Reactome | UniProt:Q7RTY9 PRSS41

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UniProt:Q7RTY9 PRSS41 Show undefined attributes

chain	signal peptide:1-19 propeptide:20-54 chain:55-299 propeptide:300-318
checksum	D792213630CF15C3
comment	SUBCELLULAR LOCATION Localized in the plasma membrane of spermatogonia. Localized in intracellular compartment in spermatocytes, probably in the Golgi apparatus (By similarity).PTM N-glycosylated.SIMILARITY Belongs to the peptidase S1 family.
created	[InstanceEdit:384350] Kanapin, AA, 2008-11-26 14:00:39
crossReference	[DatabaseIdentifier:12367193] RefSeq:NP_001341515.2 [DatabaseIdentifier:12285344] Pharos - Targets:Q7RTY9 [DatabaseIdentifier:12264398] PRO:Q7RTY9 [DatabaseIdentifier:12125036] OpenTargets:ENSG00000215148 [DatabaseIdentifier:11802873] GlyGen:Q7RTY9 [DatabaseIdentifier:11787425] GeneCards:PRSS41
databaseName	UniProt
dbId	386338
description	recommendedName: Serine protease 41 ecNumber: 3.4.21.- alternativeName: Testis serine protease 1 shortName: TESSP-1
displayName	UniProt:Q7RTY9 PRSS41
geneName	PRSS41 TESSP1
identifier	Q7RTY9
isSequenceChanged	false
keyword	Cell membrane Disulfide bond Glycoprotein GPI-anchor Hydrolase Lipoprotein Membrane Protease Proteomics identification Reference proteome Serine protease Signal
modified	[InstanceEdit:9917590] Weiser, Joel, 2024-08-09
moleculeType	Protein
name	PRSS41
physicalEntity	[EntityWithAccessionedSequence:R-HSA-8941085] cleaved GPI-PRSS41 [extracellular region] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-8940698] GPI-PRSS41 [plasma membrane] - Homo sapiens
referenceDatabase	[ReferenceDatabase:2] UniProt
referenceGene	[ReferenceDNASequence:12738057] UCSC:Q7RTY9 PRSS41 [ReferenceDNASequence:12050796] NCBI Gene:360226 PRSS41 [ReferenceDNASequence:11966703] Monarch:360226 PRSS41 [ReferenceDNASequence:11877960] KEGG:hsa:360226 PRSS41 [ReferenceDNASequence:11819065] HGNC:30715 PRSS41 [ReferenceDNASequence:11436285] dbSNP Gene:360226 PRSS41 [ReferenceDNASequence:11413130] CTD Gene:360226 PRSS41 [ReferenceDNASequence:11399299] COSMIC - genes:PRSS41 PRSS41 [ReferenceDNASequence:11336914] BioGPS Gene:360226 PRSS41 [ReferenceDNASequence:ensembl:ENSG00000215148] ENSEMBL:ENSG00000215148 PRSS41
referenceTranscript	[ReferenceRNASequence:12549034] RefSeq:NM_001354586.3 PRSS41
schemaClass	ReferenceGeneProduct
secondaryIdentifier	PRS41_HUMAN
sequenceLength	318
species	[Species:48887] Homo sapiens
stId	uniprot:Q7RTY9
url	http://purl.uniprot.org/uniprot/Q7RTY9

Referrals

(referenceEntity)	[EntityWithAccessionedSequence:R-HSA-8941085] cleaved GPI-PRSS41 [extracellular region] [EntityWithAccessionedSequence:R-HSA-8940698] GPI-PRSS41 [plasma membrane]
(referenceSequence)	[GroupModifiedResidue:8941041] L-serine amide (6-O-(2-aminoethylphosphono)-alpha-D-Man-(1->2)-alpha-D-Man-(1->6)-alpha-D-Man-(1->4)-alpha-D-GlcN-(1->6)-D-myo-inositol group) at 299 [GroupModifiedResidue:8940699] L-serine amide (GPI-anchor amidated amino acid carboxyl end residue(1?)) at 299

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