UniProt:P0C2H6 RPL27A

chain
  • initiator methionine:1
  • chain:2-136
checksum F3924B039AA2D85D
comment
  • FUNCTION Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.SUBUNIT Component of the large ribosomal subunit (LSU). Mature yeast ribosomes consist of a small (40S) and a large (60S) subunit. The 40S small subunit contains 1 molecule of ribosomal RNA (18S rRNA) and 33 different proteins (encoded by 57 genes). The large 60S subunit contains 3 rRNA molecules (25S, 5.8S and 5S rRNA) and 46 different proteins (encoded by 81 genes) (PubMed:22096102, PubMed:9559554).SUBCELLULAR LOCATION Present with 7380 molecules/cell in log phase SD medium.MISCELLANEOUS There are 2 genes for eL27 in yeast.SIMILARITY Belongs to the eukaryotic ribosomal protein eL27 family.
created [InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53
crossReference
databaseName UniProt
dbId 245837
description
  • recommendedName: fullName evidence="5"Large ribosomal subunit protein eL27A alternativeName: fullName evidence="6"60S ribosomal protein L27-A
displayName UniProt:P0C2H6 RPL27A
geneName
  • RPL27A
  • RPL27
  • YHR010W
identifier P0C2H6
isSequenceChanged false
keyword
  • 3D-structure
  • Cytoplasm
  • Reference proteome
  • Ribonucleoprotein
  • Ribosomal protein
modified [InstanceEdit:9963647] Weiser, Joel, 2025-08-15
moleculeType Protein
name
  • RPL27A
otherIdentifier
  • 856401
  • GO:0002181
  • GO:0003735
  • GO:0005198
  • GO:0005575
  • GO:0005737
  • GO:0005829
  • GO:0005840
  • GO:0006412
  • GO:0022625
  • GO:1990904
physicalEntity
referenceDatabase [ReferenceDatabase:2] UniProt
referenceGene
referenceTranscript
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • RL27A_YEAST
  • D3DKV5
  • P38706
sequenceLength 136
species [Species:68322] Saccharomyces cerevisiae
stId uniprot:P0C2H6
url http://purl.uniprot.org/uniprot/P0C2H6
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