UniProt:P25800 LMO1

chain
  • chain:1-156
checksum 6BAFBE1F870CCAAC
comment
  • FUNCTION May be involved in gene regulation within neural lineage cells potentially by direct DNA binding or by binding to other transcription factors.INTERACTION Expressed mainly in the central nervous. Low level of expression in other tissues including thymus.DISEASE A chromosomal aberration involving LMO1 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(11,14)(p15;q11) with TCRD.SEQUENCE CAUTION Extended N-terminus.
crossReference
databaseName UniProt
dbId 63072
description
  • recommendedName: Rhombotin-1 alternativeName: Cysteine-rich protein TTG-1 alternativeName: LIM domain only protein 1 shortName: LMO-1 alternativeName: T-cell translocation protein 1
displayName UniProt:P25800 LMO1
geneName
  • LMO1
  • RBTN1
  • RHOM1
  • TTG1
identifier P25800
isSequenceChanged false
keyword
  • Alternative splicing
  • Chromosomal rearrangement
  • LIM domain
  • Metal-binding
  • Nucleus
  • Proteomics identification
  • Proto-oncogene
  • Reference proteome
  • Repeat
  • Zinc
modified [InstanceEdit:9926675] Weiser, Joel, 2024-11-03
moleculeType Protein
name
  • LMO1
otherIdentifier
  • 11728452_a_at
  • 16735366
  • 206718_PM_at
  • 206718_at
  • 3361686
  • 3361687
  • 3361689
  • 3361690
  • 3361691
  • 3361696
  • 3361726
  • 3361727
  • 3361728
  • 3361729
  • 3361736
  • 3361737
  • 35103_i_at
  • 35104_r_at
  • 4004
  • 7946354
  • GE57893
  • GO:0000122
  • GO:0003713
  • GO:0005515
  • GO:0005634
  • GO:0005654
  • GO:0006355
  • GO:0045944
  • GO:0046013
  • GO:0046872
  • GO:0140297
  • HMNXSV003047920
  • HMNXSV003056550
  • ILMN_1662917
  • M26682_at
  • PH_hs_0000150
  • TC11001385.hg
  • TC11003044.hg
  • g4505004_3p_at
physicalEntity
referenceDatabase [ReferenceDatabase:2] UniProt
referenceGene
referenceTranscript
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • RBTN1_HUMAN
  • E9PSF5
  • Q4VBC5
  • Q8IXR0
sequenceLength 156
species [Species:48887] Homo sapiens
stId uniprot:P25800
url http://purl.uniprot.org/uniprot/P25800

Referrals

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