Reactome | UniProt:P56182 RRP1

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UniProt:P56182 RRP1 Show undefined attributes

chain	chain:1-461
checksum	C6F204EF4161AEAE
comment	FUNCTION Plays a critical role in the generation of 28S rRNA.SUBUNIT Interacts with C1QBP (PubMed:21536856). Interacts with RRP1B (PubMed:20926688).INTERACTION Ubiquitously expressed in fetal and adult tissues.PTM Methylated at Gln-427 by N6AMT1.SIMILARITY Belongs to the RRP1 family.
crossReference	[DatabaseIdentifier:12423328] RefSeq:NP_003674.1 [DatabaseIdentifier:12288698] Pharos - Targets:P56182 [DatabaseIdentifier:12249951] PRO:P56182 [DatabaseIdentifier:12145981] PDB:8FKP [DatabaseIdentifier:12145985] PDB:8FKR [DatabaseIdentifier:12145983] PDB:8FKT [DatabaseIdentifier:12145977] PDB:8FKV [DatabaseIdentifier:12128477] OpenTargets:ENSG00000160214 [DatabaseIdentifier:11843861] HPA:ENSG00000160214-RRP1 [DatabaseIdentifier:11806793] GlyGen:P56182 [DatabaseIdentifier:11790857] GeneCards:RRP1 [DatabaseIdentifier:11729115] ENSEMBL:ENST00000497547 [DatabaseIdentifier:11606416] ENSEMBL:ENSP00000417464 [DatabaseIdentifier:11497531] ENSEMBL:ENSG00000160214
databaseName	UniProt
dbId	60317
description	recommendedName: Ribosomal RNA processing protein 1 homolog A alternativeName: Novel nuclear protein 1 shortName: NNP-1 alternativeName: Nucleolar protein Nop52 alternativeName: RRP1-like protein
displayName	UniProt:P56182 RRP1
geneName	RRP1 D21S2056E NNP1 NOP52 RRP1A
identifier	P56182
isSequenceChanged	false
keyword	3D-structure Methylation Nucleus Phosphoprotein Proteomics identification Reference proteome rRNA processing
modified	[InstanceEdit:9926675] Weiser, Joel, 2024-11-03
moleculeType	Protein
name	RRP1
otherIdentifier	11749256_a_at 11756965_a_at 11759286_at 16923397 218758_PM_s_at 218758_s_at 222733_3p_x_at 222733_PM_x_at 222733_x_at 3923316 3923317 3923318 3923319 3923321 3923322 3923323 3923324 3923325 3923326 3923327 3923328 3923329 3923330 3923331 3923333 3923334 3923337 3923339 3923340 3923341 3923342 3923343 56952_at 8068938 8568 A_14_P123837 A_14_P127449 A_23_P80129 A_23_P80136 GE56804 GO:0003723 GO:0005515 GO:0005634 GO:0005694 GO:0005730 GO:0006364 GO:0030688 ILMN_1792960 PH_hs_0006095 TC21000214.hg g12653222_3p_x_at g4503246_3p_a_at
physicalEntity	[EntityWithAccessionedSequence:R-HSA-6792441] RRP1 [nucleoplasm] - Homo sapiens
referenceDatabase	[ReferenceDatabase:2] UniProt
referenceGene	[ReferenceDNASequence:12754639] UCSC:P56182 RRP1 [ReferenceDNASequence:12113237] OMIM:610653 RRP1 [ReferenceDNASequence:12076933] NCBI Gene:8568 RRP1 [ReferenceDNASequence:11992840] Monarch:8568 RRP1 [ReferenceDNASequence:11901845] KEGG:hsa:8568 RRP1 [ReferenceDNASequence:11822520] HGNC:18785 RRP1 [ReferenceDNASequence:11439334] dbSNP Gene:8568 RRP1 [ReferenceDNASequence:11418377] CTD Gene:8568 RRP1 [ReferenceDNASequence:11392265] COSMIC - genes:RRP1 RPLP1 [ReferenceDNASequence:11363051] BioGPS Gene:8568 RRP1 [ReferenceDNASequence:ensembl:ENSG00000160214] ENSEMBL:ENSG00000160214 RRP1
referenceTranscript	[ReferenceRNASequence:12604915] RefSeq:NM_003683.6 RRP1
schemaClass	ReferenceGeneProduct
secondaryIdentifier	RRP1_HUMAN Q9NST5
sequenceLength	461
species	[Species:48887] Homo sapiens
stId	uniprot:P56182
url	http://purl.uniprot.org/uniprot/P56182

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[EntityWithAccessionedSequence:R-HSA-6792441] RRP1 [nucleoplasm]

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