Reactome | UniProt:P62701 RPS4X

Schema > ReferenceGeneProduct > Entries

UniProt:P62701 RPS4X Show undefined attributes

chain	initiator methionine:1 chain:2-263
checksum	87200E545A8958B0
comment	FUNCTION Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797).SUBUNIT Component of the small ribosomal subunit (PubMed:23636399). Part of the small subunit (SSU) processome, composed of more than 70 proteins and the RNA chaperone small nucleolar RNA (snoRNA) U3 (PubMed:34516797). Identified in a IGF2BP1-dependent mRNP granule complex containing untranslated mRNAs (PubMed:17289661).INTERACTION Localized in cytoplasmic mRNP granules containing untranslated mRNAs.SIMILARITY Belongs to the eukaryotic ribosomal protein eS4 family.
crossReference	[DatabaseIdentifier:12153090] PDB:7WTS [DatabaseIdentifier:12373271] RefSeq:NP_000998.1 [DatabaseIdentifier:12286952] Pharos - Targets:P62701 [DatabaseIdentifier:12267228] PRO:P62701 [DatabaseIdentifier:12146421] PDB:6ZMI [DatabaseIdentifier:12148766] PDB:6Z6N [DatabaseIdentifier:12148767] PDB:6ZOJ [DatabaseIdentifier:12148786] PDB:6Y57 [DatabaseIdentifier:12146422] PDB:6ZMO [DatabaseIdentifier:12148779] PDB:6ZXH [DatabaseIdentifier:12148785] PDB:8YOO [DatabaseIdentifier:12148774] PDB:6ZXD [DatabaseIdentifier:12148772] PDB:7R4X [DatabaseIdentifier:12148756] PDB:7WTZ [DatabaseIdentifier:12148758] PDB:6ZV6 [DatabaseIdentifier:12148768] PDB:8QOI [DatabaseIdentifier:12148760] PDB:7WTX [DatabaseIdentifier:12148783] PDB:9G8M [DatabaseIdentifier:12148751] PDB:6ZMW [DatabaseIdentifier:12148769] PDB:7K5I [DatabaseIdentifier:12148787] PDB:9G8O [DatabaseIdentifier:12148747] PDB:6ZMT [DatabaseIdentifier:12148762] PDB:6G18 [DatabaseIdentifier:12148745] PDB:7XNX [DatabaseIdentifier:12148749] PDB:8IFD [DatabaseIdentifier:12148750] PDB:7XNY [DatabaseIdentifier:12148790] PDB:6IP8 [DatabaseIdentifier:12148746] PDB:5VYC [DatabaseIdentifier:12148757] PDB:8XSY [DatabaseIdentifier:12148789] PDB:6IP5 [DatabaseIdentifier:12148776] PDB:6ZXG [DatabaseIdentifier:12140101] PDB:7MQA [DatabaseIdentifier:12148759] PDB:8XSZ [DatabaseIdentifier:12148775] PDB:8GLP [DatabaseIdentifier:12148793] PDB:9B0F [DatabaseIdentifier:12148764] PDB:6Z6M [DatabaseIdentifier:12148770] PDB:8K2C [DatabaseIdentifier:12148752] PDB:7WTV [DatabaseIdentifier:12148755] PDB:7WTU [DatabaseIdentifier:12148761] PDB:8XSX [DatabaseIdentifier:12148773] PDB:6ZXE [DatabaseIdentifier:12156081] PDB:6ZOK [DatabaseIdentifier:12148763] PDB:8T4S [DatabaseIdentifier:12148784] PDB:6ZON [DatabaseIdentifier:12148753] PDB:7WTW [DatabaseIdentifier:12148748] PDB:6ZN5 [DatabaseIdentifier:12148788] PDB:6IP6 [DatabaseIdentifier:12148754] PDB:7WTT [DatabaseIdentifier:12148778] PDB:6ZXF [DatabaseIdentifier:12148765] PDB:6Z6L [DatabaseIdentifier:12148780] PDB:6ZP4 [DatabaseIdentifier:12148792] PDB:8UIK [DatabaseIdentifier:12148771] PDB:7TQL [DatabaseIdentifier:12148782] PDB:8YOP [DatabaseIdentifier:12148742] PDB:6ZVJ [DatabaseIdentifier:12148673] PDB:8PPL [DatabaseIdentifier:12148665] PDB:8G5Y [DatabaseIdentifier:12148722] PDB:8PJ5 [DatabaseIdentifier:12156080] PDB:6FEC [DatabaseIdentifier:12148735] PDB:9BLN [DatabaseIdentifier:12148723] PDB:8PJ2 [DatabaseIdentifier:12148696] PDB:9B0H [DatabaseIdentifier:12148684] PDB:8G60 [DatabaseIdentifier:12148669] PDB:6OLE [DatabaseIdentifier:12148677] PDB:8XXM [DatabaseIdentifier:12148704] PDB:4UG0 [DatabaseIdentifier:12148710] PDB:8ZDB [DatabaseIdentifier:12148930] PDB:7QVP [DatabaseIdentifier:12148690] PDB:9B0S [DatabaseIdentifier:12148664] PDB:8UJJ [DatabaseIdentifier:12148683] PDB:9B0O [DatabaseIdentifier:12148738] PDB:8OZ0 [DatabaseIdentifier:12154015] PDB:6YBW [DatabaseIdentifier:12140947] PDB:7MQ8 [DatabaseIdentifier:12148733] PDB:6XA1 [DatabaseIdentifier:12148681] PDB:5A2Q [DatabaseIdentifier:12148682] PDB:8Y0W [DatabaseIdentifier:12148698] PDB:9B0N [DatabaseIdentifier:12148658] PDB:8JDM [DatabaseIdentifier:12148726] PDB:6G5H [DatabaseIdentifier:12148661] PDB:8UJK [DatabaseIdentifier:12148699] PDB:6Y0G [DatabaseIdentifier:12148680] PDB:9B0R [DatabaseIdentifier:12148714] PDB:5LKS [DatabaseIdentifier:12148707] PDB:8ZDD [DatabaseIdentifier:12148739] PDB:7QP6 [DatabaseIdentifier:12148701] PDB:6G4S [DatabaseIdentifier:12148744] PDB:8IFE [DatabaseIdentifier:12148666] PDB:8PPK [DatabaseIdentifier:12148657] PDB:8JDL [DatabaseIdentifier:12148668] PDB:9B0W [DatabaseIdentifier:12148691] PDB:8UIY [DatabaseIdentifier:12148688] PDB:8UIZ [DatabaseIdentifier:12148689] PDB:8UJ9 [DatabaseIdentifier:12148720] PDB:8PJ4 [DatabaseIdentifier:12148674] PDB:8XXL [DatabaseIdentifier:12148685] PDB:8Y0X [DatabaseIdentifier:12148708] PDB:8G6J [DatabaseIdentifier:12148730] PDB:6ZME [DatabaseIdentifier:12148743] PDB:9ED0 [DatabaseIdentifier:12140946] PDB:7MQ9 [DatabaseIdentifier:12148725] PDB:6G5I [DatabaseIdentifier:12148719] PDB:5OA3 [DatabaseIdentifier:12148659] PDB:8JDJ [DatabaseIdentifier:12148721] PDB:9BKD [DatabaseIdentifier:12148679] PDB:9B0Q [DatabaseIdentifier:12148724] PDB:8PJ3 [DatabaseIdentifier:12148741] PDB:9AZS [DatabaseIdentifier:12146423] PDB:6ZVH [DatabaseIdentifier:12148670] PDB:8XXN [DatabaseIdentifier:12148732] PDB:7A09 [DatabaseIdentifier:12148676] PDB:8UJB [DatabaseIdentifier:12148660] PDB:8JDK [DatabaseIdentifier:12148700] PDB:8PJ1 [DatabaseIdentifier:12148716] PDB:6QZP [DatabaseIdentifier:12148675] PDB:6OLI [DatabaseIdentifier:12148715] PDB:9AZN [DatabaseIdentifier:12148692] PDB:8XP2 [DatabaseIdentifier:12148687] PDB:9B11 [DatabaseIdentifier:12148737] PDB:6ZM7 [DatabaseIdentifier:12148663] PDB:9C3H [DatabaseIdentifier:12148697] PDB:4V6X [DatabaseIdentifier:12148709] PDB:6OM7 [DatabaseIdentifier:12148728] PDB:7WU0 [DatabaseIdentifier:12148727] PDB:8PJ6 [DatabaseIdentifier:12148678] PDB:8G61 [DatabaseIdentifier:12148711] PDB:8ZDC [DatabaseIdentifier:11474489] ENSEMBL:ENSG00000198034 [DatabaseIdentifier:11573252] ENSEMBL:ENSP00000362744 [DatabaseIdentifier:11695951] ENSEMBL:ENST00000316084 [DatabaseIdentifier:11789078] GeneCards:RPS4X [DatabaseIdentifier:11804709] GlyGen:P62701 [DatabaseIdentifier:11842103] HPA:ENSG00000198034-RPS4X [DatabaseIdentifier:12126698] OpenTargets:ENSG00000198034 [DatabaseIdentifier:12148731] PDB:6ZUO [DatabaseIdentifier:12148705] PDB:6G51 [DatabaseIdentifier:12148718] PDB:9AZC [DatabaseIdentifier:12148667] PDB:6OLF [DatabaseIdentifier:12148695] PDB:9B0G [DatabaseIdentifier:12148694] PDB:9B0J [DatabaseIdentifier:12148717] PDB:5T2C [DatabaseIdentifier:12148706] PDB:6G53 [DatabaseIdentifier:12148740] PDB:7QP7 [DatabaseIdentifier:12148686] PDB:9B0P [DatabaseIdentifier:12148693] PDB:8XP3 [DatabaseIdentifier:12148702] PDB:6G4W [DatabaseIdentifier:12148729] PDB:6Y2L [DatabaseIdentifier:12148662] PDB:6OM0 [DatabaseIdentifier:12148736] PDB:6ZLW [DatabaseIdentifier:12148703] PDB:8UKB
databaseName	UniProt
dbId	72374
description	recommendedName: fullName evidence="6"Small ribosomal subunit protein eS4, X isoform alternativeName: 40S ribosomal protein S4 alternativeName: SCR10 alternativeName: Single copy abundant mRNA protein
displayName	UniProt:P62701 RPS4X
geneName	RPS4X CCG2 RPS4 SCAR
identifier	P62701
isSequenceChanged	false
keyword	3D-structure Acetylation Cytoplasm Direct protein sequencing Isopeptide bond Nucleus Proteomics identification Reference proteome Ribonucleoprotein Ribosomal protein RNA-binding rRNA-binding Ubl conjugation
modified	[InstanceEdit:9963647] Weiser, Joel, 2025-08-15
moleculeType	Protein
name	RPS4X
otherIdentifier	11757780_x_at 11761933_at 17112005 200933_3p_x_at 200933_PM_x_at 200933_x_at 213347_3p_x_at 213347_PM_x_at 213347_x_at 2806954 3373987 3373989 34643_at 3467630 4012155 4012157 4012158 4012159 4012160 4012161 4012162 4012163 4012164 4012165 4012166 4012167 4012168 4012169 4012170 4012171 4012172 4012173 6191 8173513 A_23_P125519 A_33_P3345414 GO:0002181 GO:0003723 GO:0003735 GO:0005198 GO:0005515 GO:0005634 GO:0005654 GO:0005730 GO:0005737 GO:0005829 GO:0005840 GO:0005925 GO:0006412 GO:0008284 GO:0015935 GO:0016020 GO:0019843 GO:0022626 GO:0022627 GO:0032040 GO:0036464 GO:0042274 GO:0043226 GO:0045727 GO:0070062 GO:1990904 HMNXSV003023235 HMNXSV003044761 Hs.108124.5.A1_3p_a_at Hs.108124.5.A1_3p_x_at ILMN_1810577 ILMN_2166831 PH_hs_0030329 TC0X001138.hg g4506724_3p_a_at
physicalEntity	[EntityWithAccessionedSequence:R-HSA-72375] RPS4X [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-6798713] RPS4X [nucleoplasm] - Homo sapiens
referenceDatabase	[ReferenceDatabase:2] UniProt
referenceGene	[ReferenceDNASequence:ensembl:ENSG00000198034] ENSEMBL:ENSG00000198034 RPS4X [ReferenceDNASequence:12688213] UCSC:P62701 RPS4X [ReferenceDNASequence:11339739] BioGPS Gene:6191 RPS4X [ReferenceDNASequence:11392833] COSMIC - genes:RPS4X RPS4X [ReferenceDNASequence:11415609] CTD Gene:6191 RPS4X [ReferenceDNASequence:11428722] dbSNP Gene:6191 RPS4X [ReferenceDNASequence:11820730] HGNC:10424 RPS4X [ReferenceDNASequence:11880575] KEGG:hsa:6191 RPS4X [ReferenceDNASequence:11969528] Monarch:6191 RPS4X [ReferenceDNASequence:12053621] NCBI Gene:6191 RPS4X [ReferenceDNASequence:12111664] OMIM:312760 RPS4X
schemaClass	ReferenceGeneProduct
secondaryIdentifier	RS4X_HUMAN P12631 P12750 P27576 P55831 Q14727 Q6IPY4
sequenceLength	263
species	[Species:48887] Homo sapiens
stId	uniprot:P62701
url	http://purl.uniprot.org/uniprot/P62701

Referrals

(referenceEntity)

(interactor)

Cite Us!