Reactome | UniProt:Q01113 IL9R

Schema > ReferenceGeneProduct > Entries

UniProt:Q01113 IL9R Show undefined attributes

chain	signal peptide:1-40 chain:41-521
checksum	07C40436466173F3
comment	FUNCTION Plays an important role in the immune response against parasites by acting as a receptor of IL9.SUBUNIT Interacts with IL9.INTERACTION The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.DOMAIN The box 1 motif is required for JAK interaction and/or activation.MISCELLANEOUS The gene coding for this protein is located in the pseudoautosomal region 2 (PAR2) of X and Y chromosomes.SIMILARITY Belongs to the type I cytokine receptor family. Type 4 subfamily.SEQUENCE CAUTION Extended N-terminus.
crossReference	[DatabaseIdentifier:12435540] RefSeq:NP_789743.2 [DatabaseIdentifier:12435541] RefSeq:NP_002177.2 [DatabaseIdentifier:12294122] Pharos - Targets:Q01113 [DatabaseIdentifier:12256446] PRO:Q01113 [DatabaseIdentifier:12138152] PDB:7OX5 [DatabaseIdentifier:12133956] OpenTargets:ENSG00000124334 [DatabaseIdentifier:11849261] HPA:ENSG00000124334-IL9R [DatabaseIdentifier:11812070] GlyGen:Q01113 [DatabaseIdentifier:11796293] GeneCards:IL9R [DatabaseIdentifier:11780210] Guide to Pharmacology - Targets:1699 [DatabaseIdentifier:11737348] ENSEMBL:ENST00000369423 [DatabaseIdentifier:11737347] ENSEMBL:ENST00000244174 [DatabaseIdentifier:11614648] ENSEMBL:ENSP00000358431 [DatabaseIdentifier:11614649] ENSEMBL:ENSP00000244174 [DatabaseIdentifier:11503210] ENSEMBL:ENSG00000124334
databaseName	UniProt
dbId	57291
description	recommendedName: Interleukin-9 receptor shortName: IL-9 receptor shortName: IL-9R cdAntigenNameCD129/cdAntigenName
displayName	UniProt:Q01113 IL9R
geneName	IL9R
identifier	Q01113
isSequenceChanged	false
keyword	3D-structure Alternative splicing Cell membrane Glycoprotein Membrane Proteomics identification Receptor Reference proteome Secreted Signal Transmembrane Transmembrane helix
modified	[InstanceEdit:9983091] Weiser, Joel, 2026-02-20
moleculeType	Protein
name	IL9R
otherIdentifier	11741876_a_at 11741877_s_at 11748692_a_at 17116694 208164_PM_s_at 208164_s_at 214950_PM_at 214950_at 217212_PM_s_at 217212_s_at 3273203 3273207 3581 3674813 3674814 3674815 3674816 3674817 3674818 3674819 3674820 3674821 3674822 3674823 3674825 3674827 3674833 3674835 3674839 3795657 3996972 3996978 3996979 3996980 3996983 3996984 3996985 3996986 3996987 3996988 3996989 3996990 3996991 3996992 3996993 3996994 3996996 3996997 3996998 3996999 3997000 3997001 3997002 3997003 3997004 3997005 3997006 3997007 3997008 3997009 3997011 3997013 3997015 3997016 3997017 3997018 3997019 3997020 4032782 4032788 4032789 4032790 4032793 4032794 4032795 4032796 4032797 4032798 4032799 4032800 4032801 4032802 4032803 4032804 4032806 4032807 4032808 4032809 4032810 4032811 4032812 4032813 4032814 4032815 4032816 4032817 4032818 4032819 4032821 4032823 4032825 4032826 4032827 4032828 4032829 4032830 629_at 8171052 8176972 938_at A_23_P34066 GE58113 GO:0002376 GO:0004896 GO:0004919 GO:0005515 GO:0005576 GO:0005615 GO:0005886 GO:0007165 GO:0009897 GO:0016020 GO:0016064 GO:0019221 GO:0019983 GO:0038113 GO:0042127 HMNXSV003031551 HMNXSV003053767 Hs.1702.1.S1_3p_at Hs.247991.0.S1_3p_s_at ILMN_1692893 ILMN_1794686 ILMN_1814153 L39064_rna1_at PH_hs_0033154 TC0X001949.hg TC0X002325.hg TC0Y000355.hg g4504684_3p_a_at
physicalEntity	[EntityWithAccessionedSequence:R-HSA-449790] IL9R [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-8985904] p-Y407-IL9R [plasma membrane] - Homo sapiens
referenceDatabase	[ReferenceDatabase:2] UniProt
referenceGene	[ReferenceDNASequence:12758745] UCSC:Q01113 IL9R [ReferenceDNASequence:12118168] OMIM:300007 IL9R [ReferenceDNASequence:12082706] NCBI Gene:3581 IL9R [ReferenceDNASequence:11998613] Monarch:3581 IL9R [ReferenceDNASequence:11907058] KEGG:hsa:3581 IL9R [ReferenceDNASequence:11828001] HGNC:6030 IL9R [ReferenceDNASequence:11439722] dbSNP Gene:3581 IL9R [ReferenceDNASequence:11425491] CTD Gene:3581 IL9R [ReferenceDNASequence:11402258] COSMIC - genes:IL9R IL9R [ReferenceDNASequence:11368824] BioGPS Gene:3581 IL9R [ReferenceDNASequence:ensembl:ENSG00000124334] ENSEMBL:ENSG00000124334 IL9R
referenceTranscript	[ReferenceRNASequence:12617061] RefSeq:NM_176786.2 IL9R [ReferenceRNASequence:12617062] RefSeq:NM_002186.2 IL9R
schemaClass	ReferenceGeneProduct
secondaryIdentifier	IL9R_HUMAN B9ZVT0 Q14634 Q8WWU1 Q96TF0
sequenceLength	521
species	[Species:48887] Homo sapiens
stId	uniprot:Q01113
url	http://purl.uniprot.org/uniprot/Q01113

Referrals

(interactor)	[UndirectedInteraction:11260593] UniProt:Q01113 <-> UniProt:Q9NUE0 (IntAct) [UndirectedInteraction:11260591] UniProt:Q01113 <-> UniProt:Q8NC67 (IntAct) [UndirectedInteraction:11260587] UniProt:Q01113 <-> UniProt:Q86X29 (IntAct) [UndirectedInteraction:11260585] UniProt:Q01113 <-> UniProt:P63104 (IntAct) [UndirectedInteraction:11240969] UniProt:Q6NUM9 <-> UniProt:Q01113 (IntAct)
(referenceEntity)	[EntityWithAccessionedSequence:R-HSA-449790] IL9R [plasma membrane] [EntityWithAccessionedSequence:R-HSA-8985904] p-Y407-IL9R [plasma membrane]
(referenceSequence)	[ModifiedResidue:8985980] O4'-phospho-L-tyrosine at 407