UniProt:Q6IPR3 TYW3

chain
  • chain:1-259
checksum 150BA9247232324D
comment
  • FUNCTION Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA (By similarity).CATALYTIC ACTIVITY 4-demethyl-7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine = 7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-homocysteine + H(+)PATHWAY tRNA modification; wybutosine-tRNA(Phe) biosynthesis.INTERACTION Belongs to the TYW3 family.
created [InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53
crossReference
databaseName UniProt
dbId 253249
description
  • recommendedName: tRNA wybutosine-synthesizing protein 3 homolog shortName: tRNA-yW-synthesizing protein 3 ecNumber: 2.1.1.282 alternativeName: tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase
displayName UniProt:Q6IPR3 TYW3
geneName
  • TYW3
  • C1orf171
identifier Q6IPR3
isSequenceChanged false
keyword
  • Alternative splicing
  • Methyltransferase
  • Phosphoprotein
  • Proteomics identification
  • Reference proteome
  • S-adenosyl-L-methionine
  • Transferase
  • tRNA processing
modified [InstanceEdit:9939033] Weiser, Joel, 2025-02-21
moleculeType Protein
name
  • TYW3
otherIdentifier
  • 11739265_at
  • 11751727_s_at
  • 127253
  • 16666204
  • 227141_PM_at
  • 227141_at
  • 2342392
  • 2342393
  • 2342395
  • 2342396
  • 2342397
  • 2342399
  • 2342400
  • 2342401
  • 2342402
  • 2342405
  • 2342406
  • 2342407
  • 2342408
  • 2342409
  • 2342411
  • 2342412
  • 2342413
  • 2342414
  • 2342415
  • 2342416
  • 2342417
  • 2342418
  • 2342419
  • 2342420
  • 2342421
  • 2342422
  • 57714_at
  • 62967_r_at
  • 7902345
  • A_14_P110762
  • A_23_P103172
  • A_23_P103180
  • A_24_P396327
  • GE552954
  • GO:0003824
  • GO:0005515
  • GO:0005737
  • GO:0006399
  • GO:0008033
  • GO:0008168
  • GO:0008175
  • GO:0016740
  • GO:0030488
  • GO:0031591
  • GO:0032259
  • GO:0140098
  • GO:1901135
  • HMNXSV003033785
  • HMNXSV003055430
  • Hs.283713.1.A1_3p_s_at
  • ILMN_1726842
  • PH_hs_0016785
  • PH_hs_0035811
  • TC01000772.hg
  • TC01004481.hg
  • TC01004482.hg
physicalEntity
referenceDatabase [ReferenceDatabase:2] UniProt
referenceGene
referenceTranscript
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • TYW3_HUMAN
  • B4DSP9
  • E9PGR7
  • Q5HYJ0
  • Q8N7L1
sequenceLength 259
species [Species:48887] Homo sapiens
stId uniprot:Q6IPR3
url http://purl.uniprot.org/uniprot/Q6IPR3
Cite Us!