Reactome | UniProt:Q02753 RPL21A

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UniProt:Q02753 RPL21A Show undefined attributes

chain	initiator methionine:1 chain:2-160
checksum	45286521C8473A72
comment	FUNCTION Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.SUBUNIT Component of the large ribosomal subunit (LSU). Mature yeast ribosomes consist of a small (40S) and a large (60S) subunit. The 40S small subunit contains 1 molecule of ribosomal RNA (18S rRNA) and 33 different proteins (encoded by 57 genes). The large 60S subunit contains 3 rRNA molecules (25S, 5.8S and 5S rRNA) and 46 different proteins (encoded by 81 genes) (PubMed:22096102, PubMed:9559554).SUBCELLULAR LOCATION There are 2 genes for eL21 in yeast.SIMILARITY Belongs to the eukaryotic ribosomal protein eL21 family.
crossReference	[DatabaseIdentifier:12142405] PDB:8CF5 [DatabaseIdentifier:12311358] RefSeq:NP_009750.1 [DatabaseIdentifier:12239644] PRO:Q02753 [DatabaseIdentifier:12142423] PDB:5ON6 [DatabaseIdentifier:12152564] PDB:8PFR [DatabaseIdentifier:12145008] PDB:6N8O [DatabaseIdentifier:12145010] PDB:6N8N [DatabaseIdentifier:12145012] PDB:5JCS [DatabaseIdentifier:12145011] PDB:7OH3 [DatabaseIdentifier:12142424] PDB:5TGM [DatabaseIdentifier:12144977] PDB:7TOP [DatabaseIdentifier:12142290] PDB:4V7R [DatabaseIdentifier:12142389] PDB:8CKU [DatabaseIdentifier:12144976] PDB:7V08 [DatabaseIdentifier:12142314] PDB:8CGN [DatabaseIdentifier:12142327] PDB:5MEI [DatabaseIdentifier:12144994] PDB:5APN [DatabaseIdentifier:12144990] PDB:8AGU [DatabaseIdentifier:12142351] PDB:8ZHB [DatabaseIdentifier:12142368] PDB:6TB3 [DatabaseIdentifier:12142339] PDB:8CIV [DatabaseIdentifier:12142303] PDB:4U55 [DatabaseIdentifier:12142298] PDB:5MC6 [DatabaseIdentifier:12144974] PDB:3JCT [DatabaseIdentifier:12144986] PDB:8AGZ [DatabaseIdentifier:12142347] PDB:3J6X [DatabaseIdentifier:12142336] PDB:4V8Z [DatabaseIdentifier:12144972] PDB:4V8T [DatabaseIdentifier:12144982] PDB:8AGX [DatabaseIdentifier:12142403] PDB:5DGE [DatabaseIdentifier:12142372] PDB:8ZH3 [DatabaseIdentifier:12150882] PDB:7R7A [DatabaseIdentifier:12142312] PDB:6Q8Y [DatabaseIdentifier:12142383] PDB:8P4V [DatabaseIdentifier:12142400] PDB:5DGV [DatabaseIdentifier:12144978] PDB:6YLH [DatabaseIdentifier:12144985] PDB:8AGW [DatabaseIdentifier:12142344] PDB:7MPI [DatabaseIdentifier:12145006] PDB:6N8M [DatabaseIdentifier:12142371] PDB:8ZGR [DatabaseIdentifier:12139467] PDB:4V91 [DatabaseIdentifier:12142301] PDB:5NDW [DatabaseIdentifier:12144998] PDB:7UQZ [DatabaseIdentifier:12142362] PDB:6XIR [DatabaseIdentifier:12142334] PDB:4V8Y [DatabaseIdentifier:12144999] PDB:5T6R [DatabaseIdentifier:12144968] PDB:6RZZ [DatabaseIdentifier:12142348] PDB:3J6Y [DatabaseIdentifier:12144996] PDB:7OF1 [DatabaseIdentifier:12142321] PDB:6TNU [DatabaseIdentifier:12142364] PDB:6XIQ [DatabaseIdentifier:12142338] PDB:8Z70 [DatabaseIdentifier:12142300] PDB:6I7O [DatabaseIdentifier:12145000] PDB:8HFR [DatabaseIdentifier:12144988] PDB:8BIP [DatabaseIdentifier:12140535] PDB:8Z71 [DatabaseIdentifier:12140964] PDB:4V5Z [DatabaseIdentifier:12142420] PDB:8CMJ [DatabaseIdentifier:12142305] PDB:4U4U [DatabaseIdentifier:12142394] PDB:5TGA [DatabaseIdentifier:12142320] PDB:5DAT [DatabaseIdentifier:12144987] PDB:6YLY [DatabaseIdentifier:12145002] PDB:8BJQ [DatabaseIdentifier:12144984] PDB:8AGV [DatabaseIdentifier:12142426] PDB:7ZUW [DatabaseIdentifier:12142322] PDB:9F9S [DatabaseIdentifier:12142306] PDB:4U56 [DatabaseIdentifier:12144979] PDB:6YLG [DatabaseIdentifier:12150862] PDB:7NAC [DatabaseIdentifier:12142345] PDB:6SNT [DatabaseIdentifier:12145004] PDB:6N8K [DatabaseIdentifier:12144995] PDB:6YLX [DatabaseIdentifier:12142391] PDB:8XU8 [DatabaseIdentifier:12142356] PDB:8ZGY [DatabaseIdentifier:12144973] PDB:6FT6 [DatabaseIdentifier:12142308] PDB:4U4Z [DatabaseIdentifier:12142404] PDB:5DGF [DatabaseIdentifier:12150868] PDB:7U0H [DatabaseIdentifier:12142292] PDB:8CG8 [DatabaseIdentifier:12142325] PDB:6HHQ [DatabaseIdentifier:12144997] PDB:6S05 [DatabaseIdentifier:12144983] PDB:5T62 [DatabaseIdentifier:12144989] PDB:8AGT [DatabaseIdentifier:12142307] PDB:4U4Y [DatabaseIdentifier:12144993] PDB:5APO [DatabaseIdentifier:12144970] PDB:8Y0U [DatabaseIdentifier:12140531] PDB:7B7D [DatabaseIdentifier:12142407] PDB:6T4Q [DatabaseIdentifier:12144992] PDB:7AZY [DatabaseIdentifier:12144991] PDB:6OIG [DatabaseIdentifier:12142353] PDB:8ZHC [DatabaseIdentifier:12142332] PDB:8K82 [DatabaseIdentifier:12142299] PDB:5NDV [DatabaseIdentifier:12144981] PDB:7UQB [DatabaseIdentifier:12144969] PDB:4V7F [DatabaseIdentifier:12142341] PDB:7MPJ [DatabaseIdentifier:12142342] PDB:7NRC [DatabaseIdentifier:12142343] PDB:7NRD [DatabaseIdentifier:12144971] PDB:6QIK [DatabaseIdentifier:12145001] PDB:6M62 [DatabaseIdentifier:12142330] PDB:5TBW [DatabaseIdentifier:12144975] PDB:7UOO [DatabaseIdentifier:12142357] PDB:3J77 [DatabaseIdentifier:12142313] PDB:5DC3 [DatabaseIdentifier:12142315] PDB:4U6F [DatabaseIdentifier:12142346] PDB:3J78 [DatabaseIdentifier:12142319] PDB:4V88 [DatabaseIdentifier:12145007] PDB:6N8L [DatabaseIdentifier:12144980] PDB:7TOO [DatabaseIdentifier:12145005] PDB:6N8J [DatabaseIdentifier:12142324] PDB:8EUB [DatabaseIdentifier:12144953] PDB:5GAK [DatabaseIdentifier:12142416] PDB:4U4R [DatabaseIdentifier:12144964] PDB:6R86 [DatabaseIdentifier:12142410] PDB:4U50 [DatabaseIdentifier:12142382] PDB:6Z6K [DatabaseIdentifier:12142363] PDB:8EVQ [DatabaseIdentifier:12142297] PDB:8P85 [DatabaseIdentifier:12142328] PDB:8UTI [DatabaseIdentifier:12142380] PDB:7ZRS [DatabaseIdentifier:12142335] PDB:7N8B [DatabaseIdentifier:12144960] PDB:6QTZ [DatabaseIdentifier:12152562] PDB:8P8M [DatabaseIdentifier:12142326] PDB:6T7T [DatabaseIdentifier:12142401] PDB:8CDL [DatabaseIdentifier:12142293] PDB:5JUP [DatabaseIdentifier:12142392] PDB:6GQB [DatabaseIdentifier:12142425] PDB:7ZUX [DatabaseIdentifier:12142379] PDB:8EVP [DatabaseIdentifier:12142340] PDB:8T30 [DatabaseIdentifier:12142361] PDB:8T3B [DatabaseIdentifier:12142395] PDB:5FCJ [DatabaseIdentifier:12142354] PDB:6GQ1 [DatabaseIdentifier:12150864] PDB:6ELZ [DatabaseIdentifier:12142402] PDB:5FCI [DatabaseIdentifier:12142385] PDB:8CCS [DatabaseIdentifier:12142415] PDB:7ZW0 [DatabaseIdentifier:12142422] PDB:4U3U [DatabaseIdentifier:12142411] PDB:4U51 [DatabaseIdentifier:12142318] PDB:6S47 [DatabaseIdentifier:12150869] PDB:6EM5 [DatabaseIdentifier:12142316] PDB:8BN3 [DatabaseIdentifier:12142296] PDB:5JUT [DatabaseIdentifier:12142323] PDB:6T83 [DatabaseIdentifier:12140536] PDB:8YLR [DatabaseIdentifier:12152563] PDB:4V4B [DatabaseIdentifier:12150872] PDB:7BT6 [DatabaseIdentifier:12144965] PDB:6HD7 [DatabaseIdentifier:12142417] PDB:4U53 [DatabaseIdentifier:12150861] PDB:7BTB [DatabaseIdentifier:12142302] PDB:5JUO [DatabaseIdentifier:12150878] PDB:7OHT [DatabaseIdentifier:12142359] PDB:8T3A [DatabaseIdentifier:12144957] PDB:5H4P [DatabaseIdentifier:12142366] PDB:8T3E [DatabaseIdentifier:12142365] PDB:8EVR [DatabaseIdentifier:12142399] PDB:4U3N [DatabaseIdentifier:12144962] PDB:6R84 [DatabaseIdentifier:12142370] PDB:8T3D [DatabaseIdentifier:12142294] PDB:5JUS [DatabaseIdentifier:12144956] PDB:9F58 [DatabaseIdentifier:12144966] PDB:6RI5 [DatabaseIdentifier:12142381] PDB:8T2Z [DatabaseIdentifier:12140532] PDB:8YLD [DatabaseIdentifier:12144967] PDB:8AAF [DatabaseIdentifier:12144958] PDB:9OFV [DatabaseIdentifier:12142396] PDB:8PNN [DatabaseIdentifier:12142386] PDB:8BQX [DatabaseIdentifier:12144959] PDB:7ZS5 [DatabaseIdentifier:11445502] ENSEMBL:YBR191W [DatabaseIdentifier:11532407] ENSEMBL:YBR191W [DatabaseIdentifier:11655106] ENSEMBL:YBR191W_mRNA [DatabaseIdentifier:12142337] PDB:7ZPQ [DatabaseIdentifier:12142350] PDB:8EWC [DatabaseIdentifier:12142367] PDB:8T3F [DatabaseIdentifier:12142397] PDB:4U3M [DatabaseIdentifier:12142378] PDB:5OBM [DatabaseIdentifier:12142413] PDB:4U4Q [DatabaseIdentifier:12142311] PDB:8UT0 [DatabaseIdentifier:12152561] PDB:8P8N [DatabaseIdentifier:12142352] PDB:8BQD [DatabaseIdentifier:12142414] PDB:4U52 [DatabaseIdentifier:12144954] PDB:7UG6 [DatabaseIdentifier:12142418] PDB:5M1J [DatabaseIdentifier:12142349] PDB:8EWB [DatabaseIdentifier:12142421] PDB:8CEH [DatabaseIdentifier:12142377] PDB:8T2Y [DatabaseIdentifier:12142358] PDB:8EVS [DatabaseIdentifier:12142409] PDB:4U4O [DatabaseIdentifier:12142295] PDB:5JUU [DatabaseIdentifier:12144963] PDB:6R87 [DatabaseIdentifier:12144951] PDB:7OHQ [DatabaseIdentifier:12142333] PDB:8P9A [DatabaseIdentifier:12142384] PDB:6Z6J [DatabaseIdentifier:12144952] PDB:8P8U [DatabaseIdentifier:12142309] PDB:6SV4 [DatabaseIdentifier:12142369] PDB:8T3C [DatabaseIdentifier:12144955] PDB:6QT0 [DatabaseIdentifier:12142388] PDB:6GQV [DatabaseIdentifier:12142329] PDB:6T7I [DatabaseIdentifier:12142398] PDB:8CDR [DatabaseIdentifier:12142375] PDB:8T2X [DatabaseIdentifier:12142374] PDB:6WOO [DatabaseIdentifier:12142304] PDB:5LYB [DatabaseIdentifier:12142393] PDB:8K2D [DatabaseIdentifier:12144961] PDB:7Z34 [DatabaseIdentifier:12142419] PDB:4V6I [DatabaseIdentifier:12142408] PDB:4U4N [DatabaseIdentifier:12142412] PDB:5NDG [DatabaseIdentifier:12142331] PDB:5I4L [DatabaseIdentifier:12142360] PDB:8EVT
databaseName	UniProt
dbId	99461
description	recommendedName: fullName evidence="5"Large ribosomal subunit protein eL21A alternativeName: fullName evidence="6"60S ribosomal protein L21-A
displayName	UniProt:Q02753 RPL21A
geneName	RPL21A URP1 YBR191W YBR1401
identifier	Q02753
isSequenceChanged	false
keyword	3D-structure Cytoplasm Isopeptide bond Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation
modified	[InstanceEdit:9963647] Weiser, Joel, 2025-08-15
moleculeType	Protein
name	RPL21A
otherIdentifier	852489 GO:0002181 GO:0003735 GO:0005198 GO:0005575 GO:0005737 GO:0005829 GO:0005840 GO:0006412 GO:0015934 GO:0022625 GO:1990904
physicalEntity	[EntityWithAccessionedSequence:R-SCE-9633214] RPL21A [cytosol] - Saccharomyces cerevisiae
referenceDatabase	[ReferenceDatabase:2] UniProt
referenceGene	[ReferenceDNASequence:11311177] BioGPS Gene:852489 RPL21A [ReferenceDNASequence:12670392] UCSC:Q02753 RPL21A [ReferenceDNASequence:11854844] KEGG:sce:YBR191W RPL21A [ReferenceDNASequence:11940966] Monarch:852489 RPL21A [ReferenceDNASequence:12025059] NCBI Gene:852489 RPL21A
referenceTranscript	[ReferenceRNASequence:12493443] RefSeq:NM_001178539.1 RPL21A
schemaClass	ReferenceGeneProduct
secondaryIdentifier	RL21A_YEAST D6VQI5
sequenceLength	160
species	[Species:68322] Saccharomyces cerevisiae
stId	uniprot:Q02753
url	http://purl.uniprot.org/uniprot/Q02753

Referrals

(referenceEntity)

[EntityWithAccessionedSequence:R-SCE-9633214] RPL21A [cytosol]

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