3082228 3082229 3082230 3082231 3082232 3082233 3082234 3082235 3082236 3082237 3082238 3082239 3728531 54892 55928_at 8144153 A_23_P168747 A_33_P3659876 GE87651 GO:0000070 GO:0000228 GO:0000794 GO:0000796 GO:0001833 GO:0005515 GO:0005634 GO:0005654 GO:0005694 GO:0006325 GO:0006351 GO:0006366 GO:0016020 GO:0016607 GO:0030154 GO:0030218 GO:0030261 GO:0031981 GO:0043425 GO:0051301 GO:0051984 GO:0140117 GO:1905820 GO:1905821 HMNXSV003006061 HMNXSV003007632 ILMN_1669826 ILMN_2066756 PH_hs_0040683 TC07002083.hg g8923292_3p_a_at
physicalEntity	[EntityWithAccessionedSequence:R-HSA-2294572] p-S-NCAPG2 [nucleoplasm] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-1629799] NCAPG2 [nucleoplasm] - Homo sapiens
referenceDatabase	[ReferenceDatabase:2] UniProt
referenceGene	[ReferenceDNASequence:12744762] UCSC:Q86XI2 NCAPG2 [ReferenceDNASequence:12104931] OMIM:608532 NCAPG2 [ReferenceDNASequence:12064032] NCBI Gene:54892 NCAPG2 [ReferenceDNASequence:11979939] Monarch:54892 NCAPG2 [ReferenceDNASequence:11889974] KEGG:hsa:54892 NCAPG2 [ReferenceDNASequence:11813014] HGNC:21904 NCAPG2 [ReferenceDNASequence:11437616] dbSNP Gene:54892 NCAPG2 [ReferenceDNASequence:11404497] CTD Gene:54892 NCAPG2 [ReferenceDNASequence:11400461] COSMIC - genes:NCAPG2 NCAPG2 [ReferenceDNASequence:11350150] BioGPS Gene:54892 NCAPG2 [ReferenceDNASequence:ensembl:ENSG00000146918] ENSEMBL:ENSG00000146918 NCAPG2
referenceTranscript	[ReferenceRNASequence:12577269] RefSeq:NM_001281933.2 NCAPG2 [ReferenceRNASequence:12577265] RefSeq:XM_047420539.1 NCAPG2 [ReferenceRNASequence:12577271] RefSeq:NM_017760.6 NCAPG2 [ReferenceRNASequence:12577272] RefSeq:XM_011516357.3 NCAPG2 [ReferenceRNASequence:12577266] RefSeq:XM_047420538.1 NCAPG2 [ReferenceRNASequence:12577270] RefSeq:NM_001281932.2 NCAPG2 [ReferenceRNASequence:12577267] RefSeq:XM_054358518.1 NCAPG2 [ReferenceRNASequence:12577268] RefSeq:XM_054358519.1 NCAPG2 [ReferenceRNASequence:12577264] RefSeq:XM_054358520.1 NCAPG2
schemaClass	ReferenceGeneProduct
secondaryIdentifier	CNDG2_HUMAN A4D228 Q7Z3J9 Q8WUG8 Q9BRX6 Q9H8S2 Q9H9K6
sequenceLength	1143
species	[Species:48887] Homo sapiens
stId	uniprot:Q86XI2
url	http://purl.uniprot.org/uniprot/Q86XI2

Referrals

(referenceEntity)	[EntityWithAccessionedSequence:R-HSA-2294572] p-S-NCAPG2 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-1629799] NCAPG2 [nucleoplasm]
(referenceSequence)	[ModifiedResidue:2294583] O-phospho-L-serine at unknown position

Cite Us!