Reactome | UniProt:P54791 ORC4

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UniProt:P54791 ORC4 Show undefined attributes

chain	chain:1-529
checksum	ACF064F2C633F13F
comment	FUNCTION Component of the origin recognition complex (ORC) that binds origins of replication. It has a role in both chromosomal replication and mating type transcriptional silencing. Binds to the ARS consensus sequence (ACS) of origins of replication.SUBUNIT Component of the origin recognition complex (ORC) composed of at least ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6.INTERACTION Present with 2170 molecules/cell in log phase SD medium.SIMILARITY Belongs to the ORC4 family.
crossReference	[DatabaseIdentifier:12439389] RefSeq:NP_015488.1 [DatabaseIdentifier:12258135] PRO:P54791 [DatabaseIdentifier:12142007] PDB:5ZR1 [DatabaseIdentifier:12141993] PDB:8ZP4 [DatabaseIdentifier:12141991] PDB:6WGG [DatabaseIdentifier:12142002] PDB:7TJJ [DatabaseIdentifier:12142001] PDB:7TJI [DatabaseIdentifier:12141989] PDB:7MCA [DatabaseIdentifier:12141995] PDB:8ZP5 [DatabaseIdentifier:12141997] PDB:9GJW [DatabaseIdentifier:12142003] PDB:9GM5 [DatabaseIdentifier:12142004] PDB:9GJP [DatabaseIdentifier:12141998] PDB:7TJF [DatabaseIdentifier:12141990] PDB:5V8F [DatabaseIdentifier:12141996] PDB:7TJH [DatabaseIdentifier:12142006] PDB:6RQC [DatabaseIdentifier:12141999] PDB:6WGC [DatabaseIdentifier:12141987] PDB:8ZPK [DatabaseIdentifier:12141985] PDB:9BCX [DatabaseIdentifier:12141992] PDB:6WGI [DatabaseIdentifier:12142000] PDB:7TJK [DatabaseIdentifier:11739990] ENSEMBL:YPR162C_mRNA [DatabaseIdentifier:11617291] ENSEMBL:YPR162C [DatabaseIdentifier:11504954] ENSEMBL:YPR162C
databaseName	UniProt
dbId	97402
description	recommendedName: Origin recognition complex subunit 4 alternativeName: Origin recognition complex 56 kDa subunit
displayName	UniProt:P54791 ORC4
geneName	ORC4 YPR162C P9325.5
identifier	P54791
isSequenceChanged	false
keyword	3D-structure Direct protein sequencing DNA replication DNA-binding Nucleus Phosphoprotein Reference proteome
modified	[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
moleculeType	Protein
name	ORC4
otherIdentifier	856291 GO:0000808 GO:0003677 GO:0003688 GO:0005515 GO:0005575 GO:0005634 GO:0005654 GO:0005656 GO:0005664 GO:0006260 GO:0006267 GO:0006270 GO:0006325 GO:0008150 GO:0030466 GO:0031261
physicalEntity	[EntityWithAccessionedSequence:R-SCE-9749319] yORC4 [nucleoplasm] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-68519] ORC4 [nucleoplasm] - Saccharomyces cerevisiae
referenceDatabase	[ReferenceDatabase:2] UniProt
referenceGene	[ReferenceDNASequence:12759804] UCSC:P54791 ORC4 [ReferenceDNASequence:12084365] NCBI Gene:856291 ORC4 [ReferenceDNASequence:12000272] Monarch:856291 ORC4 [ReferenceDNASequence:11908607] KEGG:sce:YPR162C ORC4 [ReferenceDNASequence:11370483] BioGPS Gene:856291 ORC4
referenceTranscript	[ReferenceRNASequence:12620900] RefSeq:NM_001184259.1 ORC4
schemaClass	ReferenceGeneProduct
secondaryIdentifier	ORC4_YEAST D6W4G3
sequenceLength	529
species	[Species:68322] Saccharomyces cerevisiae
stId	uniprot:P54791
url	http://purl.uniprot.org/uniprot/P54791

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