Reactome | UniProt:P43639 CKB1

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UniProt:P43639 CKB1 Show undefined attributes

chain	initiator methionine:1 chain:2-278
checksum	9ACA8D285E6990AF
comment	FUNCTION Regulatory subunit of casein kinase II/CK2 (By similarity). As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine (By similarity).SUBUNIT Tetramer composed of an alpha subunit, an alpha' subunit, one beta subunit and one beta' subunit (PubMed:12242279). Interacts with FACT subunits POB3 and SPT16 (PubMed:12242279). interacts with YTA7 (PubMed:22156209).INTERACTION Phosphorylated by alpha subunit.MISCELLANEOUS Present with 8120 molecules/cell in log phase SD medium.SIMILARITY Belongs to the casein kinase 2 subunit beta family.
crossReference	[DatabaseIdentifier:12394073] RefSeq:NP_011496.3 [DatabaseIdentifier:12277923] PRO:P43639 [DatabaseIdentifier:11709328] ENSEMBL:YGL019W_mRNA [DatabaseIdentifier:11586629] ENSEMBL:YGL019W [DatabaseIdentifier:11484177] ENSEMBL:YGL019W
databaseName	UniProt
dbId	93714
description	recommendedName: Casein kinase II subunit beta shortName: CK II beta
displayName	UniProt:P43639 CKB1
geneName	CKB1 YGL019W
identifier	P43639
isSequenceChanged	false
keyword	Acetylation Direct protein sequencing Phosphoprotein Reference proteome
modified	[InstanceEdit:9963647] Weiser, Joel, 2025-08-15
moleculeType	Protein
name	CKB1
otherIdentifier	852865 GO:0000028 GO:0003674 GO:0005515 GO:0005575 GO:0005654 GO:0005730 GO:0005737 GO:0005956 GO:0006356 GO:0006359 GO:0006360 GO:0006364 GO:0006468 GO:0006974 GO:0008150 GO:0008270 GO:0009451 GO:0018105 GO:0018107 GO:0018193 GO:0019887 GO:0030234 GO:0030291 GO:0030490 GO:0031167 GO:0032040 GO:0032545 GO:0034456 GO:0035690 GO:0042790 GO:0043167 GO:0051726 GO:0060962
physicalEntity	[EntityWithAccessionedSequence:R-SCE-6790659] CKB1 [nucleoplasm] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-6801319] CKB1 [secretory granule lumen] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-6806508] CKB1 [extracellular region] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-6801290] CKB1 [ficolin-1-rich granule lumen] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-6805067] CKB1 [nucleoplasm] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-201693] CKB1 [cytosol] - Saccharomyces cerevisiae
referenceDatabase	[ReferenceDatabase:2] UniProt
referenceGene	[ReferenceDNASequence:12695234] UCSC:P43639 CKB1 [ReferenceDNASequence:12063430] NCBI Gene:852865 CKB1 [ReferenceDNASequence:11979337] Monarch:852865 CKB1 [ReferenceDNASequence:11889421] KEGG:sce:YGL019W CKB1 [ReferenceDNASequence:11349548] BioGPS Gene:852865 CKB1
referenceTranscript	[ReferenceRNASequence:12575830] RefSeq:NM_001180884.3 CKB1
schemaClass	ReferenceGeneProduct
secondaryIdentifier	CSK2B_YEAST D6VUB8 Q9URG5
sequenceLength	278
species	[Species:68322] Saccharomyces cerevisiae
stId	uniprot:P43639
url	http://purl.uniprot.org/uniprot/P43639

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