UniProt:P49146 NPY2R

chain
  • chain:1-381
checksum 7D018C0169597BC7
comment
  • FUNCTION Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid.INTERACTION High levels in amygdala, corpus callosum, hippocampus and subthalamic nucleus. Also detectable in caudate nucleus, hypothalamus and substantia nigra.SIMILARITY Belongs to the G-protein coupled receptor 1 family.
crossReference
databaseName UniProt
dbId 60666
description
  • recommendedName: Neuropeptide Y receptor type 2 shortName: NPY2-R alternativeName: NPY-Y2 receptor shortName: Y2 receptor
displayName UniProt:P49146 NPY2R
geneName
  • NPY2R
identifier P49146
isSequenceChanged false
keyword
  • 3D-structure
  • Cell membrane
  • Disulfide bond
  • G-protein coupled receptor
  • Glycoprotein
  • Lipoprotein
  • Membrane
  • Palmitate
  • Proteomics identification
  • Receptor
  • Reference proteome
  • Transducer
  • Transmembrane
  • Transmembrane helix
modified [InstanceEdit:9926675] Weiser, Joel, 2024-11-03
moleculeType Protein
name
  • NPY2R
otherIdentifier
  • 11735784_at
  • 11735785_a_at
  • 16971691
  • 210729_PM_at
  • 210729_at
  • 210730_PM_s_at
  • 210730_s_at
  • 2748727
  • 2748728
  • 2748729
  • 2748732
  • 2748733
  • 2748734
  • 2748736
  • 33525_at
  • 4887
  • 8097938
  • A_23_P58169
  • A_33_P3396244
  • GE80127
  • GO:0001601
  • GO:0001662
  • GO:0002793
  • GO:0003151
  • GO:0003214
  • GO:0004930
  • GO:0004983
  • GO:0005246
  • GO:0005515
  • GO:0005886
  • GO:0005929
  • GO:0007165
  • GO:0007186
  • GO:0007193
  • GO:0007204
  • GO:0007218
  • GO:0007263
  • GO:0007626
  • GO:0010811
  • GO:0016020
  • GO:0031645
  • GO:0033603
  • GO:0038023
  • GO:0043226
  • GO:0045987
  • GO:0046010
  • GO:0050805
  • GO:0051048
  • GO:0051967
  • GO:0090394
  • GO:0097730
  • GO:0098772
  • GO:0098793
  • GO:0098978
  • GO:0099538
  • GO:0141162
  • GO:2000252
  • HMNXSV003019454
  • ILMN_1660360
  • PH_hs_0027631
  • TC04000782.hg
  • g1000750_3p_at
  • g1063633_3p_a_at
  • g4505446_3p_s_at
  • g4505446_3p_x_at
physicalEntity
referenceDatabase [ReferenceDatabase:2] UniProt
referenceGene
referenceTranscript
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • NPY2R_HUMAN
  • Q13281
  • Q13457
  • Q4W5G7
  • Q6AZZ6
  • Q9UE67
sequenceLength 381
species [Species:48887] Homo sapiens
stId uniprot:P49146
url http://purl.uniprot.org/uniprot/P49146
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