Reactome | UniProt:P62945 RPL41

Schema > ReferenceGeneProduct > Entries

UniProt:P62945 RPL41 Show undefined attributes

chain	chain:1-25
checksum	9AD629C69ECC039E
comment	FUNCTION Component of the small ribosomal subunit (Probable) (Ref.8). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399). Interacts with the beta subunit of protein kinase CKII and stimulates phosphorylation of DNA topoisomerase II alpha by CKII (PubMed:9299532).SUBUNIT Component of the small ribosomal subunit.INTERACTION Initially thought to be part of the large ribosomal subunit. Crystal structures show eS32/eL41 to be a small ribosomal subunit forming a bridge at the interface of the 2 subunits.SIMILARITY Belongs to the eukaryotic ribosomal protein eS32 family.CAUTION There are multiple pseudogenes of this gene dispersed through the genome.
crossReference	[DatabaseIdentifier:12148697] PDB:4V6X [DatabaseIdentifier:12370190] RefSeq:NP_001030344.1 [DatabaseIdentifier:12370191] RefSeq:NP_066927.1 [DatabaseIdentifier:12286143] Pharos - Targets:P62945 [DatabaseIdentifier:12265780] PRO:P62945 [DatabaseIdentifier:12148947] PDB:7F5S [DatabaseIdentifier:12148788] PDB:6IP6 [DatabaseIdentifier:12148732] PDB:7A09 [DatabaseIdentifier:12148744] PDB:8IFE [DatabaseIdentifier:12148771] PDB:7TQL [DatabaseIdentifier:12148693] PDB:8XP3 [DatabaseIdentifier:12148750] PDB:7XNY [DatabaseIdentifier:12148700] PDB:8PJ1 [DatabaseIdentifier:12148733] PDB:6XA1 [DatabaseIdentifier:12148768] PDB:8QOI [DatabaseIdentifier:12148708] PDB:8G6J [DatabaseIdentifier:12148745] PDB:7XNX [DatabaseIdentifier:12148724] PDB:8PJ3 [DatabaseIdentifier:12148676] PDB:8UJB [DatabaseIdentifier:12148680] PDB:9B0R [DatabaseIdentifier:12148743] PDB:9ED0 [DatabaseIdentifier:12156081] PDB:6ZOK [DatabaseIdentifier:12148690] PDB:9B0S [DatabaseIdentifier:12148718] PDB:9AZC [DatabaseIdentifier:12148691] PDB:8UIY [DatabaseIdentifier:12148682] PDB:8Y0W [DatabaseIdentifier:12148729] PDB:6Y2L [DatabaseIdentifier:12148675] PDB:6OLI [DatabaseIdentifier:12148926] PDB:6Y6X [DatabaseIdentifier:12148785] PDB:8YOO [DatabaseIdentifier:12148678] PDB:8G61 [DatabaseIdentifier:12148777] PDB:5AJ0 [DatabaseIdentifier:12148765] PDB:6Z6L [DatabaseIdentifier:12148673] PDB:8PPL [DatabaseIdentifier:12148761] PDB:8XSX [DatabaseIdentifier:12148719] PDB:5OA3 [DatabaseIdentifier:12148696] PDB:9B0H [DatabaseIdentifier:12148699] PDB:6Y0G [DatabaseIdentifier:12148672] PDB:8G5Z [DatabaseIdentifier:12148782] PDB:8YOP [DatabaseIdentifier:12148757] PDB:8XSY [DatabaseIdentifier:12146422] PDB:6ZMO [DatabaseIdentifier:12148677] PDB:8XXM [DatabaseIdentifier:12148714] PDB:5LKS [DatabaseIdentifier:12148775] PDB:8GLP [DatabaseIdentifier:12148792] PDB:8UIK [DatabaseIdentifier:12148712] PDB:6OLZ [DatabaseIdentifier:12148741] PDB:9AZS [DatabaseIdentifier:12148746] PDB:5VYC [DatabaseIdentifier:12148685] PDB:8Y0X [DatabaseIdentifier:12148751] PDB:6ZMW [DatabaseIdentifier:12148727] PDB:8PJ6 [DatabaseIdentifier:12148787] PDB:9G8O [DatabaseIdentifier:12148698] PDB:9B0N [DatabaseIdentifier:12148716] PDB:6QZP [DatabaseIdentifier:12148694] PDB:9B0J [DatabaseIdentifier:12148772] PDB:7R4X [DatabaseIdentifier:12148735] PDB:9BLN [DatabaseIdentifier:12148770] PDB:8K2C [DatabaseIdentifier:12148764] PDB:6Z6M [DatabaseIdentifier:12148679] PDB:9B0Q [DatabaseIdentifier:12148736] PDB:6ZLW [DatabaseIdentifier:12148722] PDB:8PJ5 [DatabaseIdentifier:12148704] PDB:4UG0 [DatabaseIdentifier:12148681] PDB:5A2Q [DatabaseIdentifier:12148695] PDB:9B0G [DatabaseIdentifier:12148789] PDB:6IP5 [DatabaseIdentifier:12148739] PDB:7QP6 [DatabaseIdentifier:12148790] PDB:6IP8 [DatabaseIdentifier:12148688] PDB:8UIZ [DatabaseIdentifier:12148686] PDB:9B0P [DatabaseIdentifier:12148763] PDB:8T4S [DatabaseIdentifier:12148749] PDB:8IFD [DatabaseIdentifier:12148674] PDB:8XXL [DatabaseIdentifier:12148936] PDB:6W6L [DatabaseIdentifier:12148684] PDB:8G60 [DatabaseIdentifier:12148689] PDB:8UJ9 [DatabaseIdentifier:12148730] PDB:6ZME [DatabaseIdentifier:12148740] PDB:7QP7 [DatabaseIdentifier:12148930] PDB:7QVP [DatabaseIdentifier:12148783] PDB:9G8M [DatabaseIdentifier:12148687] PDB:9B11 [DatabaseIdentifier:12148786] PDB:6Y57 [DatabaseIdentifier:12148723] PDB:8PJ2 [DatabaseIdentifier:12154015] PDB:6YBW [DatabaseIdentifier:12148683] PDB:9B0O [DatabaseIdentifier:12148721] PDB:9BKD [DatabaseIdentifier:12148710] PDB:8ZDB [DatabaseIdentifier:12148703] PDB:8UKB [DatabaseIdentifier:12148692] PDB:8XP2 [DatabaseIdentifier:12148737] PDB:6ZM7 [DatabaseIdentifier:12148769] PDB:7K5I [DatabaseIdentifier:12146421] PDB:6ZMI [DatabaseIdentifier:11473145] ENSEMBL:ENSG00000229117 [DatabaseIdentifier:11571150] ENSEMBL:ENSP00000420821 [DatabaseIdentifier:11571151] ENSEMBL:ENSP00000449026 [DatabaseIdentifier:11693849] ENSEMBL:ENST00000501597 [DatabaseIdentifier:11693850] ENSEMBL:ENST00000546591 [DatabaseIdentifier:11788251] GeneCards:RPL41 [DatabaseIdentifier:11841307] HPA:ENSG00000229117-RPL41 [DatabaseIdentifier:12125869] OpenTargets:ENSG00000229117 [DatabaseIdentifier:12148658] PDB:8JDM [DatabaseIdentifier:12148671] PDB:6OLG [DatabaseIdentifier:12148661] PDB:8UJK [DatabaseIdentifier:12148666] PDB:8PPK [DatabaseIdentifier:12148664] PDB:8UJJ [DatabaseIdentifier:12148657] PDB:8JDL [DatabaseIdentifier:12148659] PDB:8JDJ [DatabaseIdentifier:12148669] PDB:6OLE [DatabaseIdentifier:12148670] PDB:8XXN [DatabaseIdentifier:12148663] PDB:9C3H [DatabaseIdentifier:12148667] PDB:6OLF [DatabaseIdentifier:12148662] PDB:6OM0 [DatabaseIdentifier:12148665] PDB:8G5Y [DatabaseIdentifier:12148668] PDB:9B0W [DatabaseIdentifier:12148660] PDB:8JDK [DatabaseIdentifier:12148709] PDB:6OM7 [DatabaseIdentifier:12148720] PDB:8PJ4 [DatabaseIdentifier:12148784] PDB:6ZON [DatabaseIdentifier:12148766] PDB:6Z6N [DatabaseIdentifier:12148767] PDB:6ZOJ [DatabaseIdentifier:12148793] PDB:9B0F [DatabaseIdentifier:12148715] PDB:9AZN [DatabaseIdentifier:12148759] PDB:8XSZ [DatabaseIdentifier:12148726] PDB:6G5H [DatabaseIdentifier:12148780] PDB:6ZP4 [DatabaseIdentifier:12148742] PDB:6ZVJ [DatabaseIdentifier:12148738] PDB:8OZ0
databaseName	UniProt
dbId	72477
description	recommendedName: fullName evidence="6"Small ribosomal subunit protein eS32 alternativeName: 60S ribosomal protein L41 alternativeName: HG12 alternativeName: fullName evidence="4"Large ribosomal subunit protein eL41
displayName	UniProt:P62945 RPL41
geneName	RPL41
identifier	P62945
isSequenceChanged	false
keyword	3D-structure Cytoplasm Reference proteome Ribonucleoprotein Ribosomal protein
modified	[InstanceEdit:9917590] Weiser, Joel, 2024-08-09
moleculeType	Protein
name	RPL41
otherIdentifier	11721113_x_at 11757355_x_at 16752477 17118277 201492_PM_s_at 201492_s_at 2810098 2810099 2810100 3026346 3026347 3026348 32466_at 3417346 3417347 3417348 3417349 3417350 3417351 3417353 3417354 3417355 3417357 3417358 3417359 3417360 3465758 3465759 3465760 3585540 3585542 3752156 3879737 3879738 3959291 3959292 6171 7956159 7965467 7982129 8061364 8075691 8105432 A_14_P113079 A_14_P115127 A_23_P128067 GE80308 GO:0002181 GO:0003723 GO:0003730 GO:0003735 GO:0005198 GO:0005515 GO:0005737 GO:0005783 GO:0005829 GO:0005840 GO:0006412 GO:0022625 GO:0048027 GO:1990904 ILMN_1710001 ILMN_2331890 PH_hs_0029972 TC12000502.hg TC12001813.hg TC12002389.hg TC15000130.hg TC20000146.hg Z12962_at g10863874_3p_s_at
physicalEntity	[EntityWithAccessionedSequence:R-HSA-72478] RPL41 [cytosol] - Homo sapiens
referenceDatabase	[ReferenceDatabase:2] UniProt
referenceGene	[ReferenceDNASequence:ensembl:ENSG00000229117] ENSEMBL:ENSG00000229117 RPL41 [ReferenceDNASequence:12687316] UCSC:P62945 RPL41 [ReferenceDNASequence:11338294] BioGPS Gene:6171 RPL41 [ReferenceDNASequence:11392735] COSMIC - genes:RPL41 RPL41 [ReferenceDNASequence:11414415] CTD Gene:6171 RPL41 [ReferenceDNASequence:11428578] dbSNP Gene:6171 RPL41 [ReferenceDNASequence:11819902] HGNC:10354 RPL41 [ReferenceDNASequence:11879225] KEGG:hsa:6171 RPL41 [ReferenceDNASequence:11968083] Monarch:6171 RPL41 [ReferenceDNASequence:12052176] NCBI Gene:6171 RPL41 [ReferenceDNASequence:12111046] OMIM:613315 RPL41
referenceTranscript	[ReferenceRNASequence:12552002] RefSeq:NM_001035267.2 RPL41 [ReferenceRNASequence:12552001] RefSeq:NM_021104.2 RPL41
schemaClass	ReferenceGeneProduct
secondaryIdentifier	RS32_HUMAN A6NG21 P28751
sequenceLength	25
species	[Species:48887] Homo sapiens
stId	uniprot:P62945
url	http://purl.uniprot.org/uniprot/P62945

Referrals

(referenceEntity)	[EntityWithAccessionedSequence:R-HSA-72478] RPL41 [cytosol]
(interactor)	[UndirectedInteraction:11138433] UniProt:P63244 <-> UniProt:P62945 (IntAct)

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