UniProt:P35070 BTC

chain
  • signal peptide:1-31
  • chain:32-178
  • chain:32-111
  • propeptide:112-178
checksum 27AC77BD92001F0F
comment
  • FUNCTION Growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells.SUBUNIT Monomer. Interacts with EGFR and ERBB4.INTERACTION Synthesized in several tissues and tumor cells. Predominantly expressed in pancreas and small intestine.
crossReference
databaseName UniProt
dbId 51000
description
  • recommendedName: Probetacellulin component recommendedName: Betacellulin shortName: BTC /component
displayName UniProt:P35070 BTC
geneName
  • BTC
identifier P35070
isSequenceChanged false
keyword
  • 3D-structure
  • Cell membrane
  • Disulfide bond
  • EGF-like domain
  • Glycoprotein
  • Growth factor
  • Membrane
  • Mitogen
  • Proteomics identification
  • Reference proteome
  • Secreted
  • Signal
  • Transmembrane
  • Transmembrane helix
modified [InstanceEdit:9926675] Weiser, Joel, 2024-11-03
moleculeType Protein
name
  • BTC
otherIdentifier
  • 11740532_s_at
  • 11762566_at
  • 16976868
  • 207326_PM_at
  • 207326_at
  • 241412_PM_at
  • 241412_at
  • 2773544
  • 2773546
  • 2773547
  • 2773548
  • 2773549
  • 2773550
  • 2773551
  • 2773554
  • 2773557
  • 2773561
  • 2773562
  • 2773563
  • 2773565
  • 2773566
  • 33975_at
  • 685
  • 8101002
  • 83477_at
  • A_23_P135722
  • A_32_P865613
  • GE768390
  • GO:0003014
  • GO:0005154
  • GO:0005515
  • GO:0005576
  • GO:0005615
  • GO:0005886
  • GO:0006915
  • GO:0007173
  • GO:0008083
  • GO:0008283
  • GO:0008284
  • GO:0016020
  • GO:0030297
  • GO:0030669
  • GO:0035810
  • GO:0038134
  • GO:0038138
  • GO:0045597
  • GO:0045840
  • GO:0048018
  • GO:0048146
  • GO:0051781
  • GO:0098772
  • GO:1904019
  • GO:1904036
  • HMNXSV003022354
  • Hs.154191.0.A1_3p_at
  • ILMN_2081070
  • PH_hs_0004202
  • S55606_at
  • TC04001292.hg
  • g4502460_3p_at
physicalEntity
referenceDatabase [ReferenceDatabase:2] UniProt
referenceGene
referenceTranscript
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • BTC_HUMAN
  • Q96F48
sequenceLength 178
species [Species:48887] Homo sapiens
stId uniprot:P35070
url http://purl.uniprot.org/uniprot/P35070
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