FUNCTION Core histones chaperone involved in chromatin reprogramming, specially during fertilization and early embryonic development. Probably involved in sperm DNA decondensation during fertilization.SUBUNIT Homopentamer, when bound to H2A-H2B dimers only. Homodecamer of two stacked pentamers, when bound to H2A-H2B dimers and H3-H4 tetramers simultaneously.INTERACTION Found in the oocyte nucleus before nuclear membrane breakdown, after which it is redistributed to the cytoplasm.ALTERNATIVE PRODUCTS The acidic tract A2 mediates histone binding.SIMILARITY Belongs to the nucleoplasmin family.
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