UniProt:Q12690 RPL13A

chain
  • chain:1-199
checksum EA7CC5F1F3C0335A
comment
  • FUNCTION Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.SUBUNIT Component of the large ribosomal subunit (LSU). Mature yeast ribosomes consist of a small (40S) and a large (60S) subunit. The 40S small subunit contains 1 molecule of ribosomal RNA (18S rRNA) and 33 different proteins (encoded by 57 genes). The large 60S subunit contains 3 rRNA molecules (25S, 5.8S and 5S rRNA) and 46 different proteins (encoded by 81 genes) (PubMed:22096102, PubMed:9559554).SUBCELLULAR LOCATION Present with 133000 molecules/cell in log phase SD medium.MISCELLANEOUS There are 2 genes for eL13 in yeast.SIMILARITY Belongs to the eukaryotic ribosomal protein eL13 family.
crossReference
databaseName UniProt
dbId 99424
description
  • recommendedName: fullName evidence="5"Large ribosomal subunit protein eL13A alternativeName: fullName evidence="6"60S ribosomal protein L13-A
displayName UniProt:Q12690 RPL13A
geneName
  • RPL13A
  • YDL082W
identifier Q12690
isSequenceChanged false
keyword
  • 3D-structure
  • Cytoplasm
  • Phosphoprotein
  • Reference proteome
  • Ribonucleoprotein
  • Ribosomal protein
modified [InstanceEdit:9917590] Weiser, Joel, 2024-08-09
moleculeType Protein
name
  • RPL13A
otherIdentifier
  • 851477
  • GO:0002181
  • GO:0003723
  • GO:0003735
  • GO:0005198
  • GO:0005575
  • GO:0005737
  • GO:0005829
  • GO:0005840
  • GO:0006412
  • GO:0022625
  • GO:1990904
physicalEntity
referenceDatabase [ReferenceDatabase:2] UniProt
referenceGene
referenceTranscript
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • RL13A_YEAST
  • D6VRR7
sequenceLength 199
species [Species:68322] Saccharomyces cerevisiae
stId uniprot:Q12690
url http://purl.uniprot.org/uniprot/Q12690
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