Reactome | UniProt:P20435 RPO26

Schema > ReferenceGeneProduct > Entries

UniProt:P20435 RPO26 Show undefined attributes

chain	chain:1-155
checksum	AA3DEF529F94A5E4
comment	FUNCTION DNA-dependent RNA polymerases catalyze the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. RNA polymerases are composed of mobile elements that move relative to each other. In Pol II, RPB6 is part of the clamp element and together with parts of RPB1 and RPB2 forms a pocket to which the RPB4-RPB7 subcomplex binds.SUBUNIT Component of the RNA polymerase I (Pol I), RNA polymerase II (Pol II) and RNA polymerase III (Pol III) complexes. Component of the RNA polymerase I (Pol I) complex consisting of 14 subunits: RPA135, RPA190, RPC40, RPA14, RPB5, RPO26, RPA43, RPB8, RPA12, RPB10, RPC19, RPC10, RPA49 and RPA34. The complex is composed of a horseshoe-shaped core containing ten subunits (RPA135, RPA190, RPB5, RPO26, RPB8, RPB10, RPC10, RPA12, RPC19 and RPC40) where RPA135 and RPA190 form the DNA-binding cleft. Outside of the core, RPA14 and RPA43 form the stalk that mediates interactions with transcription initiation factors and newly synthesized RNA. Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits: RPO21, RPB2, RPB3, RPB4, RPB5, RPO26, RPB7, RPB8, RPB9, RPB10 and RPC10. Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.INTERACTION Present with 6090 molecules/cell in log phase SD medium.SIMILARITY Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
crossReference	[DatabaseIdentifier:12149265] PDB:4BXX [DatabaseIdentifier:12342908] RefSeq:NP_015513.1 [DatabaseIdentifier:12254580] PRO:P20435 [DatabaseIdentifier:12163345] PDB:9G27 [DatabaseIdentifier:12163346] PDB:6RQH [DatabaseIdentifier:12163349] PDB:9G1X [DatabaseIdentifier:12149422] PDB:3GTK [DatabaseIdentifier:12145635] PDB:5SVA [DatabaseIdentifier:12149427] PDB:2E2J [DatabaseIdentifier:12149421] PDB:3GTJ [DatabaseIdentifier:12149418] PDB:3GTQ [DatabaseIdentifier:12163348] PDB:6RQL [DatabaseIdentifier:12149430] PDB:3GTG [DatabaseIdentifier:12149423] PDB:3GTL [DatabaseIdentifier:12163344] PDB:9G1V [DatabaseIdentifier:12149420] PDB:3RZD [DatabaseIdentifier:12149424] PDB:3GTM [DatabaseIdentifier:12149425] PDB:3GTO [DatabaseIdentifier:12149428] PDB:2E2I [DatabaseIdentifier:12149419] PDB:3RZO [DatabaseIdentifier:12163350] PDB:9G29 [DatabaseIdentifier:12163347] PDB:9G24 [DatabaseIdentifier:12149426] PDB:6BQF [DatabaseIdentifier:12163351] PDB:9G23 [DatabaseIdentifier:12149429] PDB:2E2H [DatabaseIdentifier:12163328] PDB:4C3H [DatabaseIdentifier:12149398] PDB:4A3C [DatabaseIdentifier:12138672] PDB:6F41 [DatabaseIdentifier:12145629] PDB:8UMH [DatabaseIdentifier:12149397] PDB:4A3B [DatabaseIdentifier:12138677] PDB:6CND [DatabaseIdentifier:12145630] PDB:8UMI [DatabaseIdentifier:12145618] PDB:7O75 [DatabaseIdentifier:12149372] PDB:8UKT [DatabaseIdentifier:12149400] PDB:4A3E [DatabaseIdentifier:12145623] PDB:7O4J [DatabaseIdentifier:12149389] PDB:5IP7 [DatabaseIdentifier:12163342] PDB:6RQT [DatabaseIdentifier:12149368] PDB:6BLP [DatabaseIdentifier:12138687] PDB:5FJ9 [DatabaseIdentifier:12149414] PDB:4A3L [DatabaseIdentifier:12163339] PDB:6HLQ [DatabaseIdentifier:12149369] PDB:6BM4 [DatabaseIdentifier:12149416] PDB:2VUM [DatabaseIdentifier:12149403] PDB:5C3E [DatabaseIdentifier:12138685] PDB:5FJA [DatabaseIdentifier:12138668] PDB:6F44 [DatabaseIdentifier:12138671] PDB:6EU3 [DatabaseIdentifier:12149391] PDB:3I4N [DatabaseIdentifier:12149407] PDB:5C4X [DatabaseIdentifier:12163335] PDB:6TPS [DatabaseIdentifier:12149367] PDB:6BM2 [DatabaseIdentifier:12149365] PDB:4BBR [DatabaseIdentifier:12149396] PDB:5C4A [DatabaseIdentifier:12149379] PDB:7RIX [DatabaseIdentifier:12149411] PDB:4A3J [DatabaseIdentifier:12149374] PDB:8UKR [DatabaseIdentifier:12145636] PDB:6GYM [DatabaseIdentifier:12149401] PDB:5C44 [DatabaseIdentifier:12149373] PDB:8UKU [DatabaseIdentifier:12149380] PDB:7RIY [DatabaseIdentifier:12149378] PDB:2R92 [DatabaseIdentifier:12138673] PDB:6EU2 [DatabaseIdentifier:12138682] PDB:6TUT [DatabaseIdentifier:12149395] PDB:3H3V [DatabaseIdentifier:12149383] PDB:2R7Z [DatabaseIdentifier:12163336] PDB:6HKO [DatabaseIdentifier:12149413] PDB:5C4J [DatabaseIdentifier:12163337] PDB:6HLS [DatabaseIdentifier:12149412] PDB:4A3K [DatabaseIdentifier:12149377] PDB:2R93 [DatabaseIdentifier:12149370] PDB:6BLO [DatabaseIdentifier:12149385] PDB:7RIP [DatabaseIdentifier:12163332] PDB:5M5W [DatabaseIdentifier:12149402] PDB:9BW0 [DatabaseIdentifier:12149408] PDB:4A3F [DatabaseIdentifier:12145624] PDB:7O4K [DatabaseIdentifier:12145631] PDB:8UOQ [DatabaseIdentifier:12138679] PDB:6CNC [DatabaseIdentifier:12149405] PDB:6GYL [DatabaseIdentifier:12149382] PDB:2B8K [DatabaseIdentifier:12149417] PDB:3GTP [DatabaseIdentifier:12149386] PDB:7RIQ [DatabaseIdentifier:12149410] PDB:4A3I [DatabaseIdentifier:12163341] PDB:9G2C [DatabaseIdentifier:12145616] PDB:7O4L [DatabaseIdentifier:12138670] PDB:6EU0 [DatabaseIdentifier:12149364] PDB:7RIM [DatabaseIdentifier:12138690] PDB:8BWS [DatabaseIdentifier:12149388] PDB:6O6C [DatabaseIdentifier:12163333] PDB:5M5Y [DatabaseIdentifier:12138681] PDB:6CNF [DatabaseIdentifier:12149393] PDB:5FYW [DatabaseIdentifier:12149375] PDB:8UKS [DatabaseIdentifier:12138676] PDB:6CNB [DatabaseIdentifier:12149399] PDB:4A3D [DatabaseIdentifier:12163340] PDB:9G2B [DatabaseIdentifier:12149371] PDB:8UKQ [DatabaseIdentifier:12163338] PDB:6HLR [DatabaseIdentifier:12138669] PDB:6EU1 [DatabaseIdentifier:12149404] PDB:6GYK [DatabaseIdentifier:12149384] PDB:1NT9 [DatabaseIdentifier:12145614] PDB:7O72 [DatabaseIdentifier:12149376] PDB:5U5Q [DatabaseIdentifier:12149387] PDB:3K7A [DatabaseIdentifier:12145619] PDB:7O73 [DatabaseIdentifier:12149366] PDB:4BBS [DatabaseIdentifier:12149415] PDB:4A3M [DatabaseIdentifier:12163334] PDB:5M64 [DatabaseIdentifier:12149406] PDB:9BVT [DatabaseIdentifier:12149363] PDB:3QT1 [DatabaseIdentifier:12145627] PDB:8UOT [DatabaseIdentifier:12138667] PDB:5FJ8 [DatabaseIdentifier:12138675] PDB:6F42 [DatabaseIdentifier:12138674] PDB:6F40 [DatabaseIdentifier:12149394] PDB:3I4M [DatabaseIdentifier:12149392] PDB:5FZ5 [DatabaseIdentifier:12163343] PDB:9G26 [DatabaseIdentifier:12149390] PDB:5IP9 [DatabaseIdentifier:12163331] PDB:5M5X [DatabaseIdentifier:12145626] PDB:7O4I [DatabaseIdentifier:12149409] PDB:4A3G [DatabaseIdentifier:12149381] PDB:7RIW [DatabaseIdentifier:12163329] PDB:4C3I [DatabaseIdentifier:12163330] PDB:4C3J [DatabaseIdentifier:12149310] PDB:3S16 [DatabaseIdentifier:12149334] PDB:8JCH [DatabaseIdentifier:12149353] PDB:1R9T [DatabaseIdentifier:12149349] PDB:9JA1 [DatabaseIdentifier:12149336] PDB:3HOU [DatabaseIdentifier:12163322] PDB:5N5Z [DatabaseIdentifier:12149330] PDB:3S1Q [DatabaseIdentifier:12145611] PDB:7ML2 [DatabaseIdentifier:12145634] PDB:8CEO [DatabaseIdentifier:12149346] PDB:3PO2 [DatabaseIdentifier:12149362] PDB:1Y77 [DatabaseIdentifier:12149326] PDB:8TVQ [DatabaseIdentifier:12149335] PDB:5W4U [DatabaseIdentifier:12163319] PDB:5W66 [DatabaseIdentifier:12149356] PDB:6UPY [DatabaseIdentifier:12149360] PDB:6UQ2 [DatabaseIdentifier:12149297] PDB:1SFO [DatabaseIdentifier:12149332] PDB:7MK9 [DatabaseIdentifier:12143834] PDB:7UIO [DatabaseIdentifier:12163327] PDB:5M3F [DatabaseIdentifier:12149342] PDB:6UQ0 [DatabaseIdentifier:12149338] PDB:3HOW [DatabaseIdentifier:12143817] PDB:8TVY [DatabaseIdentifier:12145632] PDB:8CEN [DatabaseIdentifier:12149329] PDB:7MKA [DatabaseIdentifier:12149324] PDB:3S2D [DatabaseIdentifier:12149312] PDB:3S17 [DatabaseIdentifier:12138680] PDB:7Z1O [DatabaseIdentifier:12145610] PDB:7ML4 [DatabaseIdentifier:12138688] PDB:7Z30 [DatabaseIdentifier:12149304] PDB:3K1F [DatabaseIdentifier:12149321] PDB:5W51 [DatabaseIdentifier:12149333] PDB:3J1N [DatabaseIdentifier:12149355] PDB:6UPZ [DatabaseIdentifier:12222626] PDB:8U9R [DatabaseIdentifier:12149311] PDB:9N5F [DatabaseIdentifier:12149307] PDB:3S14 [DatabaseIdentifier:12149359] PDB:6UQ3 [DatabaseIdentifier:12149320] PDB:8TVV [DatabaseIdentifier:12163321] PDB:5N5Y [DatabaseIdentifier:12149322] PDB:8TVW [DatabaseIdentifier:12149337] PDB:3HOV [DatabaseIdentifier:12149352] PDB:5VVS [DatabaseIdentifier:12149345] PDB:6I84 [DatabaseIdentifier:12149361] PDB:6UPX [DatabaseIdentifier:12149300] PDB:3S1M [DatabaseIdentifier:12149314] PDB:9N5E [DatabaseIdentifier:12149327] PDB:3S2H [DatabaseIdentifier:12163323] PDB:5N60 [DatabaseIdentifier:12149350] PDB:1I6H [DatabaseIdentifier:12149347] PDB:3PO3 [DatabaseIdentifier:12149331] PDB:3S1R [DatabaseIdentifier:12163316] PDB:6H68 [DatabaseIdentifier:12149303] PDB:8TUG [DatabaseIdentifier:12149341] PDB:3HOY [DatabaseIdentifier:12149298] PDB:1I3Q [DatabaseIdentifier:12222625] PDB:8U9X [DatabaseIdentifier:12163324] PDB:5M3M [DatabaseIdentifier:12149328] PDB:1R5U [DatabaseIdentifier:12163317] PDB:5W65 [DatabaseIdentifier:12145607] PDB:7ML1 [DatabaseIdentifier:12149309] PDB:9N5G [DatabaseIdentifier:12149318] PDB:1I50 [DatabaseIdentifier:12149351] PDB:1WCM [DatabaseIdentifier:12163314] PDB:4YM7 [DatabaseIdentifier:12138686] PDB:7Z2Z [DatabaseIdentifier:12149308] PDB:3S15 [DatabaseIdentifier:12140074] PDB:8RAP [DatabaseIdentifier:12149313] PDB:7NKX [DatabaseIdentifier:12149339] PDB:3HOX [DatabaseIdentifier:12149302] PDB:1PQV [DatabaseIdentifier:12149319] PDB:8TVX [DatabaseIdentifier:12163315] PDB:6H67 [DatabaseIdentifier:12149354] PDB:1R9S [DatabaseIdentifier:12163320] PDB:5W5Y [DatabaseIdentifier:12149316] PDB:9N5D [DatabaseIdentifier:12163312] PDB:5LMX [DatabaseIdentifier:12149358] PDB:3HOZ [DatabaseIdentifier:12163318] PDB:5W64 [DatabaseIdentifier:12163325] PDB:5N61 [DatabaseIdentifier:12149344] PDB:8K5P [DatabaseIdentifier:12149348] PDB:2B63 [DatabaseIdentifier:12149306] PDB:9N5B [DatabaseIdentifier:12163326] PDB:4C2M [DatabaseIdentifier:12149315] PDB:7NKY [DatabaseIdentifier:12140080] PDB:8RAM [DatabaseIdentifier:12149301] PDB:3S1N [DatabaseIdentifier:12143816] PDB:5VVR [DatabaseIdentifier:12145606] PDB:7ML0 [DatabaseIdentifier:12149325] PDB:8TVP [DatabaseIdentifier:12149343] PDB:3FKI [DatabaseIdentifier:12149323] PDB:3J0K [DatabaseIdentifier:12163313] PDB:5G5L [DatabaseIdentifier:12149305] PDB:9N5C [DatabaseIdentifier:12149299] PDB:1K83 [DatabaseIdentifier:12163311] PDB:6RWE [DatabaseIdentifier:12149340] PDB:6UQ1 [DatabaseIdentifier:12149357] PDB:2YU9 [DatabaseIdentifier:12149317] PDB:8TVS [DatabaseIdentifier:12138689] PDB:7Z31 [DatabaseIdentifier:12149262] PDB:2NVX [DatabaseIdentifier:12149259] PDB:1NIK [DatabaseIdentifier:12149291] PDB:7KEE [DatabaseIdentifier:12149276] PDB:1TWA [DatabaseIdentifier:12149261] PDB:4BXZ [DatabaseIdentifier:12149268] PDB:2NVZ [DatabaseIdentifier:12149292] PDB:7KEF [DatabaseIdentifier:12149284] PDB:4A93 [DatabaseIdentifier:12149278] PDB:2JA8 [DatabaseIdentifier:12149296] PDB:1Y1V [DatabaseIdentifier:12145617] PDB:7ZSA [DatabaseIdentifier:12149281] PDB:2JA6 [DatabaseIdentifier:12138683] PDB:7Z1L [DatabaseIdentifier:12145615] PDB:5OQJ [DatabaseIdentifier:12149257] PDB:2NVQ [DatabaseIdentifier:12163309] PDB:6RUI [DatabaseIdentifier:12149258] PDB:7MEI [DatabaseIdentifier:11461262] ENSEMBL:YPR187W [DatabaseIdentifier:11554458] ENSEMBL:YPR187W [DatabaseIdentifier:11677157] ENSEMBL:YPR187W_mRNA [DatabaseIdentifier:12149260] PDB:2NVY [DatabaseIdentifier:12163307] PDB:6RRD [DatabaseIdentifier:12145621] PDB:5FMF [DatabaseIdentifier:12149279] PDB:4V1O [DatabaseIdentifier:12149267] PDB:4BY1 [DatabaseIdentifier:12145620] PDB:5OQM [DatabaseIdentifier:12149277] PDB:4X6A [DatabaseIdentifier:12149285] PDB:3CQZ [DatabaseIdentifier:12149289] PDB:7KED [DatabaseIdentifier:12149275] PDB:1TWC [DatabaseIdentifier:12163310] PDB:6RUO [DatabaseIdentifier:12149269] PDB:1TWH [DatabaseIdentifier:12149287] PDB:7UIF [DatabaseIdentifier:12149282] PDB:2JA5 [DatabaseIdentifier:12149264] PDB:4BY7 [DatabaseIdentifier:12149263] PDB:2NVT [DatabaseIdentifier:12138678] PDB:7Z1N [DatabaseIdentifier:12149294] PDB:3M3Y [DatabaseIdentifier:12138684] PDB:7Z1M [DatabaseIdentifier:12149286] PDB:5OT2 [DatabaseIdentifier:12149272] PDB:1TWF [DatabaseIdentifier:12149273] PDB:4V1M [DatabaseIdentifier:12149295] PDB:1Y1W [DatabaseIdentifier:12149271] PDB:4Y7N [DatabaseIdentifier:12145622] PDB:7ZS9 [DatabaseIdentifier:12163308] PDB:5OA1 [DatabaseIdentifier:12149288] PDB:1Y1Y [DatabaseIdentifier:12149274] PDB:4V1N [DatabaseIdentifier:12145613] PDB:7ZSB [DatabaseIdentifier:12149266] PDB:4Y52 [DatabaseIdentifier:12149290] PDB:3M4O [DatabaseIdentifier:12138666] PDB:7Z0H [DatabaseIdentifier:12149270] PDB:1TWG [DatabaseIdentifier:12149280] PDB:2JA7 [DatabaseIdentifier:12149293] PDB:7UI9 [DatabaseIdentifier:12149283] PDB:4X67
databaseName	UniProt
dbId	100497
description	recommendedName: DNA-directed RNA polymerases I, II, and III subunit RPABC2 shortName: RNA polymerases I, II, and III subunit ABC2 alternativeName: ABC23 alternativeName: DNA-directed RNA polymerases I, II, and III 23 kDa polypeptide
displayName	UniProt:P20435 RPO26
geneName	RPO26 RPB6 YPR187W P9677.8
identifier	P20435
isSequenceChanged	false
keyword	3D-structure Cytoplasm DNA-directed RNA polymerase Nucleus Phosphoprotein Reference proteome Ribosome biogenesis Transcription
modified	[InstanceEdit:9926675] Weiser, Joel, 2024-11-03
moleculeType	Protein
name	RPO26
otherIdentifier	856317 GO:0000428 GO:0001054 GO:0001172 GO:0003677 GO:0003899 GO:0003968 GO:0005515 GO:0005575 GO:0005634 GO:0005654 GO:0005665 GO:0005666 GO:0005736 GO:0005737 GO:0006351 GO:0006352 GO:0006353 GO:0006354 GO:0006360 GO:0006361 GO:0006362 GO:0006363 GO:0006366 GO:0006367 GO:0006368 GO:0006383 GO:0006384 GO:0006386 GO:0016740 GO:0016779 GO:0042254 GO:0042790 GO:0042797
physicalEntity	[EntityWithAccessionedSequence:R-SCE-83714] RPO26 [nucleoplasm] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-111834] RPB6_YEAST [nucleoplasm] - Saccharomyces cerevisiae
referenceDatabase	[ReferenceDatabase:2] UniProt
referenceGene	[ReferenceDNASequence:11325725] BioGPS Gene:856317 RPO26 [ReferenceDNASequence:12731573] UCSC:P20435 RPO26 [ReferenceDNASequence:11868087] KEGG:sce:YPR187W RPO26 [ReferenceDNASequence:11955514] Monarch:856317 RPO26 [ReferenceDNASequence:12039607] NCBI Gene:856317 RPO26
referenceTranscript	[ReferenceRNASequence:12524785] RefSeq:NM_001184284.1 RPO26
schemaClass	ReferenceGeneProduct
secondaryIdentifier	RPAB2_YEAST D6W4I7
sequenceLength	155
species	[Species:68322] Saccharomyces cerevisiae
stId	uniprot:P20435
url	http://purl.uniprot.org/uniprot/P20435

Referrals

(referenceEntity)	[EntityWithAccessionedSequence:R-SCE-83714] RPO26 [nucleoplasm] [EntityWithAccessionedSequence:R-SCE-111834] RPB6_YEAST [nucleoplasm]
(interactor)	[UndirectedInteraction:11187307] UniProt:P27692 <-> UniProt:P20435 (IntAct) [UndirectedInteraction:11237961] UniProt:P32914 <-> UniProt:P20435 (IntAct)

Cite Us!