Reactome | UniProt:Q04177 UTP5

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UniProt:Q04177 UTP5 Show undefined attributes

chain	chain:1-643
checksum	7A6F60C7C6F46C2A
comment	FUNCTION Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I together with a subset of U3 proteins required for transcription (t-UTPs).SUBUNIT Interacts with snoRNA U3. Interacts with MPP10. Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3. In the absence of snoRNA3, forms a complex with other t-UTPs. This complex can associate with pre-18S ribosomal RNAs.INTERACTION Associated with ribosomal chromatin, even in the absence of transcription.MISCELLANEOUS Present with 33100 molecules/cell in log phase SD medium.SIMILARITY Belongs to the UTP5 family.
created	[InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53
crossReference	[DatabaseIdentifier:12470286] RefSeq:NP_010686.1 [DatabaseIdentifier:12271307] PRO:Q04177 [DatabaseIdentifier:12141682] PDB:6ZQE [DatabaseIdentifier:12141683] PDB:6LQV [DatabaseIdentifier:12141681] PDB:6LQS [DatabaseIdentifier:12141680] PDB:6LQT [DatabaseIdentifier:12141692] PDB:6ZQD [DatabaseIdentifier:12141686] PDB:6ZQB [DatabaseIdentifier:12141678] PDB:7D4I [DatabaseIdentifier:12141685] PDB:6LQP [DatabaseIdentifier:12141691] PDB:6LQR [DatabaseIdentifier:12141684] PDB:6LQU [DatabaseIdentifier:12141687] PDB:7AJU [DatabaseIdentifier:12141693] PDB:6LQQ [DatabaseIdentifier:12141697] PDB:7D5T [DatabaseIdentifier:12141689] PDB:6ZQA [DatabaseIdentifier:12141673] PDB:7SUK [DatabaseIdentifier:12141694] PDB:6ZQC [DatabaseIdentifier:12141676] PDB:6ND4 [DatabaseIdentifier:12141679] PDB:5WLC [DatabaseIdentifier:12141677] PDB:9G33 [DatabaseIdentifier:12141695] PDB:7D63 [DatabaseIdentifier:12141690] PDB:7AJT [DatabaseIdentifier:12141698] PDB:6KE6 [DatabaseIdentifier:12141696] PDB:7D5S [DatabaseIdentifier:11762152] ENSEMBL:YDR398W_mRNA [DatabaseIdentifier:11639453] ENSEMBL:YDR398W [DatabaseIdentifier:11520520] ENSEMBL:YDR398W
databaseName	UniProt
dbId	254007
description	recommendedName: U3 small nucleolar RNA-associated protein 5 shortName: U3 snoRNA-associated protein 5 alternativeName: U three protein 5 alternativeName: U3 protein 5 required for transcription alternativeName: t-UTP5
displayName	UniProt:Q04177 UTP5
geneName	UTP5 YDR398W D9509.17
identifier	Q04177
isSequenceChanged	false
keyword	3D-structure Nucleus Reference proteome Repeat Ribonucleoprotein Ribosome biogenesis rRNA processing Transcription WD repeat
modified	[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
moleculeType	Protein
name	UTP5
otherIdentifier	852007 GO:0000462 GO:0003674 GO:0005515 GO:0005575 GO:0005634 GO:0005654 GO:0005730 GO:0006364 GO:0008150 GO:0009451 GO:0030490 GO:0031167 GO:0032040 GO:0033553 GO:0034455 GO:0042254 GO:0045943 GO:1990904
physicalEntity	[EntityWithAccessionedSequence:R-SCE-6790617] UTP5 [nucleoplasm] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-6790653] UTP5 [nucleoplasm] - Saccharomyces cerevisiae
referenceDatabase	[ReferenceDatabase:2] UniProt
referenceGene	[ReferenceDNASequence:12715390] UCSC:Q04177 UTP5 [ReferenceDNASequence:12098324] NCBI Gene:852007 UTP5 [ReferenceDNASequence:12014231] Monarch:852007 UTP5 [ReferenceDNASequence:11921060] KEGG:sce:YDR398W UTP5 [ReferenceDNASequence:11384442] BioGPS Gene:852007 UTP5
referenceTranscript	[ReferenceRNASequence:12651756] RefSeq:NM_001180706.1 UTP5
schemaClass	ReferenceGeneProduct
secondaryIdentifier	UTP5_YEAST D6VT31
sequenceLength	643
species	[Species:68322] Saccharomyces cerevisiae
stId	uniprot:Q04177
url	http://purl.uniprot.org/uniprot/Q04177

Referrals

(interactor)	[UndirectedInteraction:11297047] UniProt:P38333 <-> UniProt:Q04177 (IntAct)
(referenceEntity)	[EntityWithAccessionedSequence:R-SCE-6790617] UTP5 [nucleoplasm] [EntityWithAccessionedSequence:R-SCE-6790653] UTP5 [nucleoplasm]

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