UniProt:P23769 GATA2

chain
  • chain:1-480
checksum C879CC932C355E6A
comment
  • FUNCTION Transcriptional activator which regulates endothelin-1 gene expression in endothelial cells. Binds to the consensus sequence 5'-AGATAG-3'.SUBUNIT Interacts with BRD3 (By similarity). Interacts with AR and CCAR1. Interacts with MDFIC (By similarity).INTERACTION Endothelial cells.DISEASE The disease is caused by variants affecting the gene represented in this entry.DISEASE The disease is caused by variants affecting the gene represented in this entry.DISEASE The disease is caused by variants affecting the gene represented in this entry.SEQUENCE CAUTION Several sequencing errors.
crossReference
databaseName UniProt
dbId 55336
description
  • recommendedName: Endothelial transcription factor GATA-2 alternativeName: GATA-binding protein 2
displayName UniProt:P23769 GATA2
geneName
  • GATA2
identifier P23769
isSequenceChanged false
keyword
  • 3D-structure
  • Activator
  • Alternative splicing
  • Disease variant
  • DNA-binding
  • Isopeptide bond
  • Metal-binding
  • Methylation
  • Nucleus
  • Phagocytosis
  • Phosphoprotein
  • Proteomics identification
  • Reference proteome
  • Repeat
  • Transcription
  • Transcription regulation
  • Ubl conjugation
  • Zinc
  • Zinc-finger
modified [InstanceEdit:9926675] Weiser, Joel, 2024-11-03
moleculeType Protein
name
  • GATA2
physicalEntity
referenceDatabase [ReferenceDatabase:2] UniProt
referenceGene
referenceTranscript
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • GATA2_HUMAN
  • D3DNB3
  • Q53YE0
  • Q96BH0
  • Q96BH8
  • Q9BUJ6
sequenceLength 480
species [Species:48887] Homo sapiens
stId uniprot:P23769
url http://purl.uniprot.org/uniprot/P23769

Referrals

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