Reactome | UniProt:P62861 FAU

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UniProt:P62861 FAU Show undefined attributes

chain	chain:1-133 chain:1-74 chain:75-133
checksum	5D2F81F2A355B559
comment	FUNCTION May have pro-apoptotic activity.FUNCTION Component of the 40S subunit of the ribosome. Contributes to the assembly and function of 40S ribosomal subunits.SUBUNIT Component of the 40S subunit of the ribosome.INTERACTION FUBI is cleaved from ribosomal protein S30 by the deubiquitinase USP36 before the assembly of ribosomal protein S30 into pre-40S ribosomal particles. FUBI removal from ribosomal protein S30 is a crucial event for the final maturation of pre-40S particles.MISCELLANEOUS FAU encodes a fusion protein consisting of the ubiquitin-like protein FUBI at the N terminus and ribosomal protein S30 at the C terminus.MISCELLANEOUS Lacks the typical lysine residues that participate in Ub's polyubiquitination. However contains a C-terminal di-glycine signature after its proteolytic separation from ribosomal protein S30 and could theoretically be conjugated onto target proteins.SIMILARITY In the N-terminal section; belongs to the ubiquitin family.SIMILARITY In the C-terminal section; belongs to the eukaryotic ribosomal protein eS30 family.
crossReference	[DatabaseIdentifier:12148709] PDB:6OM7 [DatabaseIdentifier:12368387] RefSeq:NP_001988.1 [DatabaseIdentifier:12285637] Pharos - Targets:P62861 [DatabaseIdentifier:12148778] PDB:6ZXF [DatabaseIdentifier:12156081] PDB:6ZOK [DatabaseIdentifier:12148783] PDB:9G8M [DatabaseIdentifier:12148782] PDB:8YOP [DatabaseIdentifier:12148787] PDB:9G8O [DatabaseIdentifier:12148784] PDB:6ZON [DatabaseIdentifier:12148775] PDB:8GLP [DatabaseIdentifier:12148780] PDB:6ZP4 [DatabaseIdentifier:12148786] PDB:6Y57 [DatabaseIdentifier:12148785] PDB:8YOO [DatabaseIdentifier:12148771] PDB:7TQL [DatabaseIdentifier:12148790] PDB:6IP8 [DatabaseIdentifier:12148776] PDB:6ZXG [DatabaseIdentifier:12148793] PDB:9B0F [DatabaseIdentifier:12148777] PDB:5AJ0 [DatabaseIdentifier:12148773] PDB:6ZXE [DatabaseIdentifier:12148789] PDB:6IP5 [DatabaseIdentifier:12148792] PDB:8UIK [DatabaseIdentifier:12148779] PDB:6ZXH [DatabaseIdentifier:12148788] PDB:6IP6 [DatabaseIdentifier:12148772] PDB:7R4X [DatabaseIdentifier:12148774] PDB:6ZXD [DatabaseIdentifier:12148791] PDB:5FLX [DatabaseIdentifier:12178805] PDB:8BS3 [DatabaseIdentifier:12148725] PDB:6G5I [DatabaseIdentifier:12148730] PDB:6ZME [DatabaseIdentifier:12148757] PDB:8XSY [DatabaseIdentifier:12148675] PDB:6OLI [DatabaseIdentifier:12148685] PDB:8Y0X [DatabaseIdentifier:12148763] PDB:8T4S [DatabaseIdentifier:12148706] PDB:6G53 [DatabaseIdentifier:12148721] PDB:9BKD [DatabaseIdentifier:12148759] PDB:8XSZ [DatabaseIdentifier:12148717] PDB:5T2C [DatabaseIdentifier:12148735] PDB:9BLN [DatabaseIdentifier:12148704] PDB:4UG0 [DatabaseIdentifier:12148694] PDB:9B0J [DatabaseIdentifier:12148770] PDB:8K2C [DatabaseIdentifier:12148768] PDB:8QOI [DatabaseIdentifier:12148753] PDB:7WTW [DatabaseIdentifier:12148672] PDB:8G5Z [DatabaseIdentifier:12178804] PDB:2L7R [DatabaseIdentifier:12148747] PDB:6ZMT [DatabaseIdentifier:12148750] PDB:7XNY [DatabaseIdentifier:12148761] PDB:8XSX [DatabaseIdentifier:12148731] PDB:6ZUO [DatabaseIdentifier:12148739] PDB:7QP6 [DatabaseIdentifier:12148732] PDB:7A09 [DatabaseIdentifier:12148697] PDB:4V6X [DatabaseIdentifier:12148686] PDB:9B0P [DatabaseIdentifier:12148766] PDB:6Z6N [DatabaseIdentifier:12148741] PDB:9AZS [DatabaseIdentifier:12148727] PDB:8PJ6 [DatabaseIdentifier:12153090] PDB:7WTS [DatabaseIdentifier:12148738] PDB:8OZ0 [DatabaseIdentifier:12148684] PDB:8G60 [DatabaseIdentifier:12148720] PDB:8PJ4 [DatabaseIdentifier:12148679] PDB:9B0Q [DatabaseIdentifier:12156080] PDB:6FEC [DatabaseIdentifier:12148724] PDB:8PJ3 [DatabaseIdentifier:12148756] PDB:7WTZ [DatabaseIdentifier:12148699] PDB:6Y0G [DatabaseIdentifier:12148688] PDB:8UIZ [DatabaseIdentifier:12148708] PDB:8G6J [DatabaseIdentifier:12148715] PDB:9AZN [DatabaseIdentifier:12148726] PDB:6G5H [DatabaseIdentifier:12148681] PDB:5A2Q [DatabaseIdentifier:12148748] PDB:6ZN5 [DatabaseIdentifier:12148689] PDB:8UJ9 [DatabaseIdentifier:12148760] PDB:7WTX [DatabaseIdentifier:12148705] PDB:6G51 [DatabaseIdentifier:12148695] PDB:9B0G [DatabaseIdentifier:12148762] PDB:6G18 [DatabaseIdentifier:12148743] PDB:9ED0 [DatabaseIdentifier:12148751] PDB:6ZMW [DatabaseIdentifier:12148742] PDB:6ZVJ [DatabaseIdentifier:12148678] PDB:8G61 [DatabaseIdentifier:12148769] PDB:7K5I [DatabaseIdentifier:12146421] PDB:6ZMI [DatabaseIdentifier:12148744] PDB:8IFE [DatabaseIdentifier:12148702] PDB:6G4W [DatabaseIdentifier:12148764] PDB:6Z6M [DatabaseIdentifier:12148718] PDB:9AZC [DatabaseIdentifier:12148700] PDB:8PJ1 [DatabaseIdentifier:12148765] PDB:6Z6L [DatabaseIdentifier:12148736] PDB:6ZLW [DatabaseIdentifier:12148680] PDB:9B0R [DatabaseIdentifier:12148671] PDB:6OLG [DatabaseIdentifier:12148740] PDB:7QP7 [DatabaseIdentifier:12148677] PDB:8XXM [DatabaseIdentifier:12148716] PDB:6QZP [DatabaseIdentifier:12148683] PDB:9B0O [DatabaseIdentifier:12148737] PDB:6ZM7 [DatabaseIdentifier:12148719] PDB:5OA3 [DatabaseIdentifier:12146423] PDB:6ZVH [DatabaseIdentifier:12148728] PDB:7WU0 [DatabaseIdentifier:12148701] PDB:6G4S [DatabaseIdentifier:12148690] PDB:9B0S [DatabaseIdentifier:12148682] PDB:8Y0W [DatabaseIdentifier:12148674] PDB:8XXL [DatabaseIdentifier:12148752] PDB:7WTV [DatabaseIdentifier:12148691] PDB:8UIY [DatabaseIdentifier:12148712] PDB:6OLZ [DatabaseIdentifier:12148755] PDB:7WTU [DatabaseIdentifier:12148754] PDB:7WTT [DatabaseIdentifier:12154015] PDB:6YBW [DatabaseIdentifier:12148729] PDB:6Y2L [DatabaseIdentifier:12148745] PDB:7XNX [DatabaseIdentifier:12148710] PDB:8ZDB [DatabaseIdentifier:12148696] PDB:9B0H [DatabaseIdentifier:12148698] PDB:9B0N [DatabaseIdentifier:12148723] PDB:8PJ2 [DatabaseIdentifier:12148758] PDB:6ZV6 [DatabaseIdentifier:12148722] PDB:8PJ5 [DatabaseIdentifier:12148693] PDB:8XP3 [DatabaseIdentifier:11472394] ENSEMBL:ENSG00000149806 [DatabaseIdentifier:11570016] ENSEMBL:ENSP00000431822 [DatabaseIdentifier:11570018] ENSEMBL:ENSP00000434440 [DatabaseIdentifier:11570017] ENSEMBL:ENSP00000435370 [DatabaseIdentifier:11692715] ENSEMBL:ENST00000529639 [DatabaseIdentifier:11692716] ENSEMBL:ENST00000527548 [DatabaseIdentifier:11692717] ENSEMBL:ENST00000531743 [DatabaseIdentifier:11787718] GeneCards:FAU [DatabaseIdentifier:11840792] HPA:ENSG00000149806-FAU [DatabaseIdentifier:12125334] OpenTargets:ENSG00000149806 [DatabaseIdentifier:12148659] PDB:8JDJ [DatabaseIdentifier:12148669] PDB:6OLE [DatabaseIdentifier:12148666] PDB:8PPK [DatabaseIdentifier:12148662] PDB:6OM0 [DatabaseIdentifier:12148657] PDB:8JDL [DatabaseIdentifier:12148670] PDB:8XXN [DatabaseIdentifier:12148664] PDB:8UJJ [DatabaseIdentifier:12148658] PDB:8JDM [DatabaseIdentifier:12148661] PDB:8UJK [DatabaseIdentifier:12148665] PDB:8G5Y [DatabaseIdentifier:12148668] PDB:9B0W [DatabaseIdentifier:12148660] PDB:8JDK [DatabaseIdentifier:12148663] PDB:9C3H [DatabaseIdentifier:12148667] PDB:6OLF [DatabaseIdentifier:12148692] PDB:8XP2 [DatabaseIdentifier:12148673] PDB:8PPL [DatabaseIdentifier:12148687] PDB:9B11 [DatabaseIdentifier:12148703] PDB:8UKB [DatabaseIdentifier:12146422] PDB:6ZMO [DatabaseIdentifier:12148767] PDB:6ZOJ [DatabaseIdentifier:12148676] PDB:8UJB [DatabaseIdentifier:12148749] PDB:8IFD
databaseName	UniProt
dbId	72370
description	recommendedName: fullName evidence="10"Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein alternativeName: fullName evidence="12"FAU ubiquitin like and ribosomal protein S30 fusion component recommendedName: Ubiquitin-like protein FUBI /component component recommendedName: fullName evidence="9"Small ribosomal subunit protein eS30 alternativeName: 40S ribosomal protein S30 /component
displayName	UniProt:P62861 FAU
geneName	FAU
identifier	P62861
isSequenceChanged	false
keyword	3D-structure Cytoplasm Direct protein sequencing Nucleus Proteomics identification Reference proteome Ribonucleoprotein Ribosomal protein
modified	[InstanceEdit:9926675] Weiser, Joel, 2024-11-03
moleculeType	Protein
name	FAU
otherIdentifier	11718595_a_at 11753927_x_at 16740326 18671377 18671378 18671379 18671380 18671381 18671382 18671383 18671384 18671385 18671386 18671387 200019_PM_s_at 200019_s_at 2197 31955_at 3377464 3377465 3377466 3377467 3377468 3377469 3377470 3377471 3377472 3377473 3813355 7893603 7894699 7894758 7896431 7896621 7949377 A_23_P127438 A_32_P11471 GE86295 GO:0002181 GO:0002227 GO:0002376 GO:0003723 GO:0003735 GO:0005198 GO:0005515 GO:0005615 GO:0005634 GO:0005654 GO:0005737 GO:0005829 GO:0005840 GO:0006412 GO:0015935 GO:0016567 GO:0019731 GO:0019941 GO:0022626 GO:0022627 GO:0031386 GO:0031625 GO:0050830 GO:0061844 GO:0098542 GO:1990904 HMNXSV003049932 ILMN_1664614 TC11001928.hg g4503658_3p_a_at
physicalEntity	[EntityWithAccessionedSequence:R-HSA-72371] FAU [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-6798717] FAU [nucleoplasm] - Homo sapiens
referenceDatabase	[ReferenceDatabase:2] UniProt
referenceGene	[ReferenceDNASequence:ensembl:ENSG00000149806] ENSEMBL:ENSG00000149806 FAU [ReferenceDNASequence:12686827] UCSC:P62861 FAU [ReferenceDNASequence:11337480] BioGPS Gene:2197 FAU [ReferenceDNASequence:11392662] COSMIC - genes:FAU FAU [ReferenceDNASequence:11413634] CTD Gene:2197 FAU [ReferenceDNASequence:11428497] dbSNP Gene:2197 FAU [ReferenceDNASequence:11819364] HGNC:3597 FAU [ReferenceDNASequence:11878483] KEGG:hsa:2197 FAU [ReferenceDNASequence:11967269] Monarch:2197 FAU [ReferenceDNASequence:12051362] NCBI Gene:2197 FAU [ReferenceDNASequence:12110653] OMIM:134690 FAU
schemaClass	ReferenceGeneProduct
secondaryIdentifier	RS30_HUMAN P35544 Q05472 Q95261 Q9H5V4
sequenceLength	133
species	[Species:48887] Homo sapiens
stId	uniprot:P62861
url	http://purl.uniprot.org/uniprot/P62861

Referrals

(referenceEntity)	[EntityWithAccessionedSequence:R-HSA-72371] FAU [cytosol] [EntityWithAccessionedSequence:R-HSA-6798717] FAU [nucleoplasm]
(interactor)	[UndirectedInteraction:11138263] UniProt:P63244 <-> UniProt:P62861 (IntAct) [UndirectedInteraction:11218911] UniProt:P10636-8 <-> UniProt:P62861 (IntAct) [UndirectedInteraction:11283211] UniProt:P06748 <-> UniProt:P62861 (IntAct)

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