Reactome | UniProt:P62280 RPS11

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UniProt:P62280 RPS11 Show undefined attributes

chain	initiator methionine:1 chain:2-158
checksum	9FB75DC1D99614B0
comment	FUNCTION Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797).SUBUNIT Component of the small ribosomal subunit. Part of the small subunit (SSU) processome, composed of more than 70 proteins and the RNA chaperone small nucleolar RNA (snoRNA) U3 (PubMed:34516797).INTERACTION Citrullinated by PADI4.SIMILARITY Belongs to the universal ribosomal protein uS17 family.
crossReference	[DatabaseIdentifier:11472005] ENSEMBL:ENSG00000142534 [DatabaseIdentifier:12367514] RefSeq:NP_001006.1 [DatabaseIdentifier:12285422] Pharos - Targets:P62280 [DatabaseIdentifier:12264529] PRO:P62280 [DatabaseIdentifier:12148765] PDB:6Z6L [DatabaseIdentifier:12148747] PDB:6ZMT [DatabaseIdentifier:12148751] PDB:6ZMW [DatabaseIdentifier:12148779] PDB:6ZXH [DatabaseIdentifier:12148788] PDB:6IP6 [DatabaseIdentifier:12140946] PDB:7MQ9 [DatabaseIdentifier:12148722] PDB:8PJ5 [DatabaseIdentifier:12148754] PDB:7WTT [DatabaseIdentifier:12148728] PDB:7WU0 [DatabaseIdentifier:12148719] PDB:5OA3 [DatabaseIdentifier:12140947] PDB:7MQ8 [DatabaseIdentifier:12148783] PDB:9G8M [DatabaseIdentifier:12148753] PDB:7WTW [DatabaseIdentifier:12148738] PDB:8OZ0 [DatabaseIdentifier:12148775] PDB:8GLP [DatabaseIdentifier:12148723] PDB:8PJ2 [DatabaseIdentifier:12148782] PDB:8YOP [DatabaseIdentifier:12148744] PDB:8IFE [DatabaseIdentifier:12148721] PDB:9BKD [DatabaseIdentifier:12148767] PDB:6ZOJ [DatabaseIdentifier:12146421] PDB:6ZMI [DatabaseIdentifier:12148752] PDB:7WTV [DatabaseIdentifier:12148763] PDB:8T4S [DatabaseIdentifier:12148768] PDB:8QOI [DatabaseIdentifier:12148787] PDB:9G8O [DatabaseIdentifier:12148757] PDB:8XSY [DatabaseIdentifier:12148755] PDB:7WTU [DatabaseIdentifier:12148793] PDB:9B0F [DatabaseIdentifier:12148740] PDB:7QP7 [DatabaseIdentifier:12148730] PDB:6ZME [DatabaseIdentifier:12148771] PDB:7TQL [DatabaseIdentifier:12148769] PDB:7K5I [DatabaseIdentifier:12146422] PDB:6ZMO [DatabaseIdentifier:12148745] PDB:7XNX [DatabaseIdentifier:12148742] PDB:6ZVJ [DatabaseIdentifier:12148758] PDB:6ZV6 [DatabaseIdentifier:12148762] PDB:6G18 [DatabaseIdentifier:12148725] PDB:6G5I [DatabaseIdentifier:12156080] PDB:6FEC [DatabaseIdentifier:12148761] PDB:8XSX [DatabaseIdentifier:12148732] PDB:7A09 [DatabaseIdentifier:12148749] PDB:8IFD [DatabaseIdentifier:12148756] PDB:7WTZ [DatabaseIdentifier:12148784] PDB:6ZON [DatabaseIdentifier:12148776] PDB:6ZXG [DatabaseIdentifier:12148739] PDB:7QP6 [DatabaseIdentifier:12148774] PDB:6ZXD [DatabaseIdentifier:12153090] PDB:7WTS [DatabaseIdentifier:12156081] PDB:6ZOK [DatabaseIdentifier:12148780] PDB:6ZP4 [DatabaseIdentifier:12148766] PDB:6Z6N [DatabaseIdentifier:12148724] PDB:8PJ3 [DatabaseIdentifier:12148764] PDB:6Z6M [DatabaseIdentifier:12148735] PDB:9BLN [DatabaseIdentifier:12148731] PDB:6ZUO [DatabaseIdentifier:12148720] PDB:8PJ4 [DatabaseIdentifier:12148786] PDB:6Y57 [DatabaseIdentifier:12148759] PDB:8XSZ [DatabaseIdentifier:12148743] PDB:9ED0 [DatabaseIdentifier:12148737] PDB:6ZM7 [DatabaseIdentifier:12148748] PDB:6ZN5 [DatabaseIdentifier:12148790] PDB:6IP8 [DatabaseIdentifier:12148746] PDB:5VYC [DatabaseIdentifier:12148726] PDB:6G5H [DatabaseIdentifier:12148778] PDB:6ZXF [DatabaseIdentifier:12148792] PDB:8UIK [DatabaseIdentifier:12148750] PDB:7XNY [DatabaseIdentifier:12148770] PDB:8K2C [DatabaseIdentifier:12148729] PDB:6Y2L [DatabaseIdentifier:12148773] PDB:6ZXE [DatabaseIdentifier:12148741] PDB:9AZS [DatabaseIdentifier:12148777] PDB:5AJ0 [DatabaseIdentifier:12154015] PDB:6YBW [DatabaseIdentifier:12148760] PDB:7WTX [DatabaseIdentifier:12140101] PDB:7MQA [DatabaseIdentifier:12148733] PDB:6XA1 [DatabaseIdentifier:12148736] PDB:6ZLW [DatabaseIdentifier:12148785] PDB:8YOO [DatabaseIdentifier:12146423] PDB:6ZVH [DatabaseIdentifier:12148789] PDB:6IP5 [DatabaseIdentifier:12148791] PDB:5FLX [DatabaseIdentifier:12148772] PDB:7R4X [DatabaseIdentifier:12148727] PDB:8PJ6 [DatabaseIdentifier:12148696] PDB:9B0H [DatabaseIdentifier:12148708] PDB:8G6J [DatabaseIdentifier:12148659] PDB:8JDJ [DatabaseIdentifier:12148657] PDB:8JDL [DatabaseIdentifier:12148684] PDB:8G60 [DatabaseIdentifier:12148702] PDB:6G4W [DatabaseIdentifier:12148665] PDB:8G5Y [DatabaseIdentifier:12148663] PDB:9C3H [DatabaseIdentifier:12148689] PDB:8UJ9 [DatabaseIdentifier:12148691] PDB:8UIY [DatabaseIdentifier:12148675] PDB:6OLI [DatabaseIdentifier:12148664] PDB:8UJJ [DatabaseIdentifier:12148662] PDB:6OM0 [DatabaseIdentifier:12148711] PDB:8ZDC [DatabaseIdentifier:12148701] PDB:6G4S [DatabaseIdentifier:12148695] PDB:9B0G [DatabaseIdentifier:12148671] PDB:6OLG [DatabaseIdentifier:12148715] PDB:9AZN [DatabaseIdentifier:12148680] PDB:9B0R [DatabaseIdentifier:12148704] PDB:4UG0 [DatabaseIdentifier:12148685] PDB:8Y0X [DatabaseIdentifier:12148718] PDB:9AZC [DatabaseIdentifier:12148714] PDB:5LKS [DatabaseIdentifier:12148712] PDB:6OLZ [DatabaseIdentifier:12148661] PDB:8UJK [DatabaseIdentifier:12148679] PDB:9B0Q [DatabaseIdentifier:12148706] PDB:6G53 [DatabaseIdentifier:12148686] PDB:9B0P [DatabaseIdentifier:12148666] PDB:8PPK [DatabaseIdentifier:12148670] PDB:8XXN [DatabaseIdentifier:12148658] PDB:8JDM [DatabaseIdentifier:12148673] PDB:8PPL [DatabaseIdentifier:12148693] PDB:8XP3 [DatabaseIdentifier:12148667] PDB:6OLF [DatabaseIdentifier:12148660] PDB:8JDK [DatabaseIdentifier:12148668] PDB:9B0W [DatabaseIdentifier:12148710] PDB:8ZDB [DatabaseIdentifier:12148688] PDB:8UIZ [DatabaseIdentifier:12148687] PDB:9B11 [DatabaseIdentifier:12148682] PDB:8Y0W [DatabaseIdentifier:12148694] PDB:9B0J [DatabaseIdentifier:12148716] PDB:6QZP [DatabaseIdentifier:12148707] PDB:8ZDD [DatabaseIdentifier:12148698] PDB:9B0N [DatabaseIdentifier:12148690] PDB:9B0S [DatabaseIdentifier:12148683] PDB:9B0O [DatabaseIdentifier:12148692] PDB:8XP2 [DatabaseIdentifier:12148674] PDB:8XXL [DatabaseIdentifier:12148678] PDB:8G61 [DatabaseIdentifier:12148700] PDB:8PJ1 [DatabaseIdentifier:12148717] PDB:5T2C [DatabaseIdentifier:12148676] PDB:8UJB [DatabaseIdentifier:12148681] PDB:5A2Q [DatabaseIdentifier:12148703] PDB:8UKB [DatabaseIdentifier:12148677] PDB:8XXM [DatabaseIdentifier:12148709] PDB:6OM7 [DatabaseIdentifier:12148669] PDB:6OLE [DatabaseIdentifier:12148705] PDB:6G51 [DatabaseIdentifier:12148699] PDB:6Y0G [DatabaseIdentifier:12148697] PDB:4V6X [DatabaseIdentifier:12125114] OpenTargets:ENSG00000142534 [DatabaseIdentifier:11840573] HPA:ENSG00000142534-RPS11 [DatabaseIdentifier:11802942] GlyGen:P62280 [DatabaseIdentifier:11787502] GeneCards:RPS11 [DatabaseIdentifier:11692130] ENSEMBL:ENST00000270625 [DatabaseIdentifier:11569431] ENSEMBL:ENSP00000270625
databaseName	UniProt
dbId	72326
description	recommendedName: fullName evidence="6"Small ribosomal subunit protein uS17 alternativeName: 40S ribosomal protein S11
displayName	UniProt:P62280 RPS11
geneName	RPS11
identifier	P62280
isSequenceChanged	false
keyword	3D-structure Acetylation Citrullination Cytoplasm Direct protein sequencing Lipoprotein Methylation Nucleus Palmitate Phosphoprotein Proteomics identification Reference proteome Ribonucleoprotein Ribosomal protein RNA-binding rRNA-binding
modified	[InstanceEdit:9963647] Weiser, Joel, 2025-08-15
moleculeType	Protein
name	RPS11
otherIdentifier	11715376_a_at 11745362_x_at 16654595 16654597 16654599 16654601 16654603 16654605 16654607 16654609 16864159 16864165 18671237 18671238 18671239 18671240 18671241 18671242 200031_PM_s_at 200031_s_at 32330_at 3439259 3439262 3439263 3838606 3838608 3838609 3838610 3838611 3838612 3838613 3838614 3838615 3838616 3838617 3838619 3838620 6205 7893727 7893956 7894634 7894999 7895762 8030368 A_14_P124688 A_21_P0000227 A_23_P101532 GE78949 GO:0002181 GO:0003723 GO:0003735 GO:0005198 GO:0005515 GO:0005634 GO:0005654 GO:0005730 GO:0005737 GO:0005829 GO:0005840 GO:0005925 GO:0006412 GO:0016020 GO:0019843 GO:0022626 GO:0022627 GO:0032040 GO:0042274 GO:0045202 GO:0070062 GO:1990904 HMNXSV003023770 HMNXSV003049920 ILMN_1694367 ILMN_1740587 PH_hs_0030181 RNA33600\|snoRNA_scaRNA_196_88 TC19000735.hg TC19000736.hg X06617_at g4506680_3p_a_at
physicalEntity	[EntityWithAccessionedSequence:R-HSA-72327] RPS11 [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-6791212] RPS11 [nucleoplasm] - Homo sapiens
referenceDatabase	[ReferenceDatabase:2] UniProt
referenceGene	[ReferenceDNASequence:ensembl:ENSG00000142534] ENSEMBL:ENSG00000142534 RPS11 [ReferenceDNASequence:12686532] UCSC:P62280 RPS11 [ReferenceDNASequence:12110458] OMIM:180471 RPS11 [ReferenceDNASequence:12050962] NCBI Gene:6205 RPS11 [ReferenceDNASequence:11966869] Monarch:6205 RPS11 [ReferenceDNASequence:11878120] KEGG:hsa:6205 RPS11 [ReferenceDNASequence:11819143] HGNC:10384 RPS11 [ReferenceDNASequence:11428467] dbSNP Gene:6205 RPS11 [ReferenceDNASequence:11413265] CTD Gene:6205 RPS11 [ReferenceDNASequence:11392632] COSMIC - genes:RPS11 RPS11 [ReferenceDNASequence:11337080] BioGPS Gene:6205 RPS11
referenceTranscript	[ReferenceRNASequence:12549354] RefSeq:NM_001015.5 RPS11
schemaClass	ReferenceGeneProduct
secondaryIdentifier	RS11_HUMAN B2R4F5 P04643 Q498Y6 Q6IRY0
sequenceLength	158
species	[Species:48887] Homo sapiens
stId	uniprot:P62280
url	http://purl.uniprot.org/uniprot/P62280

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