UniProt:P26371 KRTAP5-9

chain
  • chain:1-169
checksum 219B14FEEB49D4AB
comment
  • FUNCTION In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.SUBUNIT Interacts with hair keratins.INTERACTION Restricted to hair root, not detected in any other tissues. Expressed in cuticle layers of differentiating hair follicles.DEVELOPMENTAL STAGE At a late stage of fiber differentiation.SIMILARITY Belongs to the KRTAP type 5 family.
crossReference
databaseName UniProt
dbId 58265
description
  • recommendedName: Keratin-associated protein 5-9 alternativeName: Keratin, cuticle, ultrahigh sulfur 1 alternativeName: Keratin, ultra high-sulfur matrix protein A alternativeName: Keratin-associated protein 5.9 alternativeName: UHS keratin A shortName: UHS KerA alternativeName: Ultrahigh sulfur keratin-associated protein 5.9
displayName UniProt:P26371 KRTAP5-9
geneName
  • KRTAP5-9
  • KAP5.9
  • KRN1
  • KRTAP5.9
  • UHSK1
identifier P26371
isSequenceChanged false
keyword
  • Keratin
  • Proteomics identification
  • Reference proteome
  • Repeat
modified [InstanceEdit:9926675] Weiser, Joel, 2024-11-03
moleculeType Protein
name
  • KRTAP5-9
otherIdentifier
  • 11740533_at
  • 16728509
  • 214517_PM_at
  • 214517_at
  • 3316967
  • 3316971
  • 3316994
  • 3339057
  • 3339058
  • 3339059
  • 3339060
  • 3339061
  • 3339062
  • 3339063
  • 3358923
  • 34555_at
  • 3846
  • 7942261
  • A_14_P136975
  • A_23_P13048
  • A_33_P3271087
  • GE59901
  • GE85721
  • GO:0005515
  • GO:0005829
  • GO:0005882
  • GO:0008544
  • GO:0042802
  • GO:0048856
  • HMNXSV003046655
  • Hs.2743.0.S1_3p_at
  • ILMN_1766565
  • PH_hs_0028713
  • PH_hs_0030890
  • TC11000737.hg
  • X63755_at
  • g10567823_3p_s_at
physicalEntity
referenceDatabase [ReferenceDatabase:2] UniProt
referenceGene
referenceTranscript
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • KRA59_HUMAN
  • Q14564
  • Q3MIP8
sequenceLength 169
species [Species:48887] Homo sapiens
stId uniprot:P26371
url http://purl.uniprot.org/uniprot/P26371

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