Reactome | UniProt:P61353 RPL27

Schema > ReferenceGeneProduct > Entries

UniProt:P61353 RPL27 Show undefined attributes

chain	chain:1-136
checksum	73F4151495029A32
comment	FUNCTION Component of the large ribosomal subunit (PubMed:12962325, PubMed:23636399, PubMed:25901680, PubMed:25957688, PubMed:32669547). Required for proper rRNA processing and maturation of 28S and 5.8S rRNAs (PubMed:25424902).SUBUNIT Component of the large ribosomal subunit (PubMed:12962325, PubMed:23636399, PubMed:25901680, PubMed:25957688, PubMed:32669547). Interacts with RRP1B (PubMed:20926688). Interacts with DHX33 (PubMed:26100019).INTERACTION Detected on cytosolic polysomes (PubMed:25957688). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).DISEASE The disease is caused by variants affecting the gene represented in this entry.SIMILARITY Belongs to the eukaryotic ribosomal protein eL27 family.
crossReference	[DatabaseIdentifier:12148680] PDB:9B0R [DatabaseIdentifier:12415965] RefSeq:NP_001336850.1 [DatabaseIdentifier:12415963] RefSeq:NP_001336851.1 [DatabaseIdentifier:12415964] RefSeq:NP_000979.1 [DatabaseIdentifier:12286307] Pharos - Targets:P61353 [DatabaseIdentifier:12246219] PRO:P61353 [DatabaseIdentifier:12145968] PDB:8INE [DatabaseIdentifier:12148765] PDB:6Z6L [DatabaseIdentifier:12148945] PDB:8FL9 [DatabaseIdentifier:12145825] PDB:8INF [DatabaseIdentifier:12148733] PDB:6XA1 [DatabaseIdentifier:12148940] PDB:8OJ8 [DatabaseIdentifier:12139131] PDB:8FL2 [DatabaseIdentifier:12148730] PDB:6ZME [DatabaseIdentifier:12148938] PDB:8QFD [DatabaseIdentifier:12148737] PDB:6ZM7 [DatabaseIdentifier:12148744] PDB:8IFE [DatabaseIdentifier:12148761] PDB:8XSX [DatabaseIdentifier:12148946] PDB:8QYX [DatabaseIdentifier:12145826] PDB:8IDY [DatabaseIdentifier:12144882] PDB:8IPY [DatabaseIdentifier:12148943] PDB:9GY4 [DatabaseIdentifier:12148939] PDB:8OJ5 [DatabaseIdentifier:12148789] PDB:6IP5 [DatabaseIdentifier:12144883] PDB:8IPX [DatabaseIdentifier:12148936] PDB:6W6L [DatabaseIdentifier:12148766] PDB:6Z6N [DatabaseIdentifier:12144887] PDB:8IR1 [DatabaseIdentifier:12148941] PDB:6LSR [DatabaseIdentifier:12148937] PDB:8IDT [DatabaseIdentifier:12148792] PDB:8UIK [DatabaseIdentifier:12148786] PDB:6Y57 [DatabaseIdentifier:12145976] PDB:8FL6 [DatabaseIdentifier:12148764] PDB:6Z6M [DatabaseIdentifier:12146422] PDB:6ZMO [DatabaseIdentifier:12148749] PDB:8IFD [DatabaseIdentifier:12150999] PDB:7OW7 [DatabaseIdentifier:12144892] PDB:8IPD [DatabaseIdentifier:12148782] PDB:8YOP [DatabaseIdentifier:12148777] PDB:5AJ0 [DatabaseIdentifier:12145979] PDB:8FKY [DatabaseIdentifier:12144889] PDB:8INK [DatabaseIdentifier:12148757] PDB:8XSY [DatabaseIdentifier:12148947] PDB:7F5S [DatabaseIdentifier:12148783] PDB:9G8M [DatabaseIdentifier:12139130] PDB:8FL4 [DatabaseIdentifier:12148935] PDB:6LQM [DatabaseIdentifier:12148944] PDB:6LU8 [DatabaseIdentifier:12145978] PDB:8FL7 [DatabaseIdentifier:12148768] PDB:8QOI [DatabaseIdentifier:12148934] PDB:8OJ0 [DatabaseIdentifier:12148790] PDB:6IP8 [DatabaseIdentifier:12148775] PDB:8GLP [DatabaseIdentifier:12139132] PDB:8FL3 [DatabaseIdentifier:12148741] PDB:9AZS [DatabaseIdentifier:12148942] PDB:6LSS [DatabaseIdentifier:12148770] PDB:8K2C [DatabaseIdentifier:12144886] PDB:8IR3 [DatabaseIdentifier:12148759] PDB:8XSZ [DatabaseIdentifier:12148788] PDB:6IP6 [DatabaseIdentifier:12148793] PDB:9B0F [DatabaseIdentifier:12148785] PDB:8YOO [DatabaseIdentifier:12146421] PDB:6ZMI [DatabaseIdentifier:12145980] PDB:8FKZ [DatabaseIdentifier:12144891] PDB:9QIW [DatabaseIdentifier:12148665] PDB:8G5Y [DatabaseIdentifier:12148691] PDB:8UIY [DatabaseIdentifier:12148668] PDB:9B0W [DatabaseIdentifier:12148684] PDB:8G60 [DatabaseIdentifier:12148658] PDB:8JDM [DatabaseIdentifier:12148927] PDB:8FLC [DatabaseIdentifier:12148672] PDB:8G5Z [DatabaseIdentifier:12144890] PDB:8RL2 [DatabaseIdentifier:12148703] PDB:8UKB [DatabaseIdentifier:12148663] PDB:9C3H [DatabaseIdentifier:12148931] PDB:8IE3 [DatabaseIdentifier:12148715] PDB:9AZN [DatabaseIdentifier:12145970] PDB:8FLD [DatabaseIdentifier:12148667] PDB:6OLF [DatabaseIdentifier:12148689] PDB:8UJ9 [DatabaseIdentifier:12148685] PDB:8Y0X [DatabaseIdentifier:12148694] PDB:9B0J [DatabaseIdentifier:12148662] PDB:6OM0 [DatabaseIdentifier:12148683] PDB:9B0O [DatabaseIdentifier:12148708] PDB:8G6J [DatabaseIdentifier:12148679] PDB:9B0Q [DatabaseIdentifier:12145972] PDB:8FLB [DatabaseIdentifier:12148678] PDB:8G61 [DatabaseIdentifier:12148923] PDB:8UJC [DatabaseIdentifier:12148675] PDB:6OLI [DatabaseIdentifier:12148659] PDB:8JDJ [DatabaseIdentifier:12148933] PDB:9GMO [DatabaseIdentifier:12148928] PDB:8A3D [DatabaseIdentifier:12148660] PDB:8JDK [DatabaseIdentifier:12148669] PDB:6OLE [DatabaseIdentifier:12148687] PDB:9B11 [DatabaseIdentifier:12148926] PDB:6Y6X [DatabaseIdentifier:12148925] PDB:8FLF [DatabaseIdentifier:12148729] PDB:6Y2L [DatabaseIdentifier:12148699] PDB:6Y0G [DatabaseIdentifier:12148932] PDB:8OHD [DatabaseIdentifier:12148704] PDB:4UG0 [DatabaseIdentifier:12148698] PDB:9B0N [DatabaseIdentifier:12148716] PDB:6QZP [DatabaseIdentifier:12148688] PDB:8UIZ [DatabaseIdentifier:12148714] PDB:5LKS [DatabaseIdentifier:12148661] PDB:8UJK [DatabaseIdentifier:12148676] PDB:8UJB [DatabaseIdentifier:11493787] ENSEMBL:ENSG00000131469 [DatabaseIdentifier:11601359] ENSEMBL:ENSP00000464813 [DatabaseIdentifier:11601360] ENSEMBL:ENSP00000467587 [DatabaseIdentifier:11601361] ENSEMBL:ENSP00000253788 [DatabaseIdentifier:11724060] ENSEMBL:ENST00000253788 [DatabaseIdentifier:11724058] ENSEMBL:ENST00000589913 [DatabaseIdentifier:11724059] ENSEMBL:ENST00000589037 [DatabaseIdentifier:11788417] GeneCards:RPL27 [DatabaseIdentifier:11803995] GlyGen:P61353 [DatabaseIdentifier:11841469] HPA:ENSG00000131469-RPL27 [DatabaseIdentifier:12126037] OpenTargets:ENSG00000131469 [DatabaseIdentifier:12137395] Orphanet:RPL27 [DatabaseIdentifier:12148718] PDB:9AZC [DatabaseIdentifier:12148929] PDB:7BHP [DatabaseIdentifier:12148697] PDB:4V6X [DatabaseIdentifier:12148712] PDB:6OLZ [DatabaseIdentifier:12145969] PDB:8FLA [DatabaseIdentifier:12145971] PDB:8FLE [DatabaseIdentifier:12148664] PDB:8UJJ [DatabaseIdentifier:12148671] PDB:6OLG [DatabaseIdentifier:12148924] PDB:8UJD [DatabaseIdentifier:12148686] PDB:9B0P [DatabaseIdentifier:12148682] PDB:8Y0W [DatabaseIdentifier:12148690] PDB:9B0S [DatabaseIdentifier:12148709] PDB:6OM7 [DatabaseIdentifier:12148717] PDB:5T2C [DatabaseIdentifier:12148695] PDB:9B0G [DatabaseIdentifier:12148696] PDB:9B0H [DatabaseIdentifier:12148657] PDB:8JDL
databaseName	UniProt
dbId	72439
description	recommendedName: fullName evidence="9"Large ribosomal subunit protein eL27 alternativeName: 60S ribosomal protein L27
displayName	UniProt:P61353 RPL27
geneName	RPL27
identifier	P61353
isSequenceChanged	false
keyword	3D-structure Acetylation Cytoplasm Diamond-Blackfan anemia Direct protein sequencing Endoplasmic reticulum Proteomics identification Reference proteome Ribonucleoprotein Ribosomal protein
modified	[InstanceEdit:9926675] Weiser, Joel, 2024-11-03
moleculeType	Protein
name	RPL27
otherIdentifier	11718051_a_at 11757328_x_at 16654327 16654329 16654331 16654333 16654335 16654337 16654339 16654341 16654347 16654349 16834540 18671465 18671466 18671467 18671468 200025_PM_s_at 200025_s_at 2485239 3722306 3722307 3722308 3722309 3722310 3722311 3722312 3722316 3722318 3722319 39830_at 6155 7892541 7892986 7893184 7895360 7895656 7896590 8007441 A_23_P141389 GE477345 GO:0002181 GO:0003723 GO:0003735 GO:0005198 GO:0005515 GO:0005634 GO:0005654 GO:0005730 GO:0005737 GO:0005783 GO:0005791 GO:0005829 GO:0005840 GO:0005925 GO:0006364 GO:0006412 GO:0016020 GO:0022625 GO:0022626 GO:0045202 GO:0070062 GO:0098556 GO:1990904 HMNXSV003051979 ILMN_1656807 L19527_at PH_hs_0030041 TC17000544.hg g4506622_3p_a_at
physicalEntity	[EntityWithAccessionedSequence:R-HSA-72440] RPL27 [cytosol] - Homo sapiens
referenceDatabase	[ReferenceDatabase:2] UniProt
referenceGene	[ReferenceDNASequence:ensembl:ENSG00000131469] ENSEMBL:ENSG00000131469 RPL27 [ReferenceDNASequence:12752193] UCSC:P61353 RPL27 [ReferenceDNASequence:11359441] BioGPS Gene:6155 RPL27 [ReferenceDNASequence:11401735] COSMIC - genes:RPL27 RPL27 [ReferenceDNASequence:11414675] CTD Gene:6155 RPL27 [ReferenceDNASequence:11439109] dbSNP Gene:6155 RPL27 [ReferenceDNASequence:11820069] HGNC:10328 RPL27 [ReferenceDNASequence:11898568] KEGG:hsa:6155 RPL27 [ReferenceDNASequence:11989230] Monarch:6155 RPL27 [ReferenceDNASequence:12073323] NCBI Gene:6155 RPL27 [ReferenceDNASequence:12111186] OMIM:607526 RPL27
referenceTranscript	[ReferenceRNASequence:12597654] RefSeq:NM_001349921.2 RPL27 [ReferenceRNASequence:12597653] RefSeq:NM_001349922.2 RPL27 [ReferenceRNASequence:12597655] RefSeq:NM_000988.5 RPL27
schemaClass	ReferenceGeneProduct
secondaryIdentifier	RL27_HUMAN P08526 Q4G0A9
sequenceLength	136
species	[Species:48887] Homo sapiens
stId	uniprot:P61353
url	http://purl.uniprot.org/uniprot/P61353

Referrals

(referenceEntity)

[EntityWithAccessionedSequence:R-HSA-72440] RPL27 [cytosol]

(interactor)

Cite Us!